ABC transporter substrate binding protein
Glycosyltransferase subfamily 4-like N-terminal
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Thiamine pyrophosphate enzyme TPP-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Phosphocysteine intermediate; for EIIB activity
RND efflux pump membrane fusion protein barrel-sandwich
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Thymidylate synthase/dCMP hydroxymethylase
Polymerase/histidinol phosphatase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Tryptophan synthase beta chain-like PALP
ATP synthase F1 complex delta/epsilon subunit N-terminal
DNA mismatch repair proteins mutS family
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glyoxalase/fosfomycin resistance/dioxygenase
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Interaction with polymerase core subunit RpoC
Could be important to modulate the pK values of the two catalytic cysteine residues
Large ribosomal subunit protein bL12 C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Phage terminase large subunit C-terminal
Phage terminase large subunit N-terminal
Bacterial transcription activator effector binding
Cation-transporting P-type ATPase N-terminal
Resolvase/invertase-type recombinase catalytic
Lysidine-tRNA(Ile) synthetase C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Reversibly protonated during proton transport
Bacterial type II secretion system protein E
ABC transporter substrate-binding protein PnrA-like
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Deacetylase PdaC domain-containing protein
Phosphomannose isomerase type I catalytic
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glucose-6-phosphate isomerase prokaryote
Dinitrogenase iron-molybdenum cofactor biosynthesis
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Sporulation stage II protein D amidase enhancer LytB N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Major facilitator superfamily (MFS) profile
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Penicillin-binding protein transpeptidase
Polynucleotide kinase-phosphatase ligase
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Pyruvate phosphate dikinase AMP/ATP-binding
Outer membrane protein beta-barrel domain-containing protein
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 3
Schiff-base intermediate with acetaldehyde
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Phosphatidylglycerol lysyltransferase C-terminal
Putative component of 'biosynthetic module'
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Sporulation transcription regulator WhiA N-terminal
Pseudouridine synthase I TruA alpha/beta
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Essential for prephenate dehydratase activity
RNA 2-O ribose methyltransferase substrate binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Aldehyde ferredoxin oxidoreductase N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Prokaryotic-type class I peptide chain release factors
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Polypeptide-transport-associated ShlB-type
Peptide methionine sulphoxide reductase MsrA
Ribose-phosphate pyrophosphokinase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
O-(5'-phospho-DNA)-tyrosine intermediate
DNA replication/recombination mediator RecO N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Phosphotransferase system enzyme I N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Large ribosomal subunit protein uL15/eL18
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Alanyl-transfer RNA synthetases family profile
Phospholipase D-like domain-containing protein
Quercetin 2,3-dioxygenase C-terminal cupin
Chromosomal replication initiator DnaA C-terminal
Shikimate dehydrogenase substrate binding N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Important for guanine/8-oxoguanine distinction
Flavodoxin-like domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Small ribosomal subunit protein uS4 N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Dihydroorotate dehydrogenase electron transfer subunit iron-sulphur cluster binding
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Choloylglycine hydrolase/NAAA C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Sugar fermentation stimulation protein C-terminal
Positions MEP for the nucleophilic attack
Lysozyme inhibitor LprI N-terminal domain-containing protein
Phosphoribosylformylglycinamidine synthase linker
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Plays an important role in discriminating NADH against NADPH
Survival protein SurE-like phosphatase/nucleotidase
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
YbaK/aminoacyl-tRNA synthetase-associated
Mannose-6-phosphate isomerase type II C-terminal
Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
AB hydrolase-1 domain-containing protein
Inosine/uridine-preferring nucleoside hydrolase
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Cell envelope-related transcriptional attenuator
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Cysteine sulfenic acid (-SOH) intermediate
Peptidase M15C domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Glycosyl hydrolase-like 10 domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
Organic solvent tolerance-like N-terminal
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
TonB-dependent receptor-like beta-barrel
O-(3'-phospho-DNA)-tyrosine intermediate
Prepilin type IV endopeptidase peptidase
Thiamin pyrophosphokinase thiamin-binding
Release factor glutamine methyltransferase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Membrane insertase YidC/Oxa/ALB C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
RNA binding; important for wobble base 34 recognition
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Translation elongation factor P/YeiP central
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
General stress protein FMN-binding split barrel
Large ribosomal subunit protein uL6 alpha-beta
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Large ribosomal subunit protein bL9 C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Phosphotransferase system EIIB component type 2/3
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Autotransporter domain-containing protein
Molybdopterin cofactor biosynthesis C (MoaC)
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Large ribosomal subunit protein uL2 C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Nucleic acid binding OB-fold tRNA/helicase-type
DNA-directed DNA polymerase family A palm
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Outer membrane lipoprotein carrier protein LolA
Gp5/Type VI secretion system Vgr protein OB-fold
Schiff-base intermediate with D-ribose 5-phosphate
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
D-galactose/methyl-galactoside binding periplasmic protein MglB
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Exonuclease VII large subunit C-terminal
CD-NTase associated protein 4-like DNA endonuclease
Plays an important role in substrate specificity
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Polysaccharide biosynthesis protein C-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
MmyB-like transcription regulator ligand binding
Could play a key role in the communication between the regulatory and the substrate sites
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Phage conserved hypothetical protein C-terminal
Large ribosomal subunit protein bL12 oligomerization
Anthranilate synthase component I N-terminal