Helix-hairpin-helix DNA-binding motif class 1
Phage conserved hypothetical protein C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
M protein trans-acting positive regulator (MGA) HTH
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Cell wall-active antibiotics response LiaF-like C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Major facilitator superfamily (MFS) profile
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
DNA-directed DNA polymerase family A palm
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
DNA mismatch repair proteins mutS family
Type VII secretion system protein EssD-like
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
S-adenosylmethionine-dependent methyltransferase
Aminoacyl-transfer RNA synthetases class-II family profile
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Peptide methionine sulphoxide reductase MsrA
Peptidase S9 prolyl oligopeptidase catalytic
Membrane protein 6-pyruvoyl-tetrahydropterin synthase-related
Phosphocysteine intermediate; for EIIB activity
Polysaccharide biosynthesis protein CapD-like
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glycosyltransferase 2-like prokaryotic type
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Penicillin-binding protein transpeptidase
O-(3'-phospho-DNA)-tyrosine intermediate
Phosphomannose isomerase type I catalytic
Membrane insertase YidC/Oxa/ALB C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Release factor glutamine methyltransferase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Thiamin pyrophosphokinase thiamin-binding
Transcriptional coactivator p15 (PC4) C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Probable transposase IS891/IS1136/IS1341
Ricin B lectin domain-containing protein
Bacterial bifunctional deaminase-reductase C-terminal
tRNA pseudouridylate synthase B C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
TRAP C4-dicarboxylate transport system permease DctM subunit
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
2,4-diaminopentanoate dehydrogenase C-terminal
Dihydrodipicolinate reductase N-terminal
Phosphatidylglycerol lysyltransferase C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Cation-transporting P-type ATPase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Signal transduction histidine kinase internal region
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Glycosyltransferase subfamily 4-like N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Polysaccharide biosynthesis protein C-terminal
Sporulation transcription regulator WhiA N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Tryptophan synthase beta chain-like PALP
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Choloylglycine hydrolase/NAAA C-terminal
Gram-positive pilin subunit D1 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Pseudouridine synthase I TruA alpha/beta
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Cell envelope-related transcriptional attenuator
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
O-(5'-phospho-DNA)-tyrosine intermediate
RNA polymerase sigma factor 70 region 4 type 2
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Terminase large subunit-like endonuclease
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
ABC transporter substrate-binding protein PnrA-like
SUF system FeS cluster assembly SufBD N-terminal
Bacterial type II secretion system protein E
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Zn-dependent metallo-hydrolase RNA specificity
Shikimate dehydrogenase substrate binding N-terminal
LPXTG cell wall anchor domain-containing protein
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Reversibly protonated during proton transport
TRAP dicarboxylate transporter subunit DctP
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Important for interaction with partner proteins
Prokaryotic-type class I peptide chain release factors
Pectate lyase superfamily protein domain-containing protein
DNA replication/recombination mediator RecO N-terminal
Sugar fermentation stimulation protein C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Threonine/serine exporter-like N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Dihydrodipicolinate reductase C-terminal
HicB-like antitoxin of toxin-antitoxin system
Ankyrin repeat domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Putative aromatic acid exporter C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glucosamine/galactosamine-6-phosphate isomerase
BspA family leucine-rich repeat surface protein
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Schiff-base intermediate with acetaldehyde
Translation elongation factor P/YeiP central
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
DNA/pantothenate metabolism flavoprotein C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Interaction with polymerase core subunit RpoC
Gram-positive cocci surface proteins LPxTG domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Alpha-glycerophosphate oxidase C-terminal
RNA 2-O ribose methyltransferase substrate binding
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein uL2 C-terminal
Small ribosomal subunit protein uS4 N-terminal
6-phosphogluconate dehydrogenase C-terminal
Chromosomal replication initiator DnaA C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
CobB/CobQ-like glutamine amidotransferase
Resolvase/invertase-type recombinase catalytic
Polysaccharide lyase 8 N-terminal alpha-helical
Polysaccharide lyase family 8 C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Plays an important role in substrate specificity
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Important for beta-aspartyl-AMP intermediate formation
Menaquinone biosynthesis protein MenD middle
Major facilitator superfamily associated
Glycoside hydrolase family 42 N-terminal
Carbohydrate-binding domain-containing protein
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Important for autoinhibition of adenylyltransferase activity
Glycoside hydrolase family 31 N-terminal
Large ribosomal subunit protein uL15/eL18
Phosphatidic acid phosphatase type 2/haloperoxidase
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Gram-positive cocci surface proteins LPxTG
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Type I restriction modification DNA specificity
Phosphotransferase system enzyme I N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Essential for prephenate dehydratase activity
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Exonuclease VII large subunit C-terminal
Polysaccharide chain length determinant N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Lysidine-tRNA(Ile) synthetase C-terminal
Conserved hypothetical protein CHP02679 N terminus
Bacterial EndoU nuclease domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Elongation factor G-binding protein N-terminal
Involved in allosteric activation by GTP
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
YbaK/aminoacyl-tRNA synthetase-associated
Thymidylate synthase/dCMP hydroxymethylase
NIF system FeS cluster assembly NifU N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
FAD-dependent oxidoreductase 2 FAD binding
Pesticidal crystal protein Cry22Aa Ig-like domain-containing protein
ABC-type glycine betaine transport system substrate-binding
Alanyl-transfer RNA synthetases family profile
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Conserved virulence factor B-like winged helix
RND efflux pump membrane fusion protein barrel-sandwich
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Inosine/uridine-preferring nucleoside hydrolase
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Pesticidal crystal protein Cry22Aa Ig-like
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
O-(phosphoribosyl dephospho-coenzyme A)serine
Phosphoribosylformylglycinamidine synthase linker
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor