Prokaryotic-type class I peptide chain release factors
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
O-(3'-phospho-DNA)-tyrosine intermediate
Prepilin type IV endopeptidase peptidase
Penicillin-binding protein transpeptidase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Tryptophan synthase beta chain-like PALP
Flagellar motor switch protein FliN N-terminal
Flagellar motor switch protein FliN-like C-terminal
Major facilitator superfamily (MFS) profile
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Transcriptional regulator SgrR N-terminal HTH
Interaction with polymerase core subunit RpoC
Solute-binding protein family 3/N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Important for substrate binding and specificity
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Schiff-base intermediate with acetaldehyde
Polysaccharide chain length determinant N-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Flagella basal body P-ring formation protein FlgA
Flagellar assembly protein FliH/Type III secretion system HrpE
Sodium/calcium exchanger membrane region
Tetrahydrodipicolinate-N-succinyltransferase chain A
YbaK/aminoacyl-tRNA synthetase-associated
RND efflux pump membrane fusion protein barrel-sandwich
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Outer membrane protein assembly factor BamD
Thiol:disulfide interchange protein DsbD
Involved in proton transfer during cleavage
TRAP C4-dicarboxylate transport system permease DctM subunit
Phosphoethanolamine transferase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Gly-cisPro motif, important for rejection of L-amino acids
Interaction with tRNA; Important for base-flipping
Pseudouridine synthase I TruA alpha/beta
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Survival protein SurE-like phosphatase/nucleotidase
TonB-dependent receptor-like beta-barrel
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Superoxide dismutase copper/zinc binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Phosphocysteine intermediate; for EIIB activity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Type III secretion system flagellar brake protein YcgR PilZN
Outer membrane protein assembly factor BamB
Outer-membrane lipoprotein carrier protein
Small ribosomal subunit protein uS4 N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Involved in allosteric activation by GTP
Mandelate racemase/muconate lactonizing enzyme C-terminal
Ionotropic glutamate receptor C-terminal
DnaJ homologue subfamily C member 28 conserved
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Threonine/serine exporter-like N-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Integral membrane protein YccS N-terminal
RNA 2-O ribose methyltransferase substrate binding
Regulator of nucleoside diphosphate kinase N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Ribose-phosphate pyrophosphokinase N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Phosphotransferase system enzyme I N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Plays an important role in substrate specificity
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Important for interaction with partner proteins
Glucan biosynthesis periplasmic MdoG C-terminal
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Reversibly protonated during proton transport
DNA replication/recombination mediator RecO N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Required for dimer formation and molybdate binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Transglycosylase PBP1b N-terminal transmembrane
Large ribosomal subunit protein bL25 L25
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Resolvase/invertase-type recombinase catalytic
Large ribosomal subunit protein uL15/eL18
Peptide methionine sulphoxide reductase MsrA
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Nucleoside-specific channel-forming protein Tsx
Organic solvent tolerance-like N-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Chromosome partition protein MukF C-terminal
Chromosome partition protein MukF middle
Chromosome partition protein MukF winged-helix
Pyruvate phosphate dikinase AMP/ATP-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Malonate/sodium symporter MadM subunit N-terminal
Alanyl-transfer RNA synthetases family profile
Chromosomal replication initiator DnaA C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Mediates proton transfer from the outer aqueous phase to the interior of the protein; involved in linking H(+) and Cl(-) transport
Mediates proton transfer from the protein to the inner aqueous phase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Heme-copper oxidase subunit III family profile
Major facilitator superfamily associated
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Lipopolysaccharide export system protein LptA
Membrane fusion protein biotin-lipoyl like
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Pyruvate dehydrogenase E1 component middle
RNA binding; important for wobble base 34 recognition
Pyrimidine nucleoside phosphorylase C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Thiol:disulfide interchange protein DsbL
Large ribosomal subunit protein uL2 C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
ABC-type transport auxiliary lipoprotein component
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Translation elongation factor P/YeiP central
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Mechanosensitive ion channel inner membrane
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Transcription factor NikR nickel binding C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Prepilin peptidase dependent protein C-like C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Phosphatidic acid phosphatase type 2/haloperoxidase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle