Glycerophosphoryl diester phosphodiesterase membrane
Phosphatidic acid phosphatase type 2/haloperoxidase
Plays an important role in substrate specificity
Translation elongation factor P/YeiP central
Pyrimidine nucleoside phosphorylase C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Major facilitator superfamily (MFS) profile
Aminoacyl-transfer RNA synthetases class-II family profile
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Electron transfer flavoprotein alpha/beta-subunit N-terminal
NIF system FeS cluster assembly NifU N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Could play a key role in the communication between the regulatory and the substrate sites
Large ribosomal subunit protein uL6 alpha-beta
Prokaryotic-type class I peptide chain release factors
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Peptidase S9 prolyl oligopeptidase catalytic
CobB/CobQ-like glutamine amidotransferase
YbaK/aminoacyl-tRNA synthetase-associated
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Bacterial type II secretion system protein E
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Electron transfer flavoprotein alpha subunit C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Pyruvate dehydrogenase E1 component middle
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Polysaccharide biosynthesis protein C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Tryptophan synthase beta chain-like PALP
Glycosyltransferase subfamily 4-like N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Phosphomannose isomerase type I catalytic
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Gram-positive cocci surface proteins LPxTG
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Chromosomal replication initiator DnaA C-terminal
Large ribosomal subunit protein uL2 C-terminal
Prepilin type IV endopeptidase peptidase
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Putative oxidoreductase/dehydrogenase Rossmann-like
Peptidase M1 membrane alanine aminopeptidase
Transposase IS204/IS1001/IS1096/IS1165 DDE
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Cell envelope-related transcriptional attenuator
Gly-cisPro motif, important for rejection of L-amino acids
Alpha-D-phosphohexomutase alpha/beta/alpha
Phosphotransferase system enzyme I N-terminal
Proton acceptor; for glutaminase activity
Formamidopyrimidine-DNA glycosylase catalytic
Schiff-base intermediate with D-ribose 5-phosphate
Large ribosomal subunit protein uL15/eL18
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
6-phosphogluconate dehydrogenase C-terminal
Phosphocysteine intermediate; for EIIB activity
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Polymerase/histidinol phosphatase N-terminal
Pseudouridine synthase I TruA alpha/beta
ABC-type glycine betaine transport system substrate-binding
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Reversibly protonated during proton transport
Pyruvate phosphate dikinase AMP/ATP-binding
Solute-binding protein family 3/N-terminal
Sporulation transcription regulator WhiA N-terminal
Phosphatidate phosphatase APP1 catalytic
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Penicillin-binding protein transpeptidase
Positions MEP for the nucleophilic attack
O-(5'-phospho-DNA)-tyrosine intermediate
RNA 2-O ribose methyltransferase substrate binding
Endonuclease/exonuclease/phosphatase domain-containing protein
Alpha-1,6-glucosidases pullulanase-type C-terminal
Glycoside hydrolase family 13 N-terminal
ABC transporter substrate-binding protein PnrA-like
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Fibrinogen C-terminal domain-containing protein
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Shikimate dehydrogenase substrate binding N-terminal
DNA replication/recombination mediator RecO N-terminal
Peptide methionine sulphoxide reductase MsrA
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Small ribosomal subunit protein uS4 N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Type I restriction modification DNA specificity
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Important for autoinhibition of adenylyltransferase activity
Release factor glutamine methyltransferase N-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Essential for prephenate dehydratase activity
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Thymidylate synthase/dCMP hydroxymethylase
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Membrane fusion protein biotin-lipoyl like
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Schiff-base intermediate with acetaldehyde
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Aminoacyl-tRNA synthetase class I anticodon-binding
tRNA pseudouridylate synthase B C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Membrane iron-sulfur containing protein FtrD-like
UDP-glucose/GDP-mannose dehydrogenase C-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
phosphoenolpyruvate--glycerone phosphotransferase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Alanyl-transfer RNA synthetases family profile
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
RNA polymerase sigma factor 70 region 4 type 2