Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Right handed beta helix domain-containing protein
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Gp5/Type VI secretion system Vgr protein OB-fold
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Bacterial type II secretion system protein E
Aminoacyl-transfer RNA synthetases class-II family profile
Important for substrate specificity; cannot use PPi as phosphoryl donor
Peptidase M1 membrane alanine aminopeptidase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Key residue in conferring substrate specificity for N-acetyl-L-ornithine versus N-succinyl-L-ornithine
Outer membrane protein beta-barrel domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
RNA polymerase sigma factor 70 region 4 type 2
Tryptophan synthase beta chain-like PALP
Mechanosensitive ion channel protein MscS
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Myo-inositol-1-phosphate synthase GAPDH-like
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Pectate lyase superfamily protein domain-containing protein
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Gfo/Idh/MocA-like oxidoreductase N-terminal
Peptidase C-terminal archaeal/bacterial domain-containing protein
Polysaccharide biosynthesis protein C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
O-(5'-phospho-DNA)-tyrosine intermediate
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
S-adenosyl-L-homocysteine hydrolase NAD binding
Large ribosomal subunit protein uL2 C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
IgGFc-binding protein N-terminal domain-containing protein
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Tail specific protease domain-containing protein
Major facilitator superfamily (MFS) profile
Formamidopyrimidine-DNA glycosylase catalytic
Blue (type 1) copper domain-containing protein
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Translation elongation factor EFTs/EF1B dimerisation
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Serine aminopeptidase S33 domain-containing protein
Carbohydrate-binding domain-containing protein
Bacterial bifunctional deaminase-reductase C-terminal
Copper type II ascorbate-dependent monooxygenase C-terminal domain-containing protein
RNA 2-O ribose methyltransferase substrate binding
RND efflux pump membrane fusion protein barrel-sandwich
Pyruvate phosphate dikinase AMP/ATP-binding
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Sulfatase-modifying factor enzyme domain-containing protein
Glycoside hydrolase family 57 N-terminal
ssDNA thymidine ADP-ribosyltransferase DarT
Cytochrome oxidase subunit II copper A binding
Tetrahydrodipicolinate-N-succinyltransferase chain A
4Fe-4S ferredoxin-type domain-containing protein
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
SGNH hydrolase-type esterase domain-containing protein
Large ribosomal subunit protein uL15/eL18
Histidine-specific methyltransferase SAM-dependent
Transglutaminase-like domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Signal transduction histidine kinase internal region
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
TonB-dependent receptor-like beta-barrel
Could be important to modulate the pK values of the two catalytic cysteine residues
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Copper type II ascorbate-dependent monooxygenase C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Outer membrane lipoprotein carrier protein LolA
Outer membrane lipoprotein BamD-like domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Cation-transporting P-type ATPase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Abnormal spindle-like microcephaly-associated protein ASH domain-containing protein
Schiff-base intermediate with dihydroxyacetone-P
Extensin-like C-terminal domain-containing protein
Hydrazine synthase alpha subunit middle domain-containing protein
Aminoacyl-tRNA synthetase class II (D/K/N)
Carboxypeptidase regulatory-like domain-containing protein
Glycosyltransferase family 28 N-terminal
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
2-oxoacid dehydrogenase acyltransferase catalytic
Type II secretion system protein GspG C-terminal
Penicillin-binding protein transpeptidase
Glycosyl hydrolase family 32 N-terminal domain-containing protein
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
AB hydrolase-1 domain-containing protein
Aldehyde ferredoxin oxidoreductase N-terminal
Alginate export domain-containing protein
Cytochrome c-552/4 domain-containing protein
Glycosyl hydrolase family 13 catalytic domain-containing protein
Release factor glutamine methyltransferase N-terminal
Trigger factor ribosome-binding bacterial
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Pyridoxamine 5'-phosphate oxidase putative
Poly (ADP-ribose) glycohydrolase (PARG) catalytic
Proton acceptor; for glutaminase activity
Acyltransferase MbtK/IucB-like conserved
Phosphatidate phosphatase APP1 catalytic
Prepilin type IV endopeptidase peptidase
Predicted DNA-binding protein ribbon-helix-helix
ABC transporter substrate-binding protein PnrA-like
Tle cognate immunity protein 4 C-terminal
Mannose-6-phosphate isomerase type II C-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Heat-inducible transcription repressor HrcA C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Pseudouridine synthase I TruA alpha/beta
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Peptidase M43 pregnancy-associated plasma-A
Peptidase M43 pregnancy-associated plasma-A domain-containing protein
Phosphoadenosine phosphosulphate reductase
Peptidase M6-like domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Heme-copper oxidase subunit III family profile
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Chalcone isomerase domain-containing protein
Glycoside hydrolase family 5 domain-containing protein
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Methyltransferase domain-containing protein
Type II secretion system protein GspE N-terminal
Glycosyltransferase RgtA/B/C/D-like domain-containing protein
Translation elongation factor P/YeiP central
PsrA tetracyclin repressor-like C-terminal
Membrane fusion protein biotin-lipoyl like
RNA 3'-terminal phosphate cyclase insert
ABC-type uncharacterised transport system
Chitin-binding type-2 domain-containing protein
S-adenosylmethionine-dependent methyltransferase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Ribosomal RNA small subunit methyltransferase E methyltransferase
Na+/H+ antiporter MnhB subunit-related protein
N-(5'-phosphoribosyl)anthranilate isomerase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
YbaK/aminoacyl-tRNA synthetase-associated
Periplasmic copper-binding protein NosD beta helix
Metallopeptidase domain-containing protein
EcxA zinc-binding domain-containing protein
Gfo/Idh/MocA-like oxidoreductase C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Peptidase M16 C-terminal domain-containing protein
SMODS-associated and fused to various effectors
Polymerase/histidinol phosphatase N-terminal domain-containing protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Conserved virulence factor B-like winged helix
Dickkopf N-terminal cysteine-rich domain-containing protein
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Fibronectin type-III domain-containing protein
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
EfeO-type cupredoxin-like domain-containing protein
Tc toxin complex TcA C-terminal TcB-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Copper acquisition factor BIM1-like domain-containing protein
Glycine cleavage T-protein C-terminal barrel
O-(phosphoribosyl dephospho-coenzyme A)serine
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Peptide-N-glycosidase F C-terminal domain-containing protein
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Peptidase M17 leucyl aminopeptidase N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Alpha-2-macroglobulin domain-containing protein
Metallo-beta-lactamase domain-containing protein
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Survival protein SurE-like phosphatase/nucleotidase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
NIF system FeS cluster assembly NifU N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
L,D-transpeptidase catalytic domain-containing protein
PilC beta-propeller domain-containing protein
Small ribosomal subunit protein uS4 N-terminal
DNA replication/recombination mediator RecO N-terminal
Peptide methionine sulphoxide reductase MsrA
Insecticide toxin TcdB middle/C-terminal
Insecticide toxin TcdB middle/N-terminal
Penicillin-binding protein activator LpoB
Ribose-phosphate pyrophosphokinase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Prokaryotic-type class I peptide chain release factors
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Autotransporter domain-containing protein
Interaction with polymerase core subunit RpoC
Copper type II ascorbate-dependent monooxygenase N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Phosphatidylglycerol lysyltransferase C-terminal
TonB C-terminal domain-containing protein
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
DNA-directed DNA polymerase family A palm
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Serine/threonine specific protein phosphatases
Cytochrome oxidase subunit II transmembrane region profile
Vitamin K epoxide reductase domain-containing protein
Bacterial virulence factor lipase N-terminal domain-containing protein
Superoxide dismutase copper/zinc binding
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Thiosulphate:quinone oxidoreductase small subunit DoxA
Sulfatase N-terminal domain-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Transcription factor NikR nickel binding C-terminal
Thiopeptide-type bacteriocin biosynthesis
Aconitase A/isopropylmalate dehydratase small subunit swivel
Homogentisate 1,2-dioxygenase N-terminal
DNA mismatch repair proteins mutS family
AgmX/PglI C-terminal domain-containing protein
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Adaptive response protein AidB N-terminal
Loss of aminomutase activity and increased product racemization. Gain of ammonia-lyase activity.
Loss of aminomutase and ammonia-lyase activity.
Loss of aminomutase and ammonia-lyase activity. Higher enantiomeric excess of (R)-beta-tyrosine.
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Transcription elongation factor GreA/GreB N-terminal
Plays an important role in substrate specificity
Type VI secretion system IcmF C-terminal