tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Sodium/calcium exchanger membrane region
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Phosphogluconate dehydrogenase (decarboxylating) C-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
Survival protein SurE-like phosphatase/nucleotidase
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Tryptophan synthase beta chain-like PALP
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor
Trimeric autotransporter adhesin YadA-like head
Trimeric autotransporter adhesin YadA-like stalk
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Flagellar basal body rod protein N-terminal
Sel1 domain protein repeat-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
ABC-type glycine betaine transport system substrate-binding
Glutamate synthase alpha subunit C-terminal
RNA 2-O ribose methyltransferase substrate binding
Solute-binding protein family 3/N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Methylaspartate ammonia-lyase C-terminal
Methylaspartate ammonia-lyase N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Glycine cleavage T-protein C-terminal barrel
RND efflux pump membrane fusion protein barrel-sandwich
NIF system FeS cluster assembly NifU N-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Organic solvent tolerance-like N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Lysozyme inhibitor LprI N-terminal domain-containing protein
Transposase IS116/IS110/IS902 C-terminal
Major facilitator superfamily (MFS) profile
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Bacterial bifunctional deaminase-reductase C-terminal
Penicillin-binding protein transpeptidase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Flagellar basal-body/hook protein C-terminal
6-phosphogluconate dehydrogenase C-terminal
Interaction with polymerase core subunit RpoC
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Ionotropic glutamate receptor C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Flagellar motor switch protein FliN-like C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Methionyl-tRNA synthetase anticodon-binding
RNA polymerase sigma factor 70 region 4 type 2
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Periplasmic binding protein domain-containing protein
Bacterial type II secretion system protein E
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
TRAP C4-dicarboxylate transport system permease DctM subunit
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19
Peptide methionine sulphoxide reductase MsrA
NADH:ubiquinone oxidoreductase-like 20kDa subunit
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Transcription regulator AsnC/Lrp ligand binding
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
DNA polymerase III beta sliding clamp central
Polysaccharide chain length determinant N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Saccharopine dehydrogenase-like C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Putative Flp pilus-assembly TadG-like N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Mandelate racemase/muconate lactonizing enzyme C-terminal
FAD-dependent oxidoreductase 2 FAD binding
DNA primase/polymerase bifunctional N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Tat pathway signal sequence domain protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Peptidase S9 prolyl oligopeptidase catalytic
Schiff-base intermediate with acetoacetate
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Essential for prephenate dehydratase activity
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Inosine/uridine-preferring nucleoside hydrolase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Cytochrome C biogenesis protein transmembrane
ATP-grasp fold succinyl-CoA synthetase-type
Glucose-methanol-choline oxidoreductase N-terminal
Peptidase M17 leucyl aminopeptidase N-terminal
Pseudouridine synthase I TruA alpha/beta
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Protein-L-isoaspartate O-methyltransferase
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
YbaK/aminoacyl-tRNA synthetase-associated
ABC transporter substrate-binding protein PnrA-like
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Activator of Hsp90 ATPase homologue 1-like C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
O-(5'-phospho-DNA)-tyrosine intermediate
AB hydrolase-1 domain-containing protein
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Exonuclease VII large subunit C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Tetrahydrodipicolinate-N-succinyltransferase chain A
Putative glycogen debranching enzyme N-terminal
ABC-type transport auxiliary lipoprotein component
Ribosomal RNA adenine methylase transferase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Aconitase A/isopropylmalate dehydratase small subunit swivel
Ribulose bisphosphate carboxylase small subunit
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Endoribonuclease L-PSP/chorismate mutase-like
Molybdopterin cofactor biosynthesis C (MoaC)
Guanylate kinase/L-type calcium channel beta subunit
PHA accumulation regulator DNA-binding N-terminal
Release factor glutamine methyltransferase N-terminal
Alanyl-transfer RNA synthetases family profile
O-(3'-phospho-DNA)-tyrosine intermediate
NADH:ubiquinone oxidoreductase 30kDa subunit
DNA-directed RNA polymerase RpoA/D/Rpb3-type
DNA mismatch repair proteins mutS family
Chromosomal replication initiator DnaA C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Reversibly protonated during proton transport
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
N,N-dimethylformamidase beta subunit-like C-terminal
Alpha-glycerophosphate oxidase C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Large ribosomal subunit protein uL2 C-terminal
Flagella basal body P-ring formation protein FlgA
Flagella basal body P-ring formation protein FlgA C-terminal
Important for interaction with partner proteins
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Glucosamine/galactosamine-6-phosphate isomerase
Pyruvate phosphate dikinase AMP/ATP-binding
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
RNA binding; important for wobble base 34 recognition
Transcription elongation factor GreA/GreB C-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Outer membrane protein assembly factor BamD
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
DNA topoisomerase I catalytic core eukaryotic-type
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Outer membrane protein assembly factor BamA
Plays an important role in substrate specificity
Membrane fusion protein biotin-lipoyl like
Probable periplasmic serine endoprotease DegP-like
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
TtsA-like Glycoside hydrolase family 108
Ribose-phosphate pyrophosphokinase N-terminal
S-adenosylmethionine-dependent methyltransferase
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
4'-phosphopantetheinyl transferase N-terminal
Microcin J25-processing protein McjB C-terminal
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
Pili assembly chaperone N-terminal domain-containing protein
Prepilin type IV endopeptidase peptidase
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Septum formation inhibitor MinC C-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Signal transduction histidine kinase HWE region
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Polysaccharide biosynthesis protein C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Prokaryotic-type class I peptide chain release factors
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
Gamma-butyrobetaine hydroxylase-like N-terminal
Translation elongation factor P/YeiP central
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Nitrogenase molybdenum-iron protein beta chain N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Myo-inositol-1-phosphate synthase GAPDH-like
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
Polymerase/histidinol phosphatase N-terminal
Cytochrome c oxidase subunit IV bacterial aa3 type
Pyruvate/ketoisovalerate oxidoreductase catalytic
Heme-copper oxidase subunit III family profile
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Flagellar hook-length control protein-like C-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Biopterin-dependent aromatic amino acid hydroxylase family profile
Lipocalin-like domain-containing protein
Pyrimidine nucleoside phosphorylase C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Anthranilate synthase component I N-terminal
Methylene-tetrahydrofolate reductase C-terminal
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Phosphatidylglycerol lysyltransferase C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Adaptive response protein AidB N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Large ribosomal subunit protein uL15/eL18
C-type lysozyme inhibitor domain-containing protein
CagE TrbE VirB component of type IV transporter system central
BAAT/Acyl-CoA thioester hydrolase C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Thiamin pyrophosphokinase thiamin-binding
Resolvase/invertase-type recombinase catalytic
SUF system FeS cluster assembly SufBD N-terminal
Interacts with tRNA; defines subfamily-specific binding signature
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Large ribosomal subunit protein uL6 alpha-beta
5-glutamyl coenzyme A thioester intermediate
Could play a key role in the communication between the regulatory and the substrate sites
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Peptide methionine sulfoxide reductase MsrA
Cytochrome c-type biogenesis protein CcmF C-terminal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
DNA replication/recombination mediator RecO N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Poly-beta-hydroxybutyrate polymerase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Proline utilization A proline dehydrogenase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Regulator of nucleoside diphosphate kinase N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Proton acceptor; for glutaminase activity
Histidine phosphotransferase ChpT C-terminal
N-end rule aminoacyl transferase C-terminal
Leucine-binding protein domain-containing protein
Abortive infection protein-like C-terminal
Glycosyl transferase family 3 N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Sulfatase-modifying factor enzyme domain-containing protein
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Cob(I)alamin adenosyltransferase N-terminal
Schiff-base intermediate with dihydroxyacetone-P
Major facilitator superfamily associated
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Small ribosomal subunit protein uS4 N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
UDP N-acetylglucosamine O-acyltransferase C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Molybdenum cofactor biosynthesis protein F N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Pilus formation protein N-terminal domain-containing protein
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Spore coat protein U domain-containing protein