Aminoacyl-transfer RNA synthetases class-II family profile
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Phosphotransferase system enzyme I N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Penicillin-binding protein transpeptidase
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
O-(5'-phospho-DNA)-tyrosine intermediate
Major facilitator superfamily (MFS) profile
Large ribosomal subunit protein uL2 C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Transcriptional regulator LacI/GalR-like sensor
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Sporulation transcription regulator WhiA N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Alpha-D-phosphohexomutase alpha/beta/alpha
RNA 2-O ribose methyltransferase substrate binding
Glycosyltransferase subfamily 4-like N-terminal
Exonuclease VII large subunit C-terminal
Cation-transporting P-type ATPase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
DNA replication/recombination mediator RecO N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Tryptophan synthase beta chain-like PALP
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Inosine/uridine-preferring nucleoside hydrolase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Translation elongation factor P/YeiP central
YbaK/aminoacyl-tRNA synthetase-associated
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Periplasmic binding protein domain-containing protein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Prepilin type IV endopeptidase peptidase
Bacterial type II secretion system protein E
Large ribosomal subunit protein uL6 alpha-beta
Peptidase M1 membrane alanine aminopeptidase
Glycoside hydrolase family 42 N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Gram-positive cocci surface proteins LPxTG
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
O-(3'-phospho-DNA)-tyrosine intermediate
Phosphatidylglycerol lysyltransferase C-terminal
Type I restriction enzyme R protein N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Membrane iron-sulfur containing protein FtrD-like
N6 adenine-specific DNA methyltransferase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Chromosomal replication initiator DnaA C-terminal
Large ribosomal subunit protein uL15/eL18
Ribose-phosphate pyrophosphokinase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
NAD(P) transhydrogenase alpha subunit C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Could be important to modulate the pK values of the two catalytic cysteine residues
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Ribosomal RNA small subunit methyltransferase E methyltransferase
Positions MEP for the nucleophilic attack
NIF system FeS cluster assembly NifU N-terminal
Solute-binding protein family 3/N-terminal
Small ribosomal subunit protein uS4 N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Ribosomal RNA adenine methylase transferase N-terminal
Phosphatidate phosphatase APP1 catalytic
Proton acceptor; for glutaminase activity
DNA-directed DNA polymerase family A palm
Thiamin pyrophosphokinase thiamin-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Essential for prephenate dehydratase activity
Polymerase/histidinol phosphatase N-terminal
Anthranilate synthase component I N-terminal
Amino acid ABC transporter substrate-binding protein
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Putative regulatory protein FmdB Zinc ribbon
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Gram-positive pilin backbone subunit 2 Cna-B-like
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Glycosyl transferase family 3 N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Alanyl-transfer RNA synthetases family profile
Probable transposase IS891/IS1136/IS1341
Glucosamine/galactosamine-6-phosphate isomerase
Pyridoxamine 5'-phosphate oxidase putative
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Glycosyl hydrolase family 30 beta sandwich
Could play a key role in the communication between the regulatory and the substrate sites
Myo-inositol-1-phosphate synthase GAPDH-like
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Reversibly protonated during proton transport
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Pseudouridine synthase I TruA alpha/beta
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Choloylglycine hydrolase/NAAA C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cobalamin-independent methionine synthase MetE N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Resolvase/invertase-type recombinase catalytic
CobB/CobQ-like glutamine amidotransferase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
tRNA pseudouridylate synthase B C-terminal
Phosphoribosylformylglycinamidine synthase linker