Penicillin-binding protein transpeptidase
Alpha-D-phosphohexomutase alpha/beta/alpha
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Aminoacyl-transfer RNA synthetases class-II family profile
Gram-positive cocci surface proteins LPxTG
Gram-positive cocci surface proteins LPxTG domain-containing protein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
DNA replication/recombination mediator RecO N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Resolvase/invertase-type recombinase catalytic
Sporulation transcription regulator WhiA N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Pseudouridine synthase I TruA alpha/beta
Thymidylate synthase/dCMP hydroxymethylase
Membrane insertase YidC/Oxa/ALB C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Phosphoribosylformylglycinamidine synthase linker
Bacterial type II secretion system protein E
Transcriptional coactivator p15 (PC4) C-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
DNA-directed RNA polymerase RpoA/D/Rpb3-type
RNA binding; important for wobble base 34 recognition
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Interaction with polymerase core subunit RpoC
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Reversibly protonated during proton transport
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
CobB/CobQ-like glutamine amidotransferase
Schiff-base intermediate with acetaldehyde
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Gfo/Idh/MocA-like oxidoreductase N-terminal
Polysaccharide biosynthesis protein CapD-like
Phosphocysteine intermediate; for EIIB activity
Solute-binding protein family 3/N-terminal
NIF system FeS cluster assembly NifU N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Prokaryotic-type class I peptide chain release factors
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Aspartate/homoserine dehydrogenase NAD-binding
Glucosamine/galactosamine-6-phosphate isomerase
Cation-transporting P-type ATPase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
DNA mismatch repair proteins mutS family
Ribose-phosphate pyrophosphokinase N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Major facilitator superfamily (MFS) profile
ATP synthase F1 complex delta/epsilon subunit N-terminal
DNA-directed DNA polymerase family A palm
Polymerase/histidinol phosphatase N-terminal
Tryptophan synthase beta chain-like PALP
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
6-phosphogluconate dehydrogenase C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Alpha-glycerophosphate oxidase C-terminal
Cell envelope-related transcriptional attenuator
Chromosomal replication initiator DnaA C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glycosyltransferase subfamily 4-like N-terminal
Plays an important role in substrate specificity
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
O-(5'-phospho-DNA)-tyrosine intermediate
Involved in allosteric activation by GTP
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Choloylglycine hydrolase/NAAA C-terminal
Threonine/serine exporter-like N-terminal
Phosphomannose isomerase type I catalytic
Important for beta-aspartyl-AMP intermediate formation
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Alanyl-transfer RNA synthetases family profile
Conserved virulence factor B-like winged helix
ABC-type glycine betaine transport system substrate-binding
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Carbamoyl-phosphate synthase small subunit N-terminal
Small ribosomal subunit protein uS4 N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Polysaccharide biosynthesis protein C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Polysaccharide chain length determinant N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Phosphatidic acid phosphatase type 2/haloperoxidase
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Translation elongation factor P/YeiP central
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Sugar ABC transporter substrate-binding protein
Putative aromatic acid exporter C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Shikimate dehydrogenase substrate binding N-terminal
Thiamin pyrophosphokinase thiamin-binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Exonuclease VII large subunit C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Important for interaction with partner proteins
PsbP C-terminal domain-containing protein
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Type VII secretion system protein EssD-like
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
M protein trans-acting positive regulator (MGA) HTH
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
SUF system FeS cluster assembly SufBD N-terminal
Release factor glutamine methyltransferase N-terminal
Menaquinone biosynthesis protein MenD middle
YbaK/aminoacyl-tRNA synthetase-associated
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Helix-hairpin-helix DNA-binding motif class 1
Mandelate racemase/muconate lactonizing enzyme C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
ABC transporter substrate-binding protein PnrA-like
Phosphotransferase system enzyme I N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
S-adenosylmethionine-dependent methyltransferase
tRNA pseudouridylate synthase B C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Cell division protein FtsQ/DivIB C-terminal