Methylene-tetrahydrofolate reductase C-terminal
D-galactarate/Altronate dehydratase C-terminal
Thiamin pyrophosphokinase thiamin-binding
Glycosyltransferase subfamily 4-like N-terminal
N-acetyl-gamma-glutamyl-phosphate reductase
Heat-inducible transcription repressor HrcA C-terminal
Thiamine pyrophosphate enzyme TPP-binding
Trigger factor ribosome-binding bacterial
Cation-transporting P-type ATPase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
O-(3'-phospho-DNA)-tyrosine intermediate
Chromosomal replication initiator DnaA C-terminal
Anthranilate synthase component I N-terminal
Prepilin type IV endopeptidase peptidase
Sugar fermentation stimulation protein C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Glycoside-hydrolase family GH114 TIM-barrel
Cobalamin-independent methionine synthase MetE N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Involved in allosteric activation by GTP
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Penicillin-binding protein transpeptidase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
Glycoside hydrolase family 57 N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Major facilitator superfamily (MFS) profile
Tryptophan synthase beta chain-like PALP
Pyruvate phosphate dikinase AMP/ATP-binding
Bacterial type II secretion system protein E
Polymerase/histidinol phosphatase N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Glycoside hydrolase family 31 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Membrane insertase YidC/Oxa/ALB C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Sigma 54 modulation/S30EA ribosomal protein C-terminal
RNA binding; important for wobble base 34 recognition
Cell envelope-related transcriptional attenuator
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Sodium/calcium exchanger membrane region
Glycoside hydrolase family 42 N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
RNA 2-O ribose methyltransferase substrate binding
Putative regulatory protein FmdB Zinc ribbon
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
RNA polymerase sigma factor 70 region 4 type 2
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Protein-L-isoaspartate O-methyltransferase
Alanyl-transfer RNA synthetases family profile
ADP-dependent (S)-NAD(P)H-hydrate dehydratase
Bifunctional NAD(P)H-hydrate repair enzyme Nnr
Carbamoyl-phosphate synthase small subunit N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Schiff-base intermediate with acetaldehyde
Interaction with polymerase core subunit RpoC
DNA mismatch repair proteins mutS family
DNA-directed DNA polymerase family A palm
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Homocysteine biosynthesis enzyme sulfur-incorporation
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Pyridoxal 5'-phosphate synthase subunit PdxS
Schiff-base intermediate with D-ribose 5-phosphate
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO
Probable nicotinate-nucleotide adenylyltransferase
Damage-control phosphatase ARMT1-like metal-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
3-beta hydroxysteroid dehydrogenase/isomerase
4-hydroxy-tetrahydrodipicolinate reductase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
NIF system FeS cluster assembly NifU N-terminal
DNA-directed RNA polymerase subunit omega
Phosphodiester glycosidase domain-containing protein
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
S-adenosyl-L-homocysteine hydrolase NAD binding
Plays an important role in substrate specificity
DNA-directed RNA polymerase RpoA/D/Rpb3-type
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
NfeD-like C-terminal domain-containing protein
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Probable glycine dehydrogenase (decarboxylating) subunit 1
ABC transporter substrate-binding protein PnrA-like
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Probable 6-oxopurine nucleoside phosphorylase
Type II secretion system protein GspG C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
6-phosphogluconate dehydrogenase C-terminal
Crossover junction endodeoxyribonuclease RuvC
O-(5'-phospho-DNA)-tyrosine intermediate
Gly-cisPro motif, important for rejection of L-amino acids
Involved in ionization of N3 of dUMP, leading to its activation
TRAP C4-dicarboxylate transport system permease DctM subunit
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Probable transcriptional regulatory protein Dtur_1615
Polysaccharide chain length determinant N-terminal
tRNA N6-adenosine threonylcarbamoyltransferase
Imidazole glycerol phosphate synthase subunit HisF
Sporulation stage II protein D amidase enhancer LytB N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Reversibly protonated during proton transport
Quinolinate phosphoribosyl transferase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Survival protein SurE-like phosphatase/nucleotidase
Ribosomal RNA large subunit methyltransferase H
Mannose-6-phosphate isomerase type II C-terminal
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
RND efflux pump membrane fusion protein barrel-sandwich
1,4-alpha-glucan branching enzyme C-terminal
Important for guanine/8-oxoguanine distinction
CobB/CobQ-like glutamine amidotransferase
Probable septum site-determining protein MinC
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
ATP-dependent Clp protease ATP-binding subunit ClpX
Essential for prephenate dehydratase activity
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Inner membrane protein YgaP-like transmembrane
Pyrimidine nucleoside phosphorylase C-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Probable dual-specificity RNA methyltransferase RlmN
Type II secretion system protein GspE N-terminal
5-methylthioadenosine/S-adenosylhomocysteine deaminase
Transcription antitermination protein NusB
Phenylalanine--tRNA ligase alpha subunit
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Pyridoxal 5'-phosphate synthase subunit PdxT
Aconitase A/isopropylmalate dehydratase small subunit swivel
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Ribose-phosphate pyrophosphokinase N-terminal
Methylaspartate ammonia-lyase C-terminal
Methylaspartate ammonia-lyase N-terminal
Proton acceptor; for glutaminase activity
Peptidase M1 membrane alanine aminopeptidase
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Glycine cleavage T-protein C-terminal barrel
NADH-rubredoxin oxidoreductase C-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Positions MEP for the nucleophilic attack
Ribosomal RNA small subunit methyltransferase H
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Large ribosomal subunit protein uL15/eL18
Cysteine sulfenic acid (-SOH) intermediate
Interchain (with Cys-219); in linked form
Interchain (with Cys-52); in linked form
Phosphoribosylformylglycinamidine synthase linker
HPr(Ser) kinase/phosphorylase N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Deoxyuridine 5'-triphosphate nucleotidohydrolase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
ATP synthase F1 complex delta/epsilon subunit N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Polyribonucleotide nucleotidyltransferase
Membrane fusion protein biotin-lipoyl like
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
DNA replication/recombination mediator RecO N-terminal
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor