Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Tryptophan synthase beta chain-like PALP
Glycine cleavage T-protein C-terminal barrel
FAD-dependent oxidoreductase 2 FAD binding
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Bacterial type II secretion system protein E
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glutamate synthase alpha subunit C-terminal
Group 4 capsule polysaccharide lipoprotein gfcB, YjbF
DNA replication/recombination mediator RecO N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Transcriptional regulator AbiEi antitoxin N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
PhoD-like phosphatase metallophosphatase
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Aminoacyl-transfer RNA synthetases class-II family profile
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
RND efflux pump membrane fusion protein barrel-sandwich
NIF system FeS cluster assembly NifU N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Plays an important role in substrate specificity
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Transcription regulator AsnC/Lrp ligand binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Probable periplasmic serine endoprotease DegP-like
Nuclear transport factor 2 family protein
Saccharopine dehydrogenase-like C-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
tRNA pseudouridylate synthase B C-terminal
Outer membrane protein beta-barrel domain-containing protein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Glucose-methanol-choline oxidoreductase N-terminal
ABC-type glycine betaine transport system substrate-binding
Major facilitator superfamily (MFS) profile
Alanyl-transfer RNA synthetases family profile
RNA polymerase sigma factor 70 region 4 type 2
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
TtsA-like Glycoside hydrolase family 108
Cytochrome c oxidase subunit IV bacterial aa3 type
Phenol hydroxylase C-terminal dimerisation
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Proton acceptor; for glutaminase activity
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glucose-methanol-choline oxidoreductase C-terminal
Peptide methionine sulphoxide reductase MsrA
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Release factor glutamine methyltransferase N-terminal
Transposase IS116/IS110/IS902 C-terminal
Membrane fusion protein biotin-lipoyl like
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
TonB-dependent receptor-like beta-barrel
Cysteine sulfenic acid (-SOH) intermediate
DNA mismatch repair proteins mutS family
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Transcription elongation factor GreA/GreB C-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
ABC transporter substrate-binding protein PnrA-like
Aconitase A/isopropylmalate dehydratase small subunit swivel
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Sodium/calcium exchanger membrane region
DnaJ homologue subfamily C member 28 conserved
Cytochrome oxidase subunit II copper A binding
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Alpha-D-phosphohexomutase alpha/beta/alpha
Flagellar basal-body/hook protein C-terminal
Methionyl-tRNA synthetase anticodon-binding
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
6-phosphogluconate dehydrogenase C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Photosynthetic reaction centre H subunit N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
SUF system FeS cluster assembly SufBD N-terminal
Interaction with polymerase core subunit RpoC
Heat-inducible transcription repressor HrcA C-terminal
Translation elongation factor P/YeiP central
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Transcription elongation factor GreA/GreB N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Polysaccharide chain length determinant N-terminal
Penicillin-binding protein transpeptidase
Large ribosomal subunit protein uL15/eL18
Resolvase/invertase-type recombinase catalytic
Sugar fermentation stimulation protein C-terminal
Cation-transporting P-type ATPase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Polymerase/histidinol phosphatase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Pyridoxamine 5'-phosphate oxidase putative
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Carbamoyl-phosphate synthase small subunit N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Small ribosomal subunit protein uS4 N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Caspase family p20 domain-containing protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Flagellar motor switch protein FliN-like C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Alpha-glycerophosphate oxidase C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Pseudouridine synthase I TruA alpha/beta
Anthranilate synthase component I N-terminal
Large ribosomal subunit protein uL2 C-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Magnesium chelatase subunit H N-terminal
Curli production assembly/transport component CsgF
ABC-type transport auxiliary lipoprotein component
Reversibly protonated during proton transport
S-adenosylmethionine-dependent methyltransferase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Endoribonuclease L-PSP/chorismate mutase-like
Nitrite/Sulfite reductase ferredoxin-like
Survival protein SurE-like phosphatase/nucleotidase
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Acyl-CoA dehydrogenase C-terminal bacterial-type
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Ribose-phosphate pyrophosphokinase N-terminal
Inner membrane protein YgaP-like transmembrane
Cytochrome C biogenesis protein transmembrane
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Interacts with tRNA; defines subfamily-specific binding signature
Solute-binding protein family 3/N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Helix-hairpin-helix DNA-binding motif class 1
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
peptide-methionine (R)-S-oxide reductase
Lysozyme inhibitor LprI N-terminal domain-containing protein
Acetyl-CoA dehydrogenase-like C-terminal
Prokaryotic-type class I peptide chain release factors
Membrane insertase YidC/Oxa/ALB C-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Excalibur calcium-binding domain-containing protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Proline utilization A proline dehydrogenase N-terminal
Chromosomal replication initiator DnaA C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Periplasmic nitrate reductase, electron transfer subunit
Putative Flp pilus-assembly TadG-like N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Protocatechuate 3,4-dioxygenase beta subunit N-terminal
Electron transfer via tryptophanyl radical
Important for interaction with partner proteins
Antitoxin Xre/MbcA/ParS-like toxin-binding
PHA accumulation regulator DNA-binding N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Involved in ionization of N3 of dUMP, leading to its activation
Mannose-6-phosphate isomerase type II C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Signal recognition particle SRP54 helical bundle
Bacterial transcription activator effector binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Plasmid replication protein C C-terminal
Plasmid replication protein C N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Glycosyl transferase family 3 N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Terminase large subunit-like endonuclease
UDP N-acetylglucosamine O-acyltransferase C-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Sigma 54 modulation/S30EA ribosomal protein C-terminal
General stress protein FMN-binding split barrel
Flagellar basal body rod protein N-terminal
Magnesium-protoporphyrin IX methyltransferase C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
S-adenosyl-L-homocysteine hydrolase NAD binding
Polysaccharide biosynthesis protein CapD-like
4'-phosphopantetheinyl transferase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Leucine-binding protein domain-containing protein
Cobaltochelatase subunit CobS N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Moybdenum cofactor oxidoreductase dimerisation
Required for zinc-mediated homotetramerization and catalytic activity
Acyl-CoA dehydrogenase N-terminal bacteria
Chromosomal replication initiator protein DnaA
Pyrimidine nucleoside phosphorylase C-terminal
Adaptive response protein AidB N-terminal
Sulfatase-modifying factor enzyme domain-containing protein
Terminase large subunit gp17-like C-terminal
Cytochrome oxidase subunit II transmembrane region profile
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
N-end rule aminoacyl transferase C-terminal
RNA 2-O ribose methyltransferase substrate binding
Flavocytochrome c sulphide dehydrogenase flavin-binding
Prepilin type IV endopeptidase peptidase
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Outer membrane lipoprotein-sorting protein
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Inosine/uridine-preferring nucleoside hydrolase
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Heme-copper oxidase subunit III family profile
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Exonuclease VII large subunit C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
ATP-grasp fold succinyl-CoA synthetase-type
Biopterin-dependent aromatic amino acid hydroxylase family profile
Acetylserotonin O-methyltransferase dimerisation
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Histidine phosphotransferase ChpT C-terminal
Haem-binding uptake Tiki superfamily ChaN
ATP synthase F1 complex delta/epsilon subunit N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Tat pathway signal sequence domain protein
Arginine decarboxylase C-terminal helical
Beta-lactamase hydrolase-like protein phosphatase-like
Glycosyltransferase subfamily 4-like N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Type II secretion system protein TadB-like N-terminal
Cyclophilin-like domain-containing protein
Gly-cisPro motif, important for rejection of L-amino acids
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Thiopeptide-type bacteriocin biosynthesis
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Type I restriction modification DNA specificity
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Gamma-glutamylcyclotransferase AIG2-like
DNA primase/polymerase bifunctional N-terminal
Lantibiotic biosynthesis protein dehydration
Phosphodiester glycosidase domain-containing protein
DNA-directed DNA polymerase family A palm