FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Major facilitator superfamily (MFS) profile
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Cytochrome b/b6 N-terminal region profile
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
RNA polymerase sigma factor 70 region 4 type 2
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glycosyltransferase family 28 N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Ribosomal RNA adenine methylase transferase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
2,4-diaminopentanoate dehydrogenase C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Sodium/calcium exchanger membrane region
Protein O-mannosyl-transferase C-terminal four TM
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Tryptophan synthase beta chain-like PALP
Thymidylate synthase/dCMP hydroxymethylase
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Peptide methionine sulphoxide reductase MsrA
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycosyl transferase family 28 C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Polymerase/histidinol phosphatase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Acetylserotonin O-methyltransferase dimerisation
Saccharopine dehydrogenase-like C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Putative regulatory protein FmdB Zinc ribbon
TRAP C4-dicarboxylate transport system permease DctM subunit
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
NIF system FeS cluster assembly NifU N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Alpha-D-phosphohexomutase alpha/beta/alpha
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Bacterial bifunctional deaminase-reductase C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-102)
Ribulose bisphosphate carboxylase small subunit
Heme-copper oxidase subunit III family profile
Reversibly protonated during proton transport
5-glutamyl coenzyme A thioester intermediate
Penicillin-binding protein transpeptidase
Thiamine pyrophosphate enzyme TPP-binding
Schiff-base intermediate with dihydroxyacetone-P
Cytochrome bc1 complex cytochrome c subunit
Glycine cleavage T-protein C-terminal barrel
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Putative glycogen debranching enzyme N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Translation elongation factor P/YeiP central
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Lactate utilization protein B C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
MmyB-like transcription regulator ligand binding
Dihydrodipicolinate reductase N-terminal
Small ribosomal subunit protein uS4 N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Important for substrate specificity; cannot use PPi as phosphoryl donor
Chromosomal replication initiator DnaA C-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Aconitase A/isopropylmalate dehydratase small subunit swivel
Prokaryotic-type class I peptide chain release factors
Glycosyltransferase subfamily 4-like N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Superoxide dismutase copper/zinc binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
ABC-type glycine betaine transport system substrate-binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
CobB/CobQ-like glutamine amidotransferase
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Carbamoyl-phosphate synthase small subunit N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Glutamate synthase alpha subunit C-terminal
Schiff-base intermediate with substrate; via topaquinone
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
DNA topoisomerase I catalytic core eukaryotic-type
NADH:ubiquinone oxidoreductase 30kDa subunit
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glutathionylspermidine synthase pre-ATP-grasp-like
Alpha-glycerophosphate oxidase C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Cytochrome bc1 complex Rieske iron-sulfur subunit
Large ribosomal subunit protein uL15/eL18
Gly-cisPro motif, important for rejection of L-amino acids
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Homogentisate 1,2-dioxygenase N-terminal
Anthranilate synthase component I N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic