Major facilitator superfamily (MFS) profile
Gamma-glutamylcyclotransferase AIG2-like
Aminoacyl-transfer RNA synthetases class-II family profile
Glycosyltransferase subfamily 4-like N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
PBS lyase HEAT domain protein repeat-containing protein
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Phosphatidylglycerol lysyltransferase C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Adaptive response protein AidB N-terminal
TonB-dependent receptor-like beta-barrel
UDP-glucose/GDP-mannose dehydrogenase C-terminal
ABC-type uncharacterised transport system
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
AMP-activated protein kinase glycogen-binding
Bacterial microcompartment protein trimer-3
Transcription elongation factor GreA/GreB C-terminal
DNA-directed DNA polymerase family A palm
Pyridoxamine 5'-phosphate oxidase putative
Gp5/Type VI secretion system Vgr protein OB-fold
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Cysteine sulfenic acid (-SOH) intermediate
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Outer membrane protein beta-barrel domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Proton acceptor; for glutaminase activity
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Anthranilate synthase component I N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Penicillin-binding protein transpeptidase
Transcription elongation factor GreA/GreB N-terminal
Release factor glutamine methyltransferase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Periplasmic copper-binding protein NosD beta helix
Acyl-CoA dehydrogenase/oxidase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Phosphocysteine intermediate; for EIIB activity
Peptidase S8/S53 domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
General stress protein FMN-binding split barrel
Tryptophan synthase beta chain-like PALP
Aconitase A/isopropylmalate dehydratase small subunit swivel
Ribosomal RNA small subunit methyltransferase E methyltransferase
Could play a key role in the communication between the regulatory and the substrate sites
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Bacterial microcompartment protein homohexamer
Forms larger hexamer patches, increases hexamer stacking.
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
3-beta hydroxysteroid dehydrogenase/isomerase
Pyrimidine nucleoside phosphorylase C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Butirosin biosynthesis protein H N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Outer membrane beta-barrel domain-containing protein
Chitobiase/beta-hexosaminidases N-terminal
Thiopeptide-type bacteriocin biosynthesis
Alpha-D-phosphohexomutase alpha/beta/alpha
Ribose-phosphate pyrophosphokinase N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Contractile injection system tube protein N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Type II secretion system protein GspE N-terminal
Bacterial microcompartment protein trimer-1
Binds a 4Fe-4S cluster, exposed on the concave face.
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Bacterial bifunctional deaminase-reductase C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
DNA topoisomerase I catalytic core eukaryotic-type
Resolvase/invertase-type recombinase catalytic
SMODS-associated and fused to various effectors
Conserved hypothetical protein CHP02679 N terminus
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
NIF system FeS cluster assembly NifU N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Predicted DNA-binding protein ribbon-helix-helix
Could be important to modulate the pK values of the two catalytic cysteine residues
Peptidase S9 prolyl oligopeptidase catalytic
Bacterial microcompartment shell vertex protein
Peptidase M1 membrane alanine aminopeptidase
Putative adhesin domain-containing protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
YbaK/aminoacyl-tRNA synthetase-associated
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Penicillin-insensitive murein endopeptidase
Cell wall-active antibiotics response LiaF-like C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Large ribosomal subunit protein uL6 alpha-beta
Sporulation stage II protein D amidase enhancer LytB N-terminal
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Phosphatidate phosphatase APP1 catalytic
Polysaccharide biosynthesis protein C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Transition state stabilizer; via amide nitrogen
Putative oxidoreductase/dehydrogenase Rossmann-like
Inward rectifier potassium channel C-terminal
Na+/H+ antiporter MnhB subunit-related protein
Glycosyl transferase family 3 N-terminal
Small ribosomal subunit protein uS4 N-terminal
Bacterial type II secretion system protein E
Cytochrome c7-like domain-containing protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Insecticide toxin TcdB middle/N-terminal
Polysaccharide biosynthesis protein CapD-like
RND efflux pump membrane fusion protein barrel-sandwich
Histidine-specific methyltransferase SAM-dependent
4'-phosphopantetheinyl transferase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
ABC transporter substrate-binding protein PnrA-like
Nitrite/Sulfite reductase ferredoxin-like
Tetrahydrodipicolinate-N-succinyltransferase chain A
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Methionyl-tRNA synthetase anticodon-binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
N6 adenine-specific DNA methyltransferase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
S-adenosylmethionine-dependent methyltransferase
Cation-transporting P-type ATPase N-terminal
Phosphotransferase system enzyme I N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Prokaryotic-type class I peptide chain release factors
Cytochrome C Planctomycete-type domain-containing protein
DNA replication/recombination mediator RecO N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Phosphoribosylformylglycinamidine synthase linker
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Ribosomal RNA adenine methylase transferase N-terminal
PhoD-like phosphatase metallophosphatase
NADH:ubiquinone oxidoreductase-like 20kDa subunit
TRAP C4-dicarboxylate transport system permease DctM subunit
Sodium/calcium exchanger membrane region
Phosphoadenosine phosphosulphate reductase
Phosphomannose isomerase type I catalytic
SGNH hydrolase-type esterase domain-containing protein
Heme-copper oxidase subunit III family profile
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Phosphatidic acid phosphatase type 2/haloperoxidase
RNA 3'-terminal phosphate cyclase insert
Cytochrome c-552/4 domain-containing protein
RNA binding; important for wobble base 34 recognition
Polysaccharide chain length determinant N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Plays an important role in substrate specificity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
S-adenosyl-L-homocysteine hydrolase NAD binding
Helix-hairpin-helix DNA-binding motif class 1
Cytochrome c-type biogenesis protein CcmF C-terminal
Glycosyl hydrolase family 30 beta sandwich
ABC-type glycine betaine transport system substrate-binding
Type I restriction modification DNA specificity
Doubled CXXCH motif domain-containing protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Pseudouridine synthase I TruA alpha/beta
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
RlpA-like protein double-psi beta-barrel
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
TonB-dependent receptor-like beta-barrel domain-containing protein
O-(5'-phospho-DNA)-tyrosine intermediate
Trigger factor ribosome-binding bacterial
Lysidine-tRNA(Ile) synthetase C-terminal
Glycine cleavage T-protein C-terminal barrel
Peptidase M17 leucyl aminopeptidase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Putative regulatory protein FmdB Zinc ribbon
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Large ribosomal subunit protein uL2 C-terminal
Zinc-regulated TonB-dependent outer membrane receptor
Formamidopyrimidine-DNA glycosylase catalytic
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Type II secretion system protein GspC N-terminal
Microcin J25-processing protein McjB C-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Cytochrome P460 domain-containing protein
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Flagellar assembly protein T N-terminal domain-containing protein
SUF system FeS cluster assembly SufBD N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Gfo/Idh/MocA-like oxidoreductase C-terminal
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
NADH:ubiquinone oxidoreductase 30kDa subunit
Sigma 54 modulation/S30EA ribosomal protein C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Prepilin type IV endopeptidase peptidase
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Acetylserotonin O-methyltransferase dimerisation
Essential for prephenate dehydratase activity
Translation elongation factor P/YeiP central
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Alanyl-transfer RNA synthetases family profile
Diacylglycerol glucosyltransferase N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Carbamoyl-phosphate synthase small subunit N-terminal
Bacterial microcompartment protein trimer-2
Extensin-like C-terminal domain-containing protein
Gly-cisPro motif, important for rejection of L-amino acids
Saccharopine dehydrogenase-like C-terminal
Bacterial transcription activator effector binding
Important for interaction with partner proteins
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Arginine decarboxylase C-terminal helical
Tat (Twin-arginine translocation) pathway signal sequence domain protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Membrane fusion protein biotin-lipoyl like
Thymidylate synthase/dCMP hydroxymethylase
Cytochrome oxidase subunit II copper A binding
Important for beta-aspartyl-AMP intermediate formation