3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
C-type lysozyme inhibitor domain-containing protein
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Glucose/Sorbosone dehydrogenase domain-containing protein
Organic solvent tolerance-like N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Lysozyme inhibitor LprI N-terminal domain-containing protein
PHA accumulation regulator DNA-binding N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Solute-binding protein family 3/N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glycine cleavage T-protein C-terminal barrel
Pyrimidine nucleoside phosphorylase C-terminal
Essential for prephenate dehydratase activity
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
N6 adenine-specific DNA methyltransferase N-terminal
N-end rule aminoacyl transferase C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Restriction system protein Mrr-like N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Involved in ionization of N3 of dUMP, leading to its activation
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Transcription factor NikR nickel binding C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Tryptophan synthase beta chain-like PALP
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Probable transposase IS891/IS1136/IS1341
Sugar fermentation stimulation protein C-terminal
Major facilitator superfamily (MFS) profile
Cysteine sulfenic acid (-SOH) intermediate
Aminoacyl-transfer RNA synthetases class-II family profile
Activator of Hsp90 ATPase homologue 1-like C-terminal
RNA 2-O ribose methyltransferase substrate binding
O-(phosphoribosyl dephospho-coenzyme A)serine
RND efflux pump membrane fusion protein barrel-sandwich
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
TonB-dependent receptor-like beta-barrel
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Methylene-tetrahydromethanopterin dehydrogenase N-terminal
Bacterial toxin 46 domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
ATP synthase F1 complex delta/epsilon subunit N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Magnesium transporter MgtE intracellular
DNA replication/recombination mediator RecO N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
FAD-dependent oxidoreductase 2 FAD binding
Mannose-6-phosphate isomerase type II C-terminal
Carbohydrate binding module xylan-binding
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Beta-lactamase-related domain-containing protein
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Periplasmic nitrate reductase, electron transfer subunit
Transcription regulator AsnC/Lrp ligand binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Nitrite/Sulfite reductase ferredoxin-like
Molybdopterin cofactor biosynthesis C (MoaC)
Glycine zipper 2TM domain-containing protein
Pyridoxamine 5'-phosphate oxidase putative
Polymerase/histidinol phosphatase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Phosphoribosylformylglycinamidine synthase linker
NIF system FeS cluster assembly NifU C-terminal
NIF system FeS cluster assembly NifU N-terminal
Probable periplasmic serine endoprotease DegP-like
Outer membrane protein assembly factor BamA
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
RNA polymerase sigma factor 70 region 4 type 2
Leucine-binding protein domain-containing protein
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Anthranilate synthase component I N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Right handed beta helix domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Putative regulatory protein FmdB Zinc ribbon
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Polysaccharide biosynthesis protein C-terminal
Small-conductance mechanosensitive channel
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Proton acceptor; for glutaminase activity
Interacts with tRNA; defines subfamily-specific binding signature
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Membrane fusion protein biotin-lipoyl like
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Penicillin-binding protein transpeptidase
Guanylate cyclase domain-containing protein
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Phosphatidic acid phosphatase type 2/haloperoxidase
Terminase large subunit-like endonuclease
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
AB hydrolase-1 domain-containing protein
Flagellar motor switch protein FliN-like C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Chromosomal replication initiator protein DnaA
Ribose-phosphate pyrophosphokinase N-terminal
Release factor glutamine methyltransferase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Heme-copper oxidase subunit III family profile
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Histidine phosphotransferase ChpT C-terminal
Cytochrome P460 domain-containing protein
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Reversibly protonated during proton transport
Malonate/sodium symporter MadM subunit N-terminal
Electron transfer via tryptophanyl radical
Small ribosomal subunit protein uS4 N-terminal
PrcB C-terminal domain-containing protein
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Shikimate dehydrogenase substrate binding N-terminal
RNA binding; important for wobble base 34 recognition
Outer membrane lipoprotein carrier protein LolA
Membrane insertase YidC/Oxa/ALB C-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Cyclophilin-like domain-containing protein
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Translation elongation factor P/YeiP central
Quinoprotein dehydrogenase-associated SoxYZ-like carrier
Peptide methionine sulphoxide reductase MsrA
Glycosyltransferase subfamily 4-like N-terminal
Signal transduction histidine kinase HWE region
Required for zinc-mediated homotetramerization and catalytic activity
Endolytic peptidoglycan transglycosylase RlpA
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
ABC-type glycine betaine transport system substrate-binding
Important for beta-aspartyl-AMP intermediate formation
Bacterial bifunctional deaminase-reductase C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Cytochrome b561 bacterial/Ni-hydrogenase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
DNA-directed DNA polymerase family A palm
Carbamoyl-phosphate synthase small subunit N-terminal
EfeO-type cupredoxin-like domain-containing protein
Alanyl-transfer RNA synthetases family profile
Resolvase/invertase-type recombinase catalytic
Heat-inducible transcription repressor HrcA C-terminal
Aromatic-ring-hydroxylating dioxygenase alpha subunit C-terminal
Glycosyl transferase family 3 N-terminal
Inner membrane protein YgaP-like transmembrane
tRNA pseudouridylate synthase B C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Endoribonuclease L-PSP/chorismate mutase-like
Pectate lyase superfamily protein domain-containing protein
Pseudouridine synthase I TruA alpha/beta
Urease accessory protein UreH-like transmembrane
Chromosomal replication initiator DnaA C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Phosphotransferase system enzyme I N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Ribosomal RNA adenine methylase transferase N-terminal
Regulator of nucleoside diphosphate kinase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Survival protein SurE-like phosphatase/nucleotidase
Gamma-butyrobetaine hydroxylase-like N-terminal
BioF2-like acetyltransferase domain-containing protein
Outer membrane protein assembly factor BamD
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Polysaccharide biosynthesis protein CapD-like
Citrate transporter-like domain-containing protein
Cobaltochelatase subunit CobS N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Flagellar basal body-associated protein FliL
Surface antigen domain-containing protein
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
C4-dicarboxylate ABC transporter substrate-binding protein
HupH hydrogenase expression protein C-terminal
Large ribosomal subunit protein uL15/eL18
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Large ribosomal subunit protein uL2 C-terminal
Solute-binding protein family 5 domain-containing protein
Glutathionylspermidine synthase pre-ATP-grasp-like
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
DNA mismatch repair proteins mutS family
UDP-glucose/GDP-mannose dehydrogenase C-terminal
3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold
YbaK/aminoacyl-tRNA synthetase-associated
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Cation-transporting P-type ATPase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Phosphocysteine intermediate; for EIIB activity
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Nitrogenase molybdenum-iron protein beta chain N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
RlpA-like protein double-psi beta-barrel
UDP N-acetylglucosamine O-acyltransferase C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Methionyl-tRNA synthetase anticodon-binding
Polysaccharide chain length determinant N-terminal
SsuA/THI5-like domain-containing protein
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Interaction with polymerase core subunit RpoC
Peptidase S9 prolyl oligopeptidase catalytic
Cytochrome c-type biogenesis protein CcmE
Gp5/Type VI secretion system Vgr protein OB-fold
ABC transporter substrate-binding protein PnrA-like
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Plays an important role in substrate specificity
Prokaryotic-type class I peptide chain release factors
Alpha-(1,3)-fucosyltransferase FucT N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Quercetin 2,3-dioxygenase C-terminal cupin
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Flagellar hook-length control protein-like C-terminal
CobB/CobQ-like glutamine amidotransferase
Prepilin type IV endopeptidase peptidase
Type VI secretion system IcmF C-terminal
Peptidase C14 caspase domain-containing protein
Saccharopine dehydrogenase-like C-terminal
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
S-adenosylmethionine-dependent methyltransferase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Tetrahydrodipicolinate-N-succinyltransferase chain A
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Peptidoglycan binding-like domain-containing protein
Schiff-base intermediate with dihydroxyacetone-P
S-adenosyl-L-homocysteine hydrolase NAD binding
Acyltransferase MbtK/IucB-like conserved
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Important for substrate specificity; cannot use PPi as phosphoryl donor
High-affinity zinc uptake system protein ZnuA
YMGG-like Gly-zipper domain-containing protein
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation