Interaction with polymerase core subunit RpoC
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Phosphocysteine intermediate; for EIIB activity
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
General stress protein FMN-binding split barrel
Positions MEP for the nucleophilic attack
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Chromosomal replication initiator protein DnaA
Putative aromatic acid exporter C-terminal
Small ribosomal subunit protein uS4 N-terminal
Alpha-glycerophosphate oxidase C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Tryptophan synthase beta chain-like PALP
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Pyridoxamine 5'-phosphate oxidase putative
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Cytochrome oxidase subunit II copper A binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Important for beta-aspartyl-AMP intermediate formation
Cation-transporting P-type ATPase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Large ribosomal subunit protein uL6 alpha-beta
Major facilitator superfamily (MFS) profile
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
YbaK/aminoacyl-tRNA synthetase-associated
Na+-translocating membrane potential-generating system MpsC
Serine aminopeptidase S33 domain-containing protein
Cytochrome b/b6 N-terminal region profile
Glycosyl transferase family 28 C-terminal
Gamma-glutamylcyclotransferase AIG2-like
Aromatic amino acid beta-eliminating lyase/threonine aldolase
tRNA pseudouridylate synthase B C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Phosphotransferase system enzyme I N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Polysaccharide chain length determinant N-terminal
Glycosyltransferase subfamily 4-like N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Transcriptional coactivator p15 (PC4) C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Transposase IS116/IS110/IS902 C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Lantibiotic biosynthesis protein dehydration
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
N6 adenine-specific DNA methyltransferase N-terminal
Heme-copper oxidase subunit III family profile
Gly-cisPro motif, important for rejection of L-amino acids
Type I restriction modification DNA specificity
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Cell envelope-related transcriptional attenuator
Large ribosomal subunit protein uL2 C-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Polysaccharide biosynthesis protein C-terminal
Lactate utilization protein B C-terminal
Alanyl-transfer RNA synthetases family profile
Resolvase/invertase-type recombinase catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
O-(3'-phospho-DNA)-tyrosine intermediate
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Anthranilate synthase component I N-terminal
Neutral/alkaline non-lysosomal ceramidase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Peptide methionine sulphoxide reductase MsrA
Probable transposase IS891/IS1136/IS1341
Important for interaction with partner proteins
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Periplasmic copper-binding protein NosD beta helix
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
O-(5'-phospho-DNA)-tyrosine intermediate
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
ABC transporter substrate-binding protein PnrA-like
ABC transporter substrate-binding protein PnrA-like domain-containing protein
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Cytochrome b/b6 C-terminal region profile
DnaJ homologue subfamily C member 28 conserved
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Gram-positive cocci surface proteins LPxTG
Gram-positive cocci surface proteins LPxTG domain-containing protein
Involved in allosteric activation by GTP
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Inosine/uridine-preferring nucleoside hydrolase
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Type I restriction enzyme R protein N-terminal
Methylguanine DNA methyltransferase ribonuclease-like
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Glycosyltransferase family 28 N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Glycine cleavage T-protein C-terminal barrel
Collagenase ColG-like catalytic helper subdomain
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glutamine ABC transporter substrate-binding protein
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
ABC transporter substrate-binding protein
Transposon Tn7 transposition protein TnsD C-terminal
Transcriptional regulator SgrR N-terminal HTH
Membrane fusion protein biotin-lipoyl like
NIF system FeS cluster assembly NifU C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
L,D-transpeptidase catalytic domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Fe/B12 periplasmic-binding domain-containing protein
Prepilin type IV endopeptidase peptidase
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
Penicillin-binding protein transpeptidase
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Phr family secreted Rap phosphatase inhibitor
Alpha-D-phosphohexomutase alpha/beta/alpha
Membrane insertase YidC/Oxa/ALB C-terminal
Exonuclease VII large subunit C-terminal
Cytochrome C biogenesis protein transmembrane
N(4)-bis(aminopropyl)spermidine synthase C-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Quinolinate phosphoribosyl transferase N-terminal
Schiff-base intermediate with acetaldehyde
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Large ribosomal subunit protein uL15/eL18
Pseudouridine synthase I TruA alpha/beta
Polysaccharide biosynthesis protein CapD-like
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
SUF system FeS cluster assembly SufBD N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Elongation factor G-binding protein N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Peptidase S9 prolyl oligopeptidase catalytic
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Sporulation initiation phosphotransferase B C-terminal
Cytochrome oxidase subunit II transmembrane region profile
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glucosamine/galactosamine-6-phosphate isomerase
Plays an important role in substrate specificity
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Cysteine sulfenic acid (-SOH) intermediate
Tungsten formylmethanofuran dehydrogenase
RND efflux pump membrane fusion protein barrel-sandwich
Release factor glutamine methyltransferase N-terminal
Protective antigen Ca-binding domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Thymidylate synthase/dCMP hydroxymethylase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Putative adhesin domain-containing protein
Putative component of 'biosynthetic module'
RNA binding; important for wobble base 34 recognition
Essential for prephenate dehydratase activity
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Bacterial type II secretion system protein E
serine-type D-Ala-D-Ala carboxypeptidase
Reversibly protonated during proton transport
Bacterial transcription activator effector binding
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Translation elongation factor P/YeiP central
Predicted DNA-binding protein ribbon-helix-helix
DNA-directed DNA polymerase family A palm
Sporulation transcription regulator WhiA N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
6-phosphogluconate dehydrogenase C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Could be important to modulate the pK values of the two catalytic cysteine residues
Peptidoglycan recognition protein family
Ribulose bisphosphate carboxylase large subunit C-terminal
Chromosomal replication initiator DnaA C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Non-canonical purine NTP phosphatase/PRRC1