NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Important for substrate specificity; cannot use PPi as phosphoryl donor
Transposase IS116/IS110/IS902 C-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
RNA 2-O ribose methyltransferase substrate binding
F420-non-reducing hydrogenase iron-sulfur subunit D
Resolvase/invertase-type recombinase catalytic
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Sodium symporter small subunit predicted
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Nitrite/Sulfite reductase ferredoxin-like
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Glycosyltransferase subfamily 4-like N-terminal
CobB/CobQ-like glutamine amidotransferase
Important for autoinhibition of adenylyltransferase activity
BREX system Lon protease-like BrxL N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
PEP-CTERM protein-sorting domain-containing protein
O-(5'-phospho-DNA)-tyrosine intermediate
Survival protein SurE-like phosphatase/nucleotidase
Phosphotransferase system enzyme I N-terminal
Increases nucleophilicity of active site Cys
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Schiff-base intermediate with D-ribose 5-phosphate
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Type I restriction enzyme R protein N-terminal
Siroheme decarboxylase AsnC-like ligand binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Polysaccharide chain length determinant N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
ATP-dependent DNA helicase RecG C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Chromosomal replication initiator DnaA C-terminal
Involved in allosteric activation by GTP
L-seryl-tRNA selenium transferase N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glucan biosynthesis periplasmic MdoG C-terminal
ABC-type glycine betaine transport system substrate-binding
Lytic transglycosylase superhelical linker
Polymerase/histidinol phosphatase N-terminal
Sulfatase-modifying factor enzyme domain-containing protein
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Aminoacyl-transfer RNA synthetases class-II family profile
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
Bacterial type II secretion system protein E
Transcription factor NikR nickel binding C-terminal
Flagellar motor switch protein FliN-like C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyridine nucleotide-disulphide oxidoreductase dimerisation
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Thiamine pyrophosphate enzyme TPP-binding
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Formamidopyrimidine-DNA glycosylase catalytic
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Reversibly protonated during proton transport
Shikimate dehydrogenase substrate binding N-terminal
Prokaryotic-type class I peptide chain release factors
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Saccharopine dehydrogenase-like C-terminal
ABC transporter substrate binding protein
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Schiff-base intermediate with substrate; via pyruvic acid
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Alpha-D-phosphohexomutase alpha/beta/alpha
Mannose-6-phosphate isomerase type II C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Tryptophan synthase beta chain-like PALP
S-adenosylmethionine-dependent methyltransferase
ABC transporter substrate-binding protein PnrA-like
Interaction with polymerase core subunit RpoC
Flagella basal body P-ring formation protein FlgA C-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Sugar fermentation stimulation protein C-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Major facilitator superfamily (MFS) profile
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
AB hydrolase-1 domain-containing protein
Glycine zipper domain-containing protein
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Aldehyde ferredoxin oxidoreductase N-terminal
Large ribosomal subunit protein uL2 C-terminal
ABC3 transporter permease protein domain-containing protein
Putative regulatory protein FmdB Zinc ribbon
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
AMP-activated protein kinase glycogen-binding
Plays an important role in substrate specificity
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
NADH:ubiquinone oxidoreductase 30kDa subunit
Membrane fusion protein biotin-lipoyl like
nitrite reductase (cytochrome; ammonia-forming)
NIF system FeS cluster assembly NifU N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Outer membrane protein beta-barrel domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
S-adenosyl-L-homocysteine hydrolase NAD binding
Glycine cleavage T-protein C-terminal barrel
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
NIF system FeS cluster assembly NifU C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Penicillin-binding protein transpeptidase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Prepilin type IV endopeptidase peptidase
Outer membrane lipoprotein-sorting protein
tRNA pseudouridylate synthase B C-terminal
N-end rule aminoacyl transferase C-terminal
Glycosyl transferase family 3 N-terminal
Schiff-base intermediate with dihydroxyacetone-P
Ribose 1,5-bisphosphate phosphokinase PhnN
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Phosphatidic acid phosphatase type 2/haloperoxidase
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Alanyl-transfer RNA synthetases family profile
Heme-copper oxidase subunit III family profile
Transglycosylase SLT domain-containing protein
Glucosamine/galactosamine-6-phosphate isomerase
Peptidase metallopeptidase domain-containing protein
Glucose-methanol-choline oxidoreductase N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
O-(3'-phospho-DNA)-tyrosine intermediate
Cysteine sulfenic acid (-SOH) intermediate
Large ribosomal subunit protein uL15/eL18
Glycoside hydrolase family 57 N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
RNA binding; important for wobble base 34 recognition
Phosphatidylglycerol lysyltransferase C-terminal
D-galactarate/Altronate dehydratase C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Conserved virulence factor B-like winged helix
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Ysc84 actin-binding domain-containing protein
Bacterial transcription activator effector binding
Alpha-glycerophosphate oxidase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Trigger factor ribosome-binding bacterial
Transcription elongation factor GreA/GreB N-terminal
Phosphoribosylformylglycinamidine synthase linker
Anthranilate synthase component I N-terminal
Rap1a immunity protein domain-containing protein
Release factor glutamine methyltransferase N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
DnaJ homologue subfamily C member 28 conserved
Heat-inducible transcription repressor HrcA C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Sodium/calcium exchanger membrane region
ATP synthase F1 complex delta/epsilon subunit N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Small ribosomal subunit protein uS4 N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Twin-arginine translocation pathway signal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
DNA replication/recombination mediator RecO N-terminal
Exonuclease VII large subunit C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Could be important to modulate the pK values of the two catalytic cysteine residues
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Polysaccharide biosynthesis protein CapD-like
Translation elongation factor P/YeiP central
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-95)
Important for beta-aspartyl-AMP intermediate formation
DNA-directed DNA polymerase family A palm
Phosphoadenosine phosphosulphate reductase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Extracellular solute-binding protein family 1
6-phosphogluconate dehydrogenase C-terminal
Essential for prephenate dehydratase activity
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Cation-transporting P-type ATPase N-terminal
Thiamin pyrophosphokinase thiamin-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Organic solvent tolerance-like N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Pseudouridine synthase I TruA alpha/beta
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
RNA polymerase sigma factor 70 region 4 type 2
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
DNA mismatch repair proteins mutS family
Outer-membrane lipoprotein carrier protein
Quinohemoprotein amine dehydrogenase alpha subunit haem binding domain-containing protein
Nickel transport complex, NikM subunit, transmembrane
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Pyridoxamine 5'-phosphate oxidase putative
Carbamoyl-phosphate synthase small subunit N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
Flagellar hook-length control protein-like C-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Gly-cisPro motif, important for rejection of L-amino acids
Homocysteine biosynthesis enzyme sulfur-incorporation
Phosphodiester glycosidase domain-containing protein