FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Flagellar hook-length control protein-like C-terminal
Major facilitator superfamily (MFS) profile
Flagellar basal body rod protein N-terminal
Positions MEP for the nucleophilic attack
Ribosomal RNA small subunit methyltransferase E methyltransferase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Mannose-6-phosphate isomerase type II C-terminal
Pyridoxamine 5'-phosphate oxidase putative
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Transposase IS116/IS110/IS902 C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Urease accessory protein UreH-like transmembrane
RND efflux pump membrane fusion protein barrel-sandwich
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Flagella basal body P-ring formation protein FlgA
Glycosyltransferase subfamily 4-like N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Thymidylate synthase/dCMP hydroxymethylase
Phosphatidic acid phosphatase type 2/haloperoxidase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Phosphotransferase system enzyme I N-terminal
Tryptophan synthase beta chain-like PALP
Probable transposase IS891/IS1136/IS1341
Putative ATP-dependent zinc protease domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Translation elongation factor P/YeiP central
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Ysc84 actin-binding domain-containing protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Type II secretion system protein GspG C-terminal
Outer-membrane lipoprotein carrier protein
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Could play a key role in the communication between the regulatory and the substrate sites
Alpha-D-phosphohexomutase alpha/beta/alpha
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Putative exodeoxyribonuclease 8 PDDEXK-like
Large ribosomal subunit protein uL6 alpha-beta
YbaK/aminoacyl-tRNA synthetase-associated
Zinc-regulated TonB-dependent outer membrane receptor
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Flagellar basal-body/hook protein C-terminal
Interaction with polymerase core subunit RpoC
Aminoacyl-transfer RNA synthetases class-II family profile
N6 adenine-specific DNA methyltransferase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Cytochrome c-type biogenesis protein CcmF C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Chromosomal replication initiator DnaA C-terminal
Release factor glutamine methyltransferase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Cytochrome b561 bacterial/Ni-hydrogenase
Reversibly protonated during proton transport
N-end rule aminoacyl transferase C-terminal
Flagellar motor switch protein FliN-like C-terminal
Proton acceptor; for glutaminase activity
Could be important to modulate the pK values of the two catalytic cysteine residues
Electron transfer via tryptophanyl radical
NIF system FeS cluster assembly NifU C-terminal
Phosphoadenosine phosphosulphate reductase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
DNA polymerase III delta subunit C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Flagellar assembly protein FliH/Type III secretion system HrpE
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Bacterial type II secretion system protein E
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Important for interaction with partner proteins
Polysaccharide biosynthesis protein C-terminal
Heme-copper oxidase subunit III family profile
High potential iron-sulfur proteins family profile
Biopterin-dependent aromatic amino acid hydroxylase family profile
Prokaryotic-type class I peptide chain release factors
NIF system FeS cluster assembly NifU N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Type I restriction modification DNA specificity
3-beta hydroxysteroid dehydrogenase/isomerase
Terminase large subunit-like endonuclease
Pyruvate/ketoisovalerate oxidoreductase catalytic
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Putative regulatory protein FmdB Zinc ribbon
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Large ribosomal subunit protein uL15/eL18
Glycine cleavage T-protein C-terminal barrel
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Endolytic peptidoglycan transglycosylase RlpA
Transcriptional regulator SgrR N-terminal HTH
TonB-dependent receptor-like beta-barrel
Resolvase/invertase-type recombinase catalytic
Spore coat protein U domain-containing protein
Inosine/uridine-preferring nucleoside hydrolase
Translocation and assembly module subunit TamA
Glucosamine/galactosamine-6-phosphate isomerase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Type II secretion system protein GspC N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Phosphocysteine intermediate; for EIIB activity
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Photosynthesis system II assembly factor Ycf48/Hcf136-like
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Outer membrane lipoprotein-sorting protein
Small ribosomal subunit protein uS4 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Terminase large subunit gp17-like C-terminal
DNA mismatch repair proteins mutS family
Outer membrane protein assembly factor BamE
Molybdopterin cofactor biosynthesis C (MoaC)
Chalcone isomerase domain-containing protein
Anthranilate synthase component I N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
ABC-type uncharacterised transport system
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Thiol:disulfide interchange protein DsbA
Mandelate racemase/muconate lactonizing enzyme C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
Type IV secretion system coupling protein TraD DNA-binding
O-(3'-phospho-DNA)-tyrosine intermediate
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Transposase IS204/IS1001/IS1096/IS1165 DDE
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Transition state stabilizer; via amide nitrogen
ABC-type transport auxiliary lipoprotein component
Gfo/Idh/MocA-like oxidoreductase N-terminal
Polysaccharide chain length determinant N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
Polysaccharide biosynthesis protein CapD-like
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Gly-cisPro motif, important for rejection of L-amino acids
Polymerase/histidinol phosphatase N-terminal
Organic solvent tolerance-like N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Pyruvate dehydrogenase E1 component middle
Hypersensitivity response secretion-like HrpJ
Type III secretion system effector delivery regulator TyeA
O-(5'-phospho-DNA)-tyrosine intermediate
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Superoxide dismutase copper/zinc binding
RNA polymerase sigma factor 70 region 4 type 2
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Sodium symporter small subunit predicted
Disulphide bond isomerase DsbC/G N-terminal
Membrane fusion protein biotin-lipoyl like
CRISPR-associated protein Cas6 C-terminal
Type II secretion system protein GspI C-terminal
AMP-activated protein kinase glycogen-binding
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Helix-hairpin-helix DNA-binding motif class 1
Aconitase A/isopropylmalate dehydratase small subunit swivel
Large ribosomal subunit protein uL2 C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Shikimate dehydrogenase substrate binding N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Pyrimidine nucleoside phosphorylase C-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
Outer membrane protein beta-barrel domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
Solute-binding protein family 3/N-terminal
High-affinity zinc uptake system protein ZnuA
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Bacterial bifunctional deaminase-reductase C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
ATPsynthase alpha/beta subunit N-terminal extension
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Signal transduction histidine kinase internal region
Pseudouridine synthase I TruA alpha/beta
Sugar fermentation stimulation protein C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Alanyl-transfer RNA synthetases family profile
Plays an important role in discriminating NADH against NADPH
Plays an important role in substrate specificity
Type 4 fimbrial biogenesis protein PilX N-terminal
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Glycosyl transferase family 3 N-terminal
RNA 2-O ribose methyltransferase substrate binding
ExoP galactose-binding-like domain-containing protein
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Cysteine sulfenic acid (-SOH) intermediate
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Lipoprotein SmpA/OmlA domain-containing protein
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Threonine/serine exporter-like N-terminal
Conserved virulence factor B-like winged helix
Outer membrane protein assembly factor BamA
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Interacts with tRNA; defines subfamily-specific binding signature
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
6-hydroxymethylpterin diphosphokinase MptE-like
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Lantibiotic biosynthesis protein dehydration
MalT-like TPR region domain-containing protein
Prepilin type IV endopeptidase peptidase
Haem-binding uptake Tiki superfamily ChaN
Chromosome partition protein MukF C-terminal
Chromosome partition protein MukF middle
Chromosome partition protein MukF winged-helix
DNA polymerase III subunit delta C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Peptide methionine sulphoxide reductase MsrA
Peptidase S9 prolyl oligopeptidase catalytic
DNA replication/recombination mediator RecO N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Important for autoinhibition of adenylyltransferase activity