Glycosyl hydrolase family 13 catalytic domain-containing protein
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Transition state stabilizer; via amide nitrogen
SGNH hydrolase-type esterase domain-containing protein
Glycosyltransferase subfamily 4-like N-terminal
Type IX secretion system membrane protein PorP/SprF
Ribose-phosphate pyrophosphokinase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
TonB-dependent receptor-like beta-barrel
Phosphatidic acid phosphatase type 2/haloperoxidase
Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Tryptophan synthase beta chain-like PALP
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Outer membrane protein beta-barrel domain-containing protein
Peptidase M1 membrane alanine aminopeptidase
3-keto-disaccharide hydrolase domain-containing protein
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Heme-copper oxidase subunit III family profile
Xylose isomerase-like TIM barrel domain-containing protein
Large ribosomal subunit protein uL15/eL18
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Major facilitator superfamily (MFS) profile
Important for beta-aspartyl-AMP intermediate formation
Molybdopterin cofactor biosynthesis C (MoaC)
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
RND efflux pump membrane fusion protein barrel-sandwich
Non-canonical purine NTP phosphatase/PRRC1
SusC/RagA family TonB-linked outer membrane protein
Peptide methionine sulphoxide reductase MsrA
Resolvase/invertase-type recombinase catalytic
Conserved virulence factor B-like winged helix
Polysaccharide chain length determinant N-terminal
Arabinogalactan endo-beta-1,4-galactanase
Peptidase S9 prolyl oligopeptidase catalytic
Histidine-specific methyltransferase SAM-dependent
4'-phosphopantetheinyl transferase N-terminal
Plays an important role in discriminating NADH against NADPH
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Transglutaminase-like domain-containing protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Phosphoadenosine phosphosulphate reductase
Prokaryotic glutathione synthetase ATP-binding
ATP-grasp fold succinyl-CoA synthetase-type
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Haem-binding uptake Tiki superfamily ChaN
DNA mismatch repair proteins mutS family
N-acetyltransferase domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Large ribosomal subunit protein uL2 C-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Alanyl-transfer RNA synthetases family profile
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Lysidine-tRNA(Ile) synthetase C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Lipocalin-like domain-containing protein
Toxin-antitoxin system YwqK family antitoxin
YbaK/aminoacyl-tRNA synthetase-associated
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Type I restriction modification DNA specificity
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Pseudouridine synthase I TruA alpha/beta
O-(3'-phospho-DNA)-tyrosine intermediate
Myo-inositol-1-phosphate synthase GAPDH-like
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Calcineurin-like phosphoesterase domain-containing protein
Glycosyl transferase family 3 N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Thiamine pyrophosphate enzyme TPP-binding
Homogentisate 1,2-dioxygenase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Secretion system C-terminal sorting domain-containing protein
SusD/RagB family nutrient-binding outer membrane lipoprotein
Nitrite/Sulfite reductase ferredoxin-like
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Putative oxidoreductase/dehydrogenase Rossmann-like
Bacterial surface antigen (D15) domain-containing protein
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Beta-lactamase class A catalytic domain-containing protein
Peptidase M14 carboxypeptidase A domain-containing protein
Peptide methionine sulfoxide reductase MsrA
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Helix-hairpin-helix DNA-binding motif class 1
Trigger factor ribosome-binding bacterial
Glucosamine/galactosamine-6-phosphate isomerase
NADH-rubredoxin oxidoreductase C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Polymerase/histidinol phosphatase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
DNA replication/recombination mediator RecO N-terminal
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Reversibly protonated during proton transport
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Glucose/Sorbosone dehydrogenase domain-containing protein
Schiff-base intermediate with substrate; via pyruvic acid
Thrombospondin type 3 repeat-containing protein
Cation-transporting P-type ATPase N-terminal
Heavy metal binding domain-containing protein
Quercetin 2,3-dioxygenase C-terminal cupin
Biopterin-dependent aromatic amino acid hydroxylase family profile
Abnormal spindle-like microcephaly-associated protein ASH domain-containing protein
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Acetyl xylan esterase domain-containing protein
Penicillin-binding protein transpeptidase
Polysaccharide biosynthesis protein C-terminal
Plays an important role in maintaining the position of the catalytic nucleophile
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
CD-NTase associated protein 4-like DNA endonuclease
Could be important to modulate the pK values of the two catalytic cysteine residues
Glycosyl-hydrolase 97 C-terminal oligomerisation
Cupin 2 conserved barrel domain-containing protein
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Proteinase inhibitor I42 chagasin domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
tRNA pseudouridylate synthase B C-terminal
RagB/SusD family nutrient uptake outer membrane protein
Chromosomal replication initiator DnaA C-terminal
Glycine cleavage T-protein C-terminal barrel
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Type IX secretion system protein PorV domain-containing protein
Sodium/calcium exchanger membrane region
Ribosomal RNA adenine methylase transferase N-terminal
Beta-hexosaminidase bacterial type N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Pyrroline-5-carboxylate reductase catalytic N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Proton acceptor; for glutaminase activity
Peptidase S8/S53 domain-containing protein
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Glycine zipper domain-containing protein
TonB-dependent receptor plug domain-containing protein
Membrane fusion protein biotin-lipoyl like
PhoD-like phosphatase metallophosphatase
Survival protein SurE-like phosphatase/nucleotidase
ABC-type uncharacterised transport system
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
T9SS C-terminal target domain-containing protein
N,N-dimethylformamidase beta subunit-like C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Iron dependent repressor metal binding and dimerisation
TonB-dependent receptor-like beta-barrel domain-containing protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
Type 1 periplasmic binding fold superfamily protein
Translation elongation factor P/YeiP central
Anthranilate synthase component I N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Nucleophile; cysteine thiosulfonate intermediate
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Phosphoribosylformylglycinamidine synthase linker
N6 adenine-specific DNA methyltransferase N-terminal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Anti-bacteriophage protein A/HamA C-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Type I restriction enzyme R protein N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Small ribosomal subunit protein uS4 N-terminal
ssDNA thymidine ADP-ribosyltransferase DarT
NIF system FeS cluster assembly NifU N-terminal
Integral membrane protein YccS N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Gylcosyl hydrolase 115 C-terminal domain-containing protein
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
TonB C-terminal domain-containing protein
SusE outer membrane protein domain-containing protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
NADH:ubiquinone oxidoreductase chain 4 N-terminal
DNA-directed DNA polymerase family A palm
General stress protein FMN-binding split barrel
NADH:ubiquinone oxidoreductase 30kDa subunit
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Pyrroline-5-carboxylate reductase dimerisation
Formamidopyrimidine-DNA glycosylase catalytic
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
DNA topoisomerase I catalytic core eukaryotic-type
Release factor glutamine methyltransferase N-terminal
Signal transduction histidine kinase internal region
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Metallo-beta-lactamase domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Aromatic hydrocarbon degradation protein
ATP synthase F1 complex delta/epsilon subunit N-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
RNA binding; important for wobble base 34 recognition
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
S-adenosylmethionine-dependent methyltransferase
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Surface glycan-binding protein B xyloglucan binding
Surface glycan-binding protein B xyloglucan binding domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Large ribosomal subunit protein uL6 alpha-beta
Antitoxin Xre/MbcA/ParS-like toxin-binding
Saccharopine dehydrogenase-like C-terminal
RNA 2-O ribose methyltransferase substrate binding
Translation elongation factor EFTs/EF1B dimerisation
Cysteine sulfenic acid (-SOH) intermediate
UDP N-acetylglucosamine O-acyltransferase C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Gliding motility-associated C-terminal domain-containing protein
Alpha galactosidase C-terminal beta sandwich
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Plays an important role in substrate specificity
Activator of Hsp90 ATPase homologue 1-like C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
NIF system FeS cluster assembly NifU C-terminal
Chitobiase/beta-hexosaminidases N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Prokaryotic-type class I peptide chain release factors
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A