Could be important to modulate the pK values of the two catalytic cysteine residues
Tryptophan synthase beta chain-like PALP
Polymerase/histidinol phosphatase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Electron transfer flavoprotein alpha subunit C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
DNA-directed RNA polymerase M/15kDa subunit
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Putative competence-damage inducible protein
UDP-N-acetylmuramoylalanine--D-glutamate ligase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyrroline-5-carboxylate reductase catalytic N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
RNA 2-O ribose methyltransferase substrate binding
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Pyruvate/ketoisovalerate oxidoreductase catalytic
Schiff-base intermediate with D-ribose 5-phosphate
NIF system FeS cluster assembly NifU N-terminal
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Pyridoxal 5'-phosphate synthase subunit PdxT
Membrane fusion protein biotin-lipoyl like
Glutamate synthase alpha subunit C-terminal
Flagellar basal-body/hook protein C-terminal
DNA-directed RNA polymerase subunit alpha
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Glycosyl hydrolase family 30 beta sandwich
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Aminoacyl-transfer RNA synthetases class-II family profile
NADPH-dependent 7-cyano-7-deazaguanine reductase
RlpA-like protein double-psi beta-barrel
RND efflux pump membrane fusion protein barrel-sandwich
Flagellar assembly protein FliH/Type III secretion system HrpE
Putative amidase domain-containing protein
Anthranilate synthase component I N-terminal
Dipicolinate synthase subunit A N-terminal
ABC-type uncharacterised transport system
Thiamine pyrophosphate enzyme TPP-binding
3-isopropylmalate dehydratase small subunit
DNA primase/polymerase bifunctional N-terminal
ATP-dependent DNA helicase RecG C-terminal
Cytochrome C biogenesis protein transmembrane
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Probable transposase IS891/IS1136/IS1341
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamin pyrophosphokinase thiamin-binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Alpha-D-phosphohexomutase alpha/beta/alpha
Major facilitator superfamily (MFS) profile
Penicillin-binding protein transpeptidase
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Probable transcriptional regulatory protein Athe_0816
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Plays an important role in substrate specificity
Bacterial type II secretion system protein E
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Flagellar hook-length control protein-like C-terminal
Bifunctional purine biosynthesis protein PurH
Phosphoribosylformylglycinamidine synthase linker
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Formylmethanofuran dehydrogenase subunit E
Glycosyltransferase subfamily 4-like N-terminal
Transcription regulator AsnC/Lrp ligand binding
Phosphatidylglycerol lysyltransferase C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Flagellar basal body rod protein N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Solute-binding protein family 3/N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
tRNA pseudouridylate synthase B C-terminal
Alanyl-transfer RNA synthetases family profile
Resolvase/invertase-type recombinase catalytic
Important for interaction with partner proteins
Phosphoadenosine phosphosulphate reductase
Flagellar motor switch protein FliN-like C-terminal
Involved in ionization of N3 of dUMP, leading to its activation
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Bifunctional phosphoglucose/phosphomannose isomerase
Holliday junction branch migration complex subunit RuvA
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
NADH-rubredoxin oxidoreductase C-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Signal transduction histidine kinase internal region
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
UDP-N-acetylenolpyruvoylglucosamine reductase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
FMN-dependent NADH:quinone oxidoreductase
Polyribonucleotide nucleotidyltransferase
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Sporulation stage IV protein A C-terminal
Polysaccharide biosynthesis protein C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
3-phosphoshikimate 1-carboxyvinyltransferase
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Lysidine-tRNA(Ile) synthetase C-terminal
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Tryptophan RNA-binding attenuator protein
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit
HicB-like antitoxin of toxin-antitoxin system
Phenylalanine--tRNA ligase alpha subunit
N-acetyl-gamma-glutamyl-phosphate reductase
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
O-(3'-phospho-DNA)-tyrosine intermediate
Septum formation inhibitor MinC C-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
4-hydroxy-tetrahydrodipicolinate synthase
3-methyl-2-oxobutanoate hydroxymethyltransferase
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Important for beta-aspartyl-AMP intermediate formation
Phosphoribosylformylglycinamidine cyclo-ligase
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
ssDNA thymidine ADP-ribosyltransferase DarT
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Interchain (with Cys-216); in linked form
Interchain (with Cys-50); in linked form
Restriction endonuclease type II EcoRII C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
ATP-dependent Clp protease ATP-binding subunit ClpX
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Proton acceptor; for glutaminase activity
Cation-transporting P-type ATPase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Involved in allosteric activation by GTP
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Na+-translocating membrane potential-generating system MpsC
NADH:ubiquinone oxidoreductase 30kDa subunit
Prepilin type IV endopeptidase peptidase
tRNA N6-adenosine threonylcarbamoyltransferase
Glycoside hydrolase family 31 N-terminal
ABC transporter substrate-binding protein PnrA-like
3-isopropylmalate dehydratase large subunit
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
N(4)-bis(aminopropyl)spermidine synthase C-terminal
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Cell envelope-related transcriptional attenuator
ATP-dependent dethiobiotin synthetase BioD
Could play a key role in the communication between the regulatory and the substrate sites
Pyrroline-5-carboxylate reductase dimerisation
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Putative regulatory protein FmdB Zinc ribbon
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Glycoside hydrolase family 42 N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Glutamate-1-semialdehyde 2,1-aminomutase
Mannose-6-phosphate isomerase type II C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
O-(5'-phospho-DNA)-tyrosine intermediate
Holliday junction branch migration complex subunit RuvB
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Ribosomal RNA small subunit methyltransferase G
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Protein O-mannosyl-transferase C-terminal four TM
Reversibly protonated during proton transport
Transcription factor NikR nickel binding C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Glycosyltransferase family 28 N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Ribosomal RNA large subunit methyltransferase H
Flagellar Assembly Protein A N-terminal region
Lantibiotic biosynthesis protein dehydration
Threonine/serine exporter-like N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Conserved hypothetical protein CHP02679 N terminus
Probable nicotinate-nucleotide adenylyltransferase
Chromosomal replication initiator DnaA C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Redox-sensing transcriptional repressor Rex
Involved in Mg(2+) ion dislocation from EF-Tu
Carbamoyl-phosphate synthase small subunit N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Release factor glutamine methyltransferase N-terminal
Sodium/calcium exchanger membrane region
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)