NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Major facilitator superfamily (MFS) profile
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Bacterial transcription activator effector binding
Peptidase S9 prolyl oligopeptidase catalytic
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Transcription regulator AsnC/Lrp ligand binding
Flagellar Assembly Protein A N-terminal region
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Membrane insertase YidC/Oxa/ALB C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Molybdopterin cofactor biosynthesis C (MoaC)
Alanyl-transfer RNA synthetases family profile
Resolvase/invertase-type recombinase catalytic
RNA polymerase sigma factor 70 region 4 type 2
Cytochrome C biogenesis protein transmembrane
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Polymerase/histidinol phosphatase N-terminal
Membrane fusion protein biotin-lipoyl like
RND efflux pump membrane fusion protein barrel-sandwich
Cytochrome oxidase subunit II copper A binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Solute-binding protein family 3/N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Glycine cleavage T-protein C-terminal barrel
Reversibly protonated during proton transport
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
DNA-directed DNA polymerase family A palm
Involved in allosteric activation by GTP
Polysaccharide biosynthesis protein C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Glycosyl transferase family 3 N-terminal
ABC-type glycine betaine transport system substrate-binding
Transposase IS116/IS110/IS902 C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Activator of Hsp90 ATPase homologue 1-like C-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Threonine/serine exporter-like N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Cell envelope-related transcriptional attenuator
Interaction with polymerase core subunit RpoC
Schiff-base intermediate with D-ribose 5-phosphate
O-(3'-phospho-DNA)-tyrosine intermediate
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Pseudouridine synthase I TruA alpha/beta
Na+-translocating membrane potential-generating system MpsC
Phosphoribosylformylglycinamidine synthase linker
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Flagellar motor switch protein FliN-like C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Bacterial EndoU nuclease domain-containing protein
DNA mismatch repair proteins mutS family
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Survival protein SurE-like phosphatase/nucleotidase
Glucosamine/galactosamine-6-phosphate isomerase
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Sporulation stage IV protein A C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
ABC transporter substrate-binding protein PnrA-like
Prepilin type IV endopeptidase peptidase
SMODS-associated and fused to various effectors
Penicillin-binding protein transpeptidase
Tryptophan synthase beta chain-like PALP
Sodium/calcium exchanger membrane region
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Pyridoxamine 5'-phosphate oxidase putative
Cytochrome b/b6 N-terminal region profile
Thiamin pyrophosphokinase thiamin-binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
NIF system FeS cluster assembly NifU N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Pyrimidine nucleoside phosphorylase C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Ionotropic glutamate receptor C-terminal
DNA replication/recombination mediator RecO N-terminal
tRNA pseudouridylate synthase B C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Anthranilate synthase component I N-terminal
Transcriptional regulator LacI/GalR-like sensor
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
RNA 2-O ribose methyltransferase substrate binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Glycosyltransferase subfamily 4-like N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Cytochrome oxidase subunit II transmembrane region profile
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Diacylglycerol glucosyltransferase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Chromosomal replication initiator DnaA C-terminal
DNA-3-methyladenine glycosylase AlkA N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Urease accessory protein UreH-like transmembrane
Cysteine sulfenic acid (-SOH) intermediate
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Large ribosomal subunit protein uL2 C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Small ribosomal subunit protein uS4 N-terminal
Non-canonical purine NTP phosphatase/PRRC1
Cell wall-active antibiotics response LiaF-like C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Signal recognition particle SRP54 helical bundle
Release factor glutamine methyltransferase N-terminal
Bacterial type II secretion system protein E
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Ribonucleotide reductase large subunit C-terminal
Superoxide dismutase copper/zinc binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Essential for prephenate dehydratase activity
Glyoxalase/fosfomycin resistance/dioxygenase
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Alpha-glycerophosphate oxidase C-terminal
Putative Flp pilus-assembly TadG-like N-terminal
Magnesium transporter MgtE intracellular
Cation-transporting P-type ATPase N-terminal
Septum formation inhibitor MinC C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
N6 adenine-specific DNA methyltransferase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Heme-copper oxidase subunit III family profile
Formamidopyrimidine-DNA glycosylase catalytic
Ribosomal RNA adenine methylase transferase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Type I restriction modification DNA specificity
Phosphocysteine intermediate; for EIIB activity
Bacterial spore germination immunoglobulin-like
Translation elongation factor P/YeiP central
Helix-hairpin-helix DNA-binding motif class 1
Inosine/uridine-preferring nucleoside hydrolase
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Gamma-glutamylcyclotransferase AIG2-like
Important for interaction with partner proteins
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Methylguanine DNA methyltransferase ribonuclease-like
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
NIF system FeS cluster assembly NifU C-terminal
Saccharopine dehydrogenase-like C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Transcriptional regulator SgrR N-terminal HTH
Sporulation stage II protein D amidase enhancer LytB N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Schiff-base intermediate with acetaldehyde
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Large ribosomal subunit protein bL9 C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Cytochrome b/b6 C-terminal region profile
DNA polymerase III delta subunit C-terminal
Sporulation initiation phosphotransferase B C-terminal
Polysaccharide chain length determinant N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Peptidase M1 membrane alanine aminopeptidase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Dipicolinate synthase subunit A N-terminal
Large ribosomal subunit protein uL15/eL18
NADH:ubiquinone oxidoreductase 30kDa subunit
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
SUF system FeS cluster assembly SufBD N-terminal
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein uL6 alpha-beta
S-adenosyl-L-homocysteine hydrolase NAD binding
D-arabinono-1,4-lactone oxidase C-terminal
Copper amine oxidase-like N-terminal domain-containing protein
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Tryptophan RNA-binding attenuator protein
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Peptidase M17 leucyl aminopeptidase N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Sporulation transcription regulator WhiA N-terminal
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
3-beta hydroxysteroid dehydrogenase/isomerase
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
6-phosphogluconate dehydrogenase C-terminal
Ger(X)C family spore germination protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Flagellar hook-length control protein-like C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Phosphotransferase system enzyme I N-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Exonuclease VII large subunit C-terminal