DNA-directed RNA polymerase RpoA/D/Rpb3-type
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cell envelope-related transcriptional attenuator
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
RNA polymerase sigma factor 70 region 4 type 2
Endoribonuclease L-PSP/chorismate mutase-like
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Alpha-glycerophosphate oxidase C-terminal
Major facilitator superfamily (MFS) profile
Gram-positive pilin subunit D1 N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Prokaryotic-type class I peptide chain release factors
Tryptophan synthase beta chain-like PALP
Membrane insertase YidC/Oxa/ALB C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Large ribosomal subunit protein uL6 alpha-beta
Gly-cisPro motif, important for rejection of L-amino acids
Phosphotransferase system enzyme I N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Phosphomannose isomerase type I catalytic
Type III restriction enzyme C-terminal endonuclease
Plays an important role in substrate specificity
Cysteine sulfenic acid (-SOH) intermediate
Positions MEP for the nucleophilic attack
4'-phosphopantetheinyl transferase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Prealbumin-like fold domain-containing protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Ribose-phosphate pyrophosphokinase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Interaction with polymerase core subunit RpoC
RNA 2-O ribose methyltransferase substrate binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
6-phosphogluconate dehydrogenase C-terminal
Penicillin-binding protein transpeptidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Large ribosomal subunit protein uL15/eL18
Alpha-D-phosphohexomutase alpha/beta/alpha
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Cytochrome C biogenesis protein transmembrane
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Peptidase M1 membrane alanine aminopeptidase
Ribosomal RNA adenine methylase transferase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Cytochrome oxidase subunit II copper A binding
Ribosome maturation factor RimP N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Translation elongation factor P/YeiP central
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Aminoacyl-transfer RNA synthetases class-II family profile
Glucosamine/galactosamine-6-phosphate isomerase
Phosphocysteine intermediate; for EIIB activity
Thiostrepton-resistance methylase N-terminal
DNA-directed DNA polymerase family A palm
Putative Flp pilus-assembly TadG-like N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
CobB/CobQ-like glutamine amidotransferase
ATP-dependent DNA helicase RecG C-terminal
NIF system FeS cluster assembly NifU N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Peptide methionine sulphoxide reductase MsrA
Inosine/uridine-preferring nucleoside hydrolase
Thymidylate synthase/dCMP hydroxymethylase
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Cytochrome b/b6 N-terminal region profile
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Pyruvate phosphate dikinase AMP/ATP-binding
Could be important to modulate the pK values of the two catalytic cysteine residues
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Release factor glutamine methyltransferase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Polysaccharide biosynthesis protein C-terminal
Gram-positive cocci surface proteins LPxTG domain-containing protein
Alanyl-transfer RNA synthetases family profile
SUF system FeS cluster assembly SufBD N-terminal
PhoD-like phosphatase metallophosphatase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Phosphatidic acid phosphatase type 2/haloperoxidase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Peptidase propeptide domain-containing protein
Threonine/serine exporter-like N-terminal
Actinobacterial surface-anchored protein domain
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Anthranilate synthase component I N-terminal
Trigger factor ribosome-binding bacterial
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Pseudouridine synthase I TruA alpha/beta
Bacterial type II secretion system protein E
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Cell wall-binding repeat 2 family protein
Increases nucleophilicity of active site Cys
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Reversibly protonated during proton transport
S-adenosyl-L-homocysteine hydrolase NAD binding
DNA replication/recombination mediator RecO N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
ABC-type glycine betaine transport system substrate-binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Pyrimidine nucleoside phosphorylase C-terminal
Schiff-base intermediate with acetaldehyde
Phosphoribosylformylglycinamidine synthase linker
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Polymerase/histidinol phosphatase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
TrbL/VirB6 plasmid conjugal transfer protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Large ribosomal subunit protein uL2 C-terminal
Important for beta-aspartyl-AMP intermediate formation
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cell wall-active antibiotics response LiaF-like C-terminal
Arabinofuranosyltransferase AftA C-terminal
Arabinofuranosyltransferase AftA N-terminal
Glycine cleavage T-protein C-terminal barrel
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Involved in ionization of N3 of dUMP, leading to its activation
Important for substrate specificity; cannot use PPi as phosphoryl donor
Peptidase S9 prolyl oligopeptidase catalytic
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Fibrinogen C-terminal domain-containing protein
Carboxypeptidase regulatory-like domain-containing protein
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Exonuclease VII large subunit C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
YbaK/aminoacyl-tRNA synthetase-associated
Essential for prephenate dehydratase activity
Pyruvate dehydrogenase E1 component middle
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Glycosyl transferase family 3 N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Solute-binding protein family 3/N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Bacterial Ig-like domain-containing protein
Sporulation transcription regulator WhiA N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Small ribosomal subunit protein uS4 N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Peptidoglycan recognition protein family
Inner membrane protein YgaP-like transmembrane