Tryptophan synthase beta chain-like PALP
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Cation-transporting P-type ATPase N-terminal
Major facilitator superfamily (MFS) profile
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
CagE TrbE VirB component of type IV transporter system central
Plasmid replication protein C C-terminal
Plasmid replication protein C N-terminal
Important for interaction with partner proteins
Heme-copper oxidase subunit III family profile
RND efflux pump membrane fusion protein barrel-sandwich
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Chromosomal replication initiator DnaA C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Signal recognition particle SRP54 helical bundle
Interaction with polymerase core subunit RpoC
FAD-dependent oxidoreductase 2 FAD binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Anthranilate synthase component I N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Reversibly protonated during proton transport
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Glucose-methanol-choline oxidoreductase N-terminal
D-lactate dehydrogenase membrane binding C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Phosphoribosylformylglycinamidine synthase linker
Prokaryotic-type class I peptide chain release factors
Alpha-D-phosphohexomutase alpha/beta/alpha
Amidohydrolase 3 domain-containing protein
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Membrane fusion protein biotin-lipoyl like
RNA 2-O ribose methyltransferase substrate binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Proline utilization A proline dehydrogenase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Helix-hairpin-helix DNA-binding motif class 1
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
DNA replication/recombination mediator RecO N-terminal
Probable periplasmic serine endoprotease DegP-like
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Type I restriction modification DNA specificity
Calcium/calmodulin-dependent protein kinase II association-domain
Calcium/calmodulin-dependent protein kinase II association-domain domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Guanylate kinase/L-type calcium channel beta subunit
CDP-alcohol phosphatidyltransferase C-terminal
Transcription elongation factor GreA/GreB C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Sugar fermentation stimulation protein C-terminal
Apiosidase-like catalytic domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
S-adenosylmethionine-dependent methyltransferase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
O-(3'-phospho-DNA)-tyrosine intermediate
C-type lysozyme inhibitor domain-containing protein
Translation elongation factor P/YeiP central
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
ATP synthase F1 complex delta/epsilon subunit N-terminal
Large ribosomal subunit protein uL2 C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Nitrite/Sulfite reductase ferredoxin-like
Outer membrane protein assembly factor BamA
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19
N,N-dimethylformamidase beta subunit-like C-terminal
Cytochrome c oxidase subunit IV bacterial aa3 type
Survival protein SurE-like phosphatase/nucleotidase
Cobaltochelatase subunit CobS N-terminal
cyclic-guanylate-specific phosphodiesterase
Required for zinc-mediated homotetramerization and catalytic activity
Cytochrome b561 bacterial/Ni-hydrogenase
ABC transporter substrate-binding protein PnrA-like
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Thymidylate synthase/dCMP hydroxymethylase
Penicillin-binding protein transpeptidase
SGNH hydrolase-type esterase domain-containing protein
Thiamin pyrophosphokinase thiamin-binding
Superoxide dismutase copper/zinc binding
N-end rule aminoacyl transferase C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Tetrahydrodipicolinate-N-succinyltransferase chain A
Cysteine sulfenic acid (-SOH) intermediate
SUF system FeS cluster assembly SufBD N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Polymerase/histidinol phosphatase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
UDP N-acetylglucosamine O-acyltransferase C-terminal
Phosphoethanolamine transferase N-terminal
Glycine cleavage T-protein C-terminal barrel
Transcription factor NikR nickel binding C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Alanyl-transfer RNA synthetases family profile
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Acyl-CoA dehydrogenase N-terminal bacteria
Pseudouridine synthase I TruA alpha/beta
Flagellar motor switch protein FliN-like C-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Transcription elongation factor GreA/GreB N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Beta-lactamase hydrolase-like protein phosphatase-like
Endoribonuclease L-PSP/chorismate mutase-like
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Methionyl-tRNA synthetase anticodon-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Molybdopterin cofactor biosynthesis C (MoaC)
Transglycosylase SLT domain-containing protein
NADH:ubiquinone oxidoreductase chain 4 N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
6-phosphogluconate dehydrogenase C-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Involved in tetramerization or stability of the tetramer
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Cytochrome c-type biogenesis protein CcmF C-terminal
Alpha-glycerophosphate oxidase C-terminal
Regulator of nucleoside diphosphate kinase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
RNA binding; important for wobble base 34 recognition
Peptide methionine sulphoxide reductase MsrA
Polysaccharide biosynthesis protein CapD-like
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
TonB-dependent receptor-like beta-barrel
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Tat (Twin-arginine translocation) pathway signal sequence domain protein
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Saccharopine dehydrogenase-like C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Small ribosomal subunit protein uS4 N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
DNA-directed RNA polymerase RpoA/D/Rpb3-type
ABC-type glycine betaine transport system substrate-binding
Cytochrome oxidase subunit II copper A binding
N6 adenine-specific DNA methyltransferase N-terminal
Exonuclease VII large subunit C-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Could be important to modulate the pK values of the two catalytic cysteine residues
Membrane insertase YidC/Oxa/ALB C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
RNA polymerase sigma factor 70 region 4 type 2
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Ribose-phosphate pyrophosphokinase N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Histidine phosphotransferase ChpT C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Outer membrane protein beta-barrel domain-containing protein
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Transcription regulator AsnC/Lrp ligand binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Plays an important role in substrate specificity
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Interacts with tRNA; defines subfamily-specific binding signature
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
NADH:ubiquinone oxidoreductase 30kDa subunit
DNA-directed DNA polymerase family A palm
Na+/H+ antiporter MnhB subunit-related protein
High-affinity zinc uptake system protein ZnuA
Phosphatidic acid phosphatase type 2/haloperoxidase
Large ribosomal subunit protein uL15/eL18
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
3-beta hydroxysteroid dehydrogenase/isomerase
Mannose-6-phosphate isomerase type II C-terminal
Phosphodiester glycosidase domain-containing protein
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
NIF system FeS cluster assembly NifU N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Resolvase/invertase-type recombinase catalytic
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
DNA mismatch repair proteins mutS family
Glycosyl transferase family 3 N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Type IV secretion system putative lipoprotein virB7
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
TtsA-like Glycoside hydrolase family 108
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Polysaccharide chain length determinant N-terminal
Flagella basal body P-ring formation protein FlgA
Flagella basal body P-ring formation protein FlgA C-terminal
Essential for prephenate dehydratase activity
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
S-adenosyl-L-homocysteine hydrolase NAD binding
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal