Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
SUF system FeS cluster assembly SufBD N-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Aminoacyl-transfer RNA synthetases class-II family profile
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Major facilitator superfamily associated
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Solute-binding protein family 3/N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Glycosyltransferase subfamily 4-like N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Cytochrome b561 bacterial/Ni-hydrogenase
O-(5'-phospho-DNA)-tyrosine intermediate
Tryptophan synthase beta chain-like PALP
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Ribose-phosphate pyrophosphokinase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Phosphoethanolamine transferase N-terminal
Major facilitator superfamily (MFS) profile
Resolvase/invertase-type recombinase catalytic
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Polypeptide-transport-associated ShlB-type
Flagellar motor switch protein FliN-like C-terminal
Membrane fusion protein biotin-lipoyl like
NIF system FeS cluster assembly NifU C-terminal
Butirosin biosynthesis protein H N-terminal
CobB/CobQ-like glutamine amidotransferase
Pyruvate/ketoisovalerate oxidoreductase catalytic
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Important for interaction with partner proteins
Urease accessory protein UreH-like transmembrane
Bacterial transcription activator effector binding
Penicillin-binding protein transpeptidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Pyridoxamine 5'-phosphate oxidase putative
NADH:ubiquinone oxidoreductase-like 20kDa subunit
TonB-dependent receptor-like beta-barrel
Damage-control phosphatase ARMT1-like metal-binding
Tellurite resistance methyltransferase TehB-like
Alpha-D-phosphohexomutase alpha/beta/alpha
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Plasminogen-binding protein PgbA N-terminal
Plasminogen-binding protein PgbA N-terminal domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Phosphoadenosine phosphosulphate reductase
Dinitrogenase iron-molybdenum cofactor biosynthesis
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
RND efflux pump membrane fusion protein barrel-sandwich
Exonuclease VII large subunit C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Survival protein SurE-like phosphatase/nucleotidase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Signal transduction histidine kinase internal region
Lysozyme inhibitor LprI N-terminal domain-containing protein
Type I restriction modification DNA specificity
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Polysaccharide biosynthesis protein CapD-like
Formylmethanofuran dehydrogenase subunit E
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
S-adenosylmethionine-dependent methyltransferase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Tripartite tricarboxylate transporter (TTT) family, substrate binding protein
Acyl-CoA dehydrogenase C-terminal bacterial-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Bacterial type II secretion system protein E
NADH:ubiquinone oxidoreductase 30kDa subunit
O-(3'-phospho-DNA)-tyrosine intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Organic solvent tolerance-like N-terminal
Prokaryotic-type class I peptide chain release factors
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Polysaccharide chain length determinant N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Nucleophile; cysteine thiosulfonate intermediate
Small ribosomal subunit protein uS4 N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Large ribosomal subunit protein uL15/eL18
ATP-grasp fold succinyl-CoA synthetase-type
DNA mismatch repair proteins mutS family
UDP-N-acetylenolpyruvoylglucosamine reductase C-terminal
DNA replication/recombination mediator RecO N-terminal
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Pseudouridine synthase I TruA alpha/beta
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
6-hydroxymethylpterin diphosphokinase MptE-like
DNA-directed DNA polymerase family A palm
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Thymidylate synthase/dCMP hydroxymethylase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Restriction endonuclease type II DpnII-like
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Moybdenum cofactor oxidoreductase dimerisation
Helix-hairpin-helix DNA-binding motif class 1
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Carbamoyl-phosphate synthase small subunit N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Sodium symporter small subunit predicted
Electron transfer via tryptophanyl radical
Large ribosomal subunit protein uL2 C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Ribosomal RNA adenine methylase transferase N-terminal
Plays an important role in substrate specificity
NIF system FeS cluster assembly NifU N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Pyruvate dehydrogenase E1 component middle
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein uL6 alpha-beta
Mandelate racemase/muconate lactonizing enzyme C-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
ATP synthase F1 complex delta/epsilon subunit N-terminal
Alginate lyase 2 domain-containing protein
Shikimate dehydrogenase substrate binding N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
RNA binding; important for wobble base 34 recognition
Ionotropic glutamate receptor C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Translation elongation factor P/YeiP central
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Sugar fermentation stimulation protein C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Type VI secretion system IcmF C-terminal
Inner membrane protein YgaP-like transmembrane
Important for beta-aspartyl-AMP intermediate formation
Sodium/calcium exchanger membrane region
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
RNA 2-O ribose methyltransferase substrate binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Periplasmic nitrate reductase, electron transfer subunit
Outer membrane protein beta-barrel domain-containing protein
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Anthranilate synthase component I N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Fibrobacter succinogenes major paralogous
Polymerase/histidinol phosphatase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Flagellar hook-length control protein-like C-terminal
Alanyl-transfer RNA synthetases family profile
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
CD-NTase-associated protein 12/Pycsar effector protein TIR
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Reversibly protonated during proton transport
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Probable glycerophosphodiester phosphodiesterase GpdQ
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
L-cysteine S-thiosulfotransferase subunit SoxA
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Nitrogenase molybdenum-iron protein beta chain N-terminal
Quinoprotein dehydrogenase-associated SoxYZ-like carrier
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Alpha-glycerophosphate oxidase C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
N-end rule aminoacyl transferase C-terminal
Threonine/serine exporter-like N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Saccharopine dehydrogenase-like C-terminal
Involved in allosteric activation by GTP
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Chromosomal replication initiator DnaA C-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
Molybdopterin cofactor biosynthesis C (MoaC)
Essential for prephenate dehydratase activity
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
UDP N-acetylglucosamine O-acyltransferase C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
ABC-type glycine betaine transport system substrate-binding
Membrane insertase YidC/Oxa/ALB C-terminal