UDP-glucose/GDP-mannose dehydrogenase C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Penicillin-binding protein transpeptidase
Dienelactone hydrolase domain-containing protein
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Acetylserotonin O-methyltransferase dimerisation
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Could play a key role in the communication between the regulatory and the substrate sites
3-keto-disaccharide hydrolase domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Nitrite/Sulfite reductase ferredoxin-like
Positions MEP for the nucleophilic attack
Could be important to modulate the pK values of the two catalytic cysteine residues
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Major facilitator superfamily (MFS) profile
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Bacterial type II secretion system protein E
Carboxypeptidase regulatory-like domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Heme-copper oxidase subunit III family profile
Tryptophan synthase beta chain-like PALP
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Bacterial bifunctional deaminase-reductase C-terminal
Calcium/calmodulin-dependent protein kinase II association-domain
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Peptidase M1 membrane alanine aminopeptidase
Mu-protocadherin-putative cell-suface protein
Glycosyl hydrolase family 98 carbohydrate binding module
Pyridine nucleotide-disulphide oxidoreductase dimerisation
3-beta hydroxysteroid dehydrogenase/isomerase
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Bacterial spore germination immunoglobulin-like domain-containing protein
Flagellar motor switch protein FliN-like C-terminal
Phosphotransferase system enzyme I N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cytochrome oxidase subunit II copper A binding
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
S-adenosyl-L-homocysteine hydrolase NAD binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
PhoD-like phosphatase metallophosphatase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
RND efflux pump membrane fusion protein barrel-sandwich
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Type I restriction enzyme R protein N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Na+-translocating membrane potential-generating system MpsC
Quercetin 2,3-dioxygenase C-terminal cupin
Carbamoyl-phosphate synthase small subunit N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
6-phosphogluconate dehydrogenase C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Large ribosomal subunit protein uL15/eL18
Translation elongation factor EFTs/EF1B dimerisation
Thiol:disulfide interchange protein DsbD N-terminal
Intracellular proteinase inhibitor BsuPI domain-containing protein
Cation-transporting P-type ATPase N-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Anti-bacteriophage protein A/HamA C-terminal
Chromosomal replication initiator DnaA C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Phosphoribosylformylglycinamidine synthase linker
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Polymerase/histidinol phosphatase N-terminal
Prepilin type IV endopeptidase peptidase
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Helix-hairpin-helix DNA-binding motif class 1
Gly-cisPro motif, important for rejection of L-amino acids
Important for beta-aspartyl-AMP intermediate formation
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Acetyl xylan esterase domain-containing protein
Glycosyl hydrolase family 98 putative carbohydrate-binding module
S-adenosylmethionine-dependent methyltransferase
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Moybdenum cofactor oxidoreductase dimerisation
Molybdopterin cofactor biosynthesis C (MoaC)
Iron dependent repressor metal binding and dimerisation
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
Glycoside hydrolase family 57 N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glycine cleavage T-protein C-terminal barrel
Membrane insertase YidC/Oxa/ALB C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Small ribosomal subunit protein uS4 N-terminal
Cytochrome oxidase subunit II transmembrane region profile
UDP N-acetylglucosamine O-acyltransferase C-terminal
Anthranilate synthase component I N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Membrane fusion protein biotin-lipoyl like
Alanyl-transfer RNA synthetases family profile
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Translation elongation factor P/YeiP central
Type I restriction modification DNA specificity
RNA binding; important for wobble base 34 recognition
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Peptidase MA-like domain-containing protein
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Flagellar hook-length control protein-like C-terminal
Sulfatase-modifying factor enzyme domain-containing protein
Inosine/uridine-preferring nucleoside hydrolase
Sialate O-acetylesterase domain-containing protein
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Release factor glutamine methyltransferase N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Schiff-base intermediate with substrate; via pyruvic acid
Polysaccharide biosynthesis protein CapD-like
tRNA pseudouridylate synthase B C-terminal
ABC-type uncharacterised transport system
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Type II secretion system protein GspG C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Terminase large subunit GpA endonuclease
Putative regulatory protein FmdB Zinc ribbon
Pyruvate phosphate dikinase AMP/ATP-binding
Glyoxalase/fosfomycin resistance/dioxygenase
von Hippel-Lindau disease tumour suppressor beta
Formamidopyrimidine-DNA glycosylase catalytic
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Peptide methionine sulphoxide reductase MsrA
Prokaryotic-type class I peptide chain release factors
ATP-dependent DNA helicase RecG C-terminal
Pseudouridine synthase I TruA alpha/beta
Methylene-tetrahydromethanopterin dehydrogenase N-terminal
Proton acceptor; for glutaminase activity
O-(5'-phospho-DNA)-tyrosine intermediate
DNA replication/recombination mediator RecO N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Endoribonuclease L-PSP/chorismate mutase-like
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
PhoD-like phosphatase metallophosphatase domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Myo-inositol-1-phosphate synthase GAPDH-like
Essential for prephenate dehydratase activity
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Sporulation stage II protein D amidase enhancer LytB N-terminal