Gly-cisPro motif, important for rejection of L-amino acids
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Threonine/serine exporter-like N-terminal
Flagellar Assembly Protein A N-terminal region
RNA binding; important for wobble base 34 recognition
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Cytochrome b561 bacterial/Ni-hydrogenase
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Sporulation transcription regulator WhiA N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Could be important to modulate the pK values of the two catalytic cysteine residues
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Organic solvent tolerance-like N-terminal
Polymerase/histidinol phosphatase N-terminal
Mannose-6-phosphate isomerase type II C-terminal
LPS export ABC transporter periplasmic protein LptC
HicB-like antitoxin of toxin-antitoxin system
Aminoacyl-transfer RNA synthetases class-II family profile
Dihydrodipicolinate reductase N-terminal
Meso-diaminopimelate D-dehydrogenase C-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Glycosyltransferase family 28 N-terminal
Solute-binding protein family 3/N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Transcription regulator AsnC/Lrp ligand binding
Glycoside-hydrolase family GH114 TIM-barrel
Glycosyl transferase family 3 N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Tryptophan synthase beta chain-like PALP
P-type conjugative transfer protein TrbJ
Chromosomal replication initiator DnaA C-terminal
Helix-hairpin-helix DNA-binding motif class 1
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Important for autoinhibition of adenylyltransferase activity
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
TonB-dependent receptor-like beta-barrel
Phosphotransferase system enzyme I N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Major facilitator superfamily (MFS) profile
Dinitrogenase iron-molybdenum cofactor biosynthesis
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Phosphatidic acid phosphatase type 2/haloperoxidase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Siroheme decarboxylase AsnC-like ligand binding
Bacterial type II secretion system protein E
Phosphocysteine intermediate; for EIIB activity
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Cell envelope-related transcriptional attenuator
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Type I restriction modification DNA specificity
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Proton acceptor; for glutaminase activity
Large ribosomal subunit protein uL6 alpha-beta
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
ATP-dependent DNA helicase RecG C-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Dihydrodipicolinate reductase C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Exonuclease VII large subunit C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Polysaccharide biosynthesis protein CapD-like
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
RNA 2-O ribose methyltransferase substrate binding
Pyrimidine nucleoside phosphorylase C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Large ribosomal subunit protein uL15/eL18
Involved in allosteric activation by GTP
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Polypeptide-transport-associated ShlB-type
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Penicillin-binding protein transpeptidase
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
UDP-glucose/GDP-mannose dehydrogenase C-terminal
tRNA pseudouridylate synthase B C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Cytochrome C biogenesis protein transmembrane
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
DNA replication/recombination mediator RecO N-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Translation elongation factor P/YeiP central
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Resolvase/invertase-type recombinase catalytic
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Small ribosomal subunit protein uS4 N-terminal
Phosphodiester glycosidase domain-containing protein
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Prepilin type IV endopeptidase peptidase
Ionotropic glutamate receptor C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Iron hydrogenase large subunit C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
UDP N-acetylglucosamine O-acyltransferase C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain-containing protein
Flagellar motor switch protein FliN-like C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
YbaK/aminoacyl-tRNA synthetase-associated
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Survival protein SurE-like phosphatase/nucleotidase
DNA mismatch repair proteins mutS family
FAD-dependent oxidoreductase 2 FAD binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Flagellar assembly protein FliH/Type III secretion system HrpE
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Septum formation inhibitor MinC C-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Polysaccharide chain length determinant N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
NIF system FeS cluster assembly NifU N-terminal
Terminase large subunit gp17-like C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Interaction with polymerase core subunit RpoC
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Thiamin pyrophosphokinase thiamin-binding
Flagella basal body P-ring formation protein FlgA
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Ribonucleotide reductase large subunit C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Carbamoyl-phosphate synthetase large subunit-like ATP-binding
Magnesium transporter MgtE intracellular
Polysaccharide biosynthesis protein C-terminal
Flagellar hook-length control protein-like C-terminal
DNA-directed DNA polymerase family A palm
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Cytochrome c-type biogenesis protein CcmF C-terminal
Signal recognition particle SRP54 helical bundle
Phosphatidylglycerol lysyltransferase C-terminal
Membrane iron-sulfur containing protein FtrD-like
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Schiff-base intermediate with acetaldehyde
Positions MEP for the nucleophilic attack
Aconitase A/isopropylmalate dehydratase small subunit swivel
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Release factor glutamine methyltransferase N-terminal
Phosphoribosylformylglycinamidine synthase linker
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Ribose-phosphate pyrophosphokinase N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Important for interaction with partner proteins
Alanyl-transfer RNA synthetases family profile
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Peptide methionine sulphoxide reductase MsrA
Saccharopine dehydrogenase-like C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Ribosomal RNA adenine methylase transferase N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Essential for prephenate dehydratase activity
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Reversibly protonated during proton transport
Pseudouridine synthase I TruA alpha/beta
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
NADH:ubiquinone oxidoreductase 30kDa subunit
SUF system FeS cluster assembly SufBD N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Carbamoyl-phosphate synthase small subunit N-terminal