Penicillin-binding protein transpeptidase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Thiamine pyrophosphate enzyme TPP-binding
O-(5'-phospho-DNA)-tyrosine intermediate
Involved in allosteric activation by GTP
TRAP C4-dicarboxylate transport system permease DctM subunit
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Ribose-phosphate pyrophosphokinase N-terminal
Polysaccharide biosynthesis protein CapD-like
Flagellar Assembly Protein A N-terminal region
Bacterial type II secretion system protein E
Flagellar assembly protein FliH/Type III secretion system HrpE
Pyruvate phosphate dikinase AMP/ATP-binding
YbaK/aminoacyl-tRNA synthetase-associated
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Translation elongation factor P/YeiP central
Phosphomannose isomerase type I catalytic
Shikimate dehydrogenase substrate binding N-terminal
Prokaryotic-type class I peptide chain release factors
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Survival protein SurE-like phosphatase/nucleotidase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Aconitase A/isopropylmalate dehydratase small subunit swivel
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Prepilin type IV endopeptidase peptidase
Aspartate/homoserine dehydrogenase NAD-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Trigger factor ribosome-binding bacterial
Aminoacyl-transfer RNA synthetases class-II family profile
Cell envelope-related transcriptional attenuator
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Diacylglycerol glucosyltransferase N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
S-adenosylmethionine-dependent methyltransferase
ABC transporter substrate-binding protein PnrA-like
Exonuclease VII large subunit C-terminal
DNA mismatch repair proteins mutS family
RNA binding; important for wobble base 34 recognition
Plays an important role in substrate specificity
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Flagellar assembly protein T C-terminal domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Ribosomal RNA small subunit methyltransferase E methyltransferase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glycosyltransferase subfamily 4-like N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Tryptophan synthase beta chain-like PALP
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Essential for prephenate dehydratase activity
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Flagellar motor switch protein FliN-like C-terminal
Magnesium transporter MgtE intracellular
Release factor glutamine methyltransferase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Type I restriction modification DNA specificity
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Ysc84 actin-binding domain-containing protein
Thiamin pyrophosphokinase thiamin-binding
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Organic solvent tolerance-like N-terminal
Alanyl-transfer RNA synthetases family profile
Gly-cisPro motif, important for rejection of L-amino acids
Tripartite tricarboxylate transporter substrate binding protein
NADH-ubiquinone oxidoreductase 51kDa subunit FMN-binding
Schiff-base intermediate with D-ribose 5-phosphate
Pyrimidine nucleoside phosphorylase C-terminal
Polymerase/histidinol phosphatase N-terminal
Sugar fermentation stimulation protein C-terminal
tRNA pseudouridylate synthase B C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
RNA 2-O ribose methyltransferase substrate binding
Pseudouridine synthase I TruA alpha/beta
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
ADP-dependent (S)-NAD(P)H-hydrate dehydratase
Bifunctional NAD(P)H-hydrate repair enzyme Nnr
Major facilitator superfamily (MFS) profile
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Membrane insertase YidC/Oxa/ALB C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
CobB/CobQ-like glutamine amidotransferase
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Small ribosomal subunit protein uS4 N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Ribosomal RNA adenine methylase transferase N-terminal
Cytochrome C biogenesis protein transmembrane
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Large ribosomal subunit protein uL15/eL18
Tryptophan RNA-binding attenuator protein
Septum formation inhibitor MinC C-terminal
Mannose-6-phosphate isomerase type II C-terminal
ATPsynthase alpha/beta subunit N-terminal extension
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
N6 adenine-specific DNA methyltransferase N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
NIF system FeS cluster assembly NifU N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Solute-binding protein family 3/N-terminal
Phosphotransferase system enzyme I N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Involved in ionization of N3 of dUMP, leading to its activation
RlpA-like protein double-psi beta-barrel
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Large ribosomal subunit protein uL6 alpha-beta
Could play a key role in the communication between the regulatory and the substrate sites
Phosphoribosylformylglycinamidine synthase linker
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Molybdopterin cofactor biosynthesis C (MoaC)
Helix-hairpin-helix DNA-binding motif class 1
Could be important to modulate the pK values of the two catalytic cysteine residues
Glycoside hydrolase family 57 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Large ribosomal subunit protein uL2 C-terminal
Energy-coupling factor transporter transmembrane protein EcfT
TonB-dependent receptor-like beta-barrel
Flagellar hook-length control protein-like C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain