Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Sodium/calcium exchanger membrane region
RND efflux pump membrane fusion protein barrel-sandwich
TrbL/VirB6 plasmid conjugal transfer protein
Cytochrome C biogenesis protein transmembrane
Outer membrane lipoprotein carrier protein LolA
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
SUF system FeS cluster assembly SufBD N-terminal
Thiamine pyrophosphate enzyme TPP-binding
Alpha-D-phosphohexomutase alpha/beta/alpha
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Heat-inducible transcription repressor HrcA C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Penicillin-binding protein transpeptidase
NAD(P) transhydrogenase alpha subunit C-terminal
Polymerase/histidinol phosphatase N-terminal
Peptide methionine sulphoxide reductase MsrA
Interacts with tRNA; defines subfamily-specific binding signature
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Ribosomal RNA adenine methylase transferase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
YbaK/aminoacyl-tRNA synthetase-associated
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
DNA primase/polymerase bifunctional N-terminal
RNA binding; important for wobble base 34 recognition
Major facilitator superfamily (MFS) profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Transcription regulator AsnC/Lrp ligand binding
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Prokaryotic-type class I peptide chain release factors
DNA replication/recombination mediator RecO N-terminal
Type 4 fimbrial biogenesis protein PilX N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Inosine/uridine-preferring nucleoside hydrolase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Peptidase S9 prolyl oligopeptidase catalytic
TRAP C4-dicarboxylate transport system permease DctM subunit
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Anthranilate synthase component I N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
RNA 2-O ribose methyltransferase substrate binding
Bacterial type II secretion system protein E
Water stress and hypersensitive response domain-containing protein
Aspartate/homoserine dehydrogenase NAD-binding
Outer membrane lipoprotein-sorting protein
N6 adenine-specific DNA methyltransferase N-terminal
ABC transporter substrate-binding protein PnrA-like
Glycoside hydrolase family 31 N-terminal
Kanamycin nucleotidyltransferase C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
O-(5'-phospho-DNA)-tyrosine intermediate
NADH:flavin oxidoreductase/NADH oxidase N-terminal
NfeD-like C-terminal domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Large ribosomal subunit protein uL6 alpha-beta
Aconitase A/isopropylmalate dehydratase small subunit swivel
Bacterial bifunctional deaminase-reductase C-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Alanyl-transfer RNA synthetases family profile
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
NADH:ubiquinone oxidoreductase 30kDa subunit
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Tryptophan synthase beta chain-like PALP
Tripartite tricarboxylate transporter substrate binding protein
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Small ribosomal subunit protein uS4 N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Essential for prephenate dehydratase activity
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Outer membrane protein beta-barrel domain-containing protein
Gamma-glutamylcyclotransferase AIG2-like
C-type lysozyme inhibitor domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
N-end rule aminoacyl transferase C-terminal
Large ribosomal subunit protein uL15/eL18
Inner membrane protein YgaP-like transmembrane
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Arginine decarboxylase C-terminal helical
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Thiamin pyrophosphokinase thiamin-binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Moybdenum cofactor oxidoreductase dimerisation
Prepilin type IV endopeptidase peptidase
CRISPR system ring nuclease SSO1393-like
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Non-canonical purine NTP phosphatase/PRRC1
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Large ribosomal subunit protein uL2 C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
ABC-type glycine betaine transport system substrate-binding
Membrane fusion protein biotin-lipoyl like
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Sodium symporter small subunit predicted
Ribose-phosphate pyrophosphokinase N-terminal
Na+/H+ antiporter MnhB subunit-related protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
UDP-glucose/GDP-mannose dehydrogenase C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Nitrite/Sulfite reductase ferredoxin-like
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Electron transfer via tryptophanyl radical
Cation-transporting P-type ATPase N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Phosphoribosylformylglycinamidine synthase linker
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Cell envelope-related transcriptional attenuator
Translation elongation factor P/YeiP central
Positions MEP for the nucleophilic attack
Type I restriction modification DNA specificity
Glycoside-hydrolase family GH114 TIM-barrel
Gly-cisPro motif, important for rejection of L-amino acids
Organic solvent tolerance-like N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Survival protein SurE-like phosphatase/nucleotidase
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
RNA polymerase sigma factor 70 region 4 type 2
Helix-hairpin-helix DNA-binding motif class 1
Pyruvate dehydrogenase E1 component middle
Plays an important role in substrate specificity
Important for interaction with partner proteins
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
DNA mismatch repair proteins mutS family
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Could play a key role in the communication between the regulatory and the substrate sites
Copper amine oxidase-like N-terminal domain-containing protein
Type III restriction enzyme C-terminal endonuclease
Carbamoyl-phosphate synthase small subunit N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Glycosyl transferase family 3 N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase C-terminal
Trigger factor ribosome-binding bacterial
20-fold decrease in synthesis of ATP from AMP. 7-fold decrease in synthesis of ATP from ADP.
6-fold decrease in synthesis of ATP from AMP.
AMP/ADP-polyphosphate phosphotransferase
Flavocytochrome c sulphide dehydrogenase flavin-binding
Glycosyltransferase family 28 N-terminal
Phosphomannose isomerase type I catalytic
Cytochrome c-type biogenesis protein CcmF C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Bacterial transcription activator effector binding
Glycine cleavage T-protein C-terminal barrel
Carboxypeptidase regulatory-like domain-containing protein
Schiff-base intermediate with D-ribose 5-phosphate
Terminase large subunit gp17-like C-terminal
Glycoside hydrolase family 42 N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
DNA-directed RNA polymerase RpoA/D/Rpb3-type
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
D-galactarate/Altronate dehydratase C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Septum formation inhibitor MinC C-terminal
Release factor glutamine methyltransferase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
S-adenosylmethionine-dependent methyltransferase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
CRISPR-associated protein Cas6 C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Probable transposase IS891/IS1136/IS1341
Putative glycogen debranching enzyme N-terminal
Adaptive response protein AidB N-terminal
Alpha-glycerophosphate oxidase C-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Lactate utilization protein B C-terminal
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Thymidylate synthase/dCMP hydroxymethylase