Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Aminoacyl-transfer RNA synthetases class-II family profile
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
RNA 2-O ribose methyltransferase substrate binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Tryptophan synthase beta chain-like PALP
DNA mismatch repair proteins mutS family
DNA replication/recombination mediator RecO N-terminal
Solute-binding protein family 3/N-terminal
Lytic transglycosylase superhelical linker
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Chromosomal replication initiator DnaA C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Penicillin-binding protein transpeptidase
Type I restriction modification DNA specificity
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor
Trimeric autotransporter adhesin YadA-like head
Trimeric autotransporter adhesin YadA-like stalk
TonB-dependent receptor-like beta-barrel
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Essential for prephenate dehydratase activity
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
RNA binding; important for wobble base 34 recognition
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Thiol:disulfide interchange protein DsbD
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Small ribosomal subunit protein uS4 N-terminal
S-adenosylmethionine-dependent methyltransferase
O-(5'-phospho-DNA)-tyrosine intermediate
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Prokaryotic-type class I peptide chain release factors
O-(3'-phospho-DNA)-tyrosine intermediate
Helix-hairpin-helix DNA-binding motif class 1
Glycosyl transferase family 3 N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Membrane insertase YidC/Oxa/ALB C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Large ribosomal subunit protein uL2 C-terminal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
ATP synthase F1 complex delta/epsilon subunit N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Could be important to modulate the pK values of the two catalytic cysteine residues
Phosphotransferase system enzyme I N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Anti-bacteriophage protein A/HamA C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
DNA polymerase III delta subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
ABC-type transport auxiliary lipoprotein component
DNA-directed DNA polymerase family A palm
Polysaccharide biosynthesis protein CapD-like
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Survival protein SurE-like phosphatase/nucleotidase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Major facilitator superfamily (MFS) profile
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Positions MEP for the nucleophilic attack
Type ISP restriction-modification enzyme LLaBIII C-terminal specificity
Transferrin-binding protein B C-lobe/N-lobe beta barrel
Interacts with tRNA; defines subfamily-specific binding signature
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Interaction with polymerase core subunit RpoC
Required for zinc-mediated homotetramerization and catalytic activity
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Gly-cisPro motif, important for rejection of L-amino acids
6-phosphogluconate dehydrogenase C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Bacterial type II secretion system protein E
Translation elongation factor P/YeiP central
Aminoacyl-tRNA synthetase class I anticodon-binding
Transposase IS116/IS110/IS902 C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Outer membrane protein assembly factor BamC
Tetrahydrodipicolinate-N-succinyltransferase chain A
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Alanyl-transfer RNA synthetases family profile
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Phosphoethanolamine transferase N-terminal
Prepilin type IV endopeptidase peptidase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
YbaK/aminoacyl-tRNA synthetase-associated
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Release factor glutamine methyltransferase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Plays an important role in substrate specificity
Anthranilate synthase component I N-terminal
Large ribosomal subunit protein uL15/eL18
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Outer membrane protein assembly factor BamA
Outer-membrane lipoprotein carrier protein
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
NIF system FeS cluster assembly NifU N-terminal
Exonuclease VII large subunit C-terminal
Glycine cleavage T-protein C-terminal barrel
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Tellurite resistance methyltransferase TehB-like
SGNH hydrolase-type esterase domain-containing protein
RND efflux pump membrane fusion protein barrel-sandwich
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Butirosin biosynthesis protein H N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Ionotropic glutamate receptor C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Integral membrane protein YccS N-terminal
Pyruvate dehydrogenase E1 component middle
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
BAAT/Acyl-CoA thioester hydrolase C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Polymerase/histidinol phosphatase N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Pseudouridine synthase I TruA alpha/beta
Carbamoyl-phosphate synthase small subunit N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Proline utilization A proline dehydrogenase N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Urease accessory protein UreH-like transmembrane
Peptidase C-terminal archaeal/bacterial domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Type 4 fimbrial biogenesis protein PilX N-terminal
Shikimate dehydrogenase substrate binding N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Threonine/serine exporter-like N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Tle cognate immunity protein 4 C-terminal
Tle cognate immunity protein 4 C-terminal domain-containing protein
Gamma-butyrobetaine hydroxylase-like N-terminal