Aminoacyl-transfer RNA synthetases class-II family profile
Peptidase M1 membrane alanine aminopeptidase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
CobB/CobQ-like glutamine amidotransferase
Alanyl-transfer RNA synthetases family profile
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Schiff-base intermediate with D-ribose 5-phosphate
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Thiamine pyrophosphate enzyme TPP-binding
Glycosyltransferase subfamily 4-like N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Major facilitator superfamily (MFS) profile
Prepilin type IV endopeptidase peptidase
Aldehyde ferredoxin oxidoreductase N-terminal
RNA 3'-terminal phosphate cyclase insert
Large ribosomal subunit protein uL15/eL18
CRISPR system ring nuclease SSO1393-like
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Pyruvate/ketoisovalerate oxidoreductase catalytic
Removed in mature form; by autocatalysis
SAM-dependent methyltransferase TRM5/TYW2-type
Tryptophan synthase beta chain-like PALP
Ribosomal RNA adenine methylase transferase N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
RNA polymerase subunit H/Rpb5 C-terminal
Glycoside hydrolase family 57 N-terminal
Cytochrome c-552/DMSO reductase-like haem-binding
Transcription factor NikR nickel binding C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Alpha-D-phosphohexomutase alpha/beta/alpha
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
tRNA nucleotidyltransferase substrate binding
Methionyl-tRNA synthetase anticodon-binding
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Iron dependent repressor metal binding and dimerisation
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Damage-control phosphatase ARMT1-like metal-binding
Myo-inositol-1-phosphate synthase GAPDH-like
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Peptidase S9 prolyl oligopeptidase catalytic
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Bacterial type II secretion system protein E
S-adenosyl-L-homocysteine hydrolase NAD binding
Schiff-base intermediate with acetaldehyde
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Translation elongation factor IF5A C-terminal
Thiosulphate:quinone oxidoreductase small subunit DoxA
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Large ribosomal subunit protein uL10-like insertion
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Small ribosomal subunit protein uS15 N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Spo11/DNA topoisomerase VI subunit A N-terminal
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
Cytochrome b/b6 N-terminal region profile
2,4-diaminopentanoate dehydrogenase C-terminal
Dihydrodipicolinate reductase N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Plays an important role in substrate specificity
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
CRISPR-associated protein Cmr2 N-terminal
Nitrite/Sulfite reductase ferredoxin-like
YbaK/aminoacyl-tRNA synthetase-associated
Gfo/Idh/MocA-like oxidoreductase N-terminal
Non-canonical purine NTP phosphatase/PRRC1
Large ribosomal subunit protein uL6 alpha-beta
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
SUF system FeS cluster assembly SufBD N-terminal
Schiff-base intermediate with dihydroxyacetone-P
Phosphoribosylformylglycinamidine synthase linker
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Type IV secretion system coupling protein TraD DNA-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Pseudouridine synthase I TruA alpha/beta
Serine/threonine specific protein phosphatases
NADH:ubiquinone oxidoreductase 30kDa subunit
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Helix-hairpin-helix DNA-binding motif class 1
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Aminoacyl-tRNA synthetase class I anticodon-binding
D-galactarate/Altronate dehydratase C-terminal
Large ribosomal subunit protein uL2 C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Transcription factor CBF/NF-Y/archaeal histone
Siroheme decarboxylase AsnC-like ligand binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Aspartate/homoserine dehydrogenase NAD-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Sugar fermentation stimulation protein C-terminal
Small zinc finger protein HVO-2753-like zinc-binding pocket
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Bacterial bifunctional deaminase-reductase C-terminal
Small ribosomal subunit protein uS4 N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Signal recognition particle SRP54 helical bundle
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
DNA-directed RNA polymerase RBP11-like dimerisation
TRASH transcription regulator C-terminal archaeal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Pyruvate phosphate dikinase AMP/ATP-binding
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Sodium/calcium exchanger membrane region