Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Sodium/calcium exchanger membrane region
Schiff-base intermediate with dihydroxyacetone-P
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Important for guanine/8-oxoguanine distinction
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Phosphoadenosine phosphosulphate reductase
Aminoacyl-transfer RNA synthetases class-II family profile
Polymerase/histidinol phosphatase N-terminal
Glycoside hydrolase family 57 N-terminal
Hypoxanthine/guanine phosphoribosyltransferase
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Myo-inositol-1-phosphate synthase GAPDH-like
Schiff-base intermediate with D-ribose 5-phosphate
6-hydroxymethylpterin diphosphokinase MptE-like
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Abolished tRNA uridine(34) acetyltransferase activity.
Does not affect tRNA acetyl-coA hydrolase activity.
Strongly reduced tRNA acetyl-coA hydrolase activity.
Ribosomal RNA adenine methylase transferase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Small ribosomal subunit protein uS15 N-terminal
Bacterial type II secretion system protein E
Putative cytidyltransferase-related C-terminal region
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Alpha-D-phosphohexomutase alpha/beta/alpha
Polysaccharide biosynthesis protein C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Thiamine pyrophosphate enzyme TPP-binding
Pseudouridine synthase I TruA alpha/beta
Prepilin type IV endopeptidase peptidase
Calcineurin-like phosphoesterase C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Tryptophan synthase beta chain-like PALP
Thymidylate synthase/dCMP hydroxymethylase
Aspartate/homoserine dehydrogenase NAD-binding
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Interchain (with Cys-220); in linked form
Interchain (with Cys-53); in linked form
Pyruvoyl-dependent arginine decarboxylase subunit alpha
Pyruvoyl-dependent arginine decarboxylase subunit beta
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Major facilitator superfamily (MFS) profile
Anthranilate synthase component I N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
tRNA nucleotidyltransferase substrate binding
N(4)-bis(aminopropyl)spermidine synthase C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glutamate synthase alpha subunit C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Acetylserotonin O-methyltransferase dimerisation
Pyruvate/ketoisovalerate oxidoreductase catalytic
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Large ribosomal subunit protein uL15/eL18
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Methyl-coenzyme M reductase alpha subunit C-terminal
Methyl-coenzyme M reductase alpha subunit N-terminal
H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase C-terminal
Small ribosomal subunit protein uS4 N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Important for beta-aspartyl-AMP intermediate formation
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Translation elongation factor IF5A C-terminal
Transcription factor CBF/NF-Y/archaeal histone
Glycosyl transferase family 3 N-terminal
Loss of activity; when associated with A-260.
Loss of activity; when associated with A-263.
Loss of activity; when associated with A-36 and A-40.
Loss of activity; when associated with A-36 and A-43.
Loss of activity; when associated with A-40 and A-43.
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Inosine monophosphate cyclohydrolase-like
Phosphoribosylformylglycinamidine synthase linker
Small zinc finger protein HVO-2753-like zinc-binding pocket
Large ribosomal subunit protein uL6 alpha-beta
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase
Transcription factor NikR nickel binding C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glycosyltransferase subfamily 4-like N-terminal
RNA polymerase subunit H/Rpb5 C-terminal
DNA-directed RNA polymerase RBP11-like dimerisation
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Large ribosomal subunit protein uL10-like insertion
CobB/CobQ-like glutamine amidotransferase
SAM-dependent methyltransferase TRM5/TYW2-type
Alanyl-transfer RNA synthetases family profile
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Tetrahydromethanopterin S-methyltransferase F subunit
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Na+/H+ antiporter MnhB subunit-related protein
Large ribosomal subunit protein uL2 C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Glycosyl transferase family 28 C-terminal
Damage-control phosphatase ARMT1-like metal-binding
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
Non-canonical purine NTP phosphatase/PRRC1
ATPsynthase alpha/beta subunit N-terminal extension
Pyrimidine nucleoside phosphorylase C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Spo11/DNA topoisomerase VI subunit A N-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
TATA box binding protein associated factor (TAF) histone-like fold
Gamma-glutamylcyclotransferase AIG2-like
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Dihydroneopterin aldolase MtpD C-terminal
Peptidase A24A-predicted C-terminal archaea
Increases nucleophilicity of active site Cys
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Survival protein SurE-like phosphatase/nucleotidase