Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
TonB-dependent receptor-like beta-barrel
Small ribosomal subunit protein uS4 N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
RNA polymerase sigma factor 70 region 4 type 2
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
6-phosphogluconate dehydrogenase C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Tryptophan synthase beta chain-like PALP
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Plays an important role in substrate specificity
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Bacterial type II secretion system protein E
Replication initiation protein-like C-terminal
Major facilitator superfamily (MFS) profile
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
N6 adenine-specific DNA methyltransferase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Pyruvate/ketoisovalerate oxidoreductase catalytic
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
RNA 2-O ribose methyltransferase substrate binding
Integral membrane protein YccS N-terminal
Reversibly protonated during proton transport
General stress protein FMN-binding split barrel
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Interacts with tRNA; defines subfamily-specific binding signature
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Alpha-D-phosphohexomutase alpha/beta/alpha
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Arginine decarboxylase C-terminal helical
Glycosyltransferase family 28 N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Large ribosomal subunit protein uL2 C-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Flagellar assembly protein FliH/Type III secretion system HrpE
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Key residue in conferring substrate specificity for N-acetyl-L-ornithine versus N-succinyl-L-ornithine
NADH:ubiquinone oxidoreductase 30kDa subunit
NADH:ubiquinone oxidoreductase-like 20kDa subunit
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Prepilin type IV endopeptidase peptidase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
O-(5'-phospho-DNA)-tyrosine intermediate
Pyridine nucleotide-disulphide oxidoreductase dimerisation
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Interaction with polymerase core subunit RpoC
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
N-end rule aminoacyl transferase C-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Proton acceptor; for glutaminase activity
Translation elongation factor P/YeiP central
Thymidylate synthase/dCMP hydroxymethylase
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Lysidine-tRNA(Ile) synthetase C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Glycine zipper 2TM domain-containing protein
Phosphoethanolamine transferase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
RND efflux pump membrane fusion protein barrel-sandwich
Peptidase S9 prolyl oligopeptidase catalytic
Schiff-base intermediate with substrate; via pyruvic acid
Essential for prephenate dehydratase activity
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Membrane fusion protein biotin-lipoyl like
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Trigger factor ribosome-binding bacterial
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Could be important to modulate the pK values of the two catalytic cysteine residues
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Aminoacyl-transfer RNA synthetases class-II family profile
Anthranilate synthase component I N-terminal
Type I restriction modification DNA specificity
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Carbohydrate-binding/sugar hydrolysis domain-containing protein
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Heme-copper oxidase subunit III family profile
DNA-directed DNA polymerase family A palm
Flagellar motor switch protein FliN-like C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Thiol:disulfide interchange protein DsbA
O-(phosphoribosyl dephospho-coenzyme A)serine
Flagella basal body P-ring formation protein FlgA
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Polymerase/histidinol phosphatase N-terminal
Type II secretion system protein GspG C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Cysteine sulfenic acid (-SOH) intermediate
Polysaccharide biosynthesis protein CapD-like
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Phosphotransferase system enzyme I N-terminal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Aspartate/homoserine dehydrogenase NAD-binding
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
DNA replication/recombination mediator RecO N-terminal
Alpha-glycerophosphate oxidase C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Glutathionylspermidine synthase pre-ATP-grasp-like
Chromosomal replication initiator DnaA C-terminal
Translocation and assembly module subunit TamA
RNA binding; important for wobble base 34 recognition
Tetrahydrodipicolinate-N-succinyltransferase chain A
Superoxide dismutase copper/zinc binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Penicillin-binding protein transpeptidase
Mannose-6-phosphate isomerase type II C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Large ribosomal subunit protein uL6 alpha-beta
Prokaryotic-type class I peptide chain release factors
Glycosyltransferase subfamily 4-like N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Beta-hexosaminidase bacterial type N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Ribosomal RNA adenine methylase transferase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glycosyl transferase family 28 C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
ATP synthase F1 complex delta/epsilon subunit N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Proline utilization A proline dehydrogenase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Exonuclease VII large subunit C-terminal
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-92)
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
ABC-type transport auxiliary lipoprotein component
Pseudouridine synthase I TruA alpha/beta
3-beta hydroxysteroid dehydrogenase/isomerase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Threonine/serine exporter-like N-terminal
Large ribosomal subunit protein uL15/eL18
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Lytic transglycosylase superhelical linker
Important for beta-aspartyl-AMP intermediate formation
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Release factor glutamine methyltransferase N-terminal
Important for interaction with partner proteins
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
UDP N-acetylglucosamine O-acyltransferase C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Histidine-specific methyltransferase SAM-dependent
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Flagellar hook-length control protein-like C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
O-(3'-phospho-DNA)-tyrosine intermediate
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Putative beta-barrel assembly-enhancing protease
Late embryogenesis abundant protein LEA-2 subgroup
Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein
Acyl-CoA dehydrogenase C-terminal bacterial-type
Gp5/Type VI secretion system Vgr protein OB-fold
Biopterin-dependent aromatic amino acid hydroxylase family profile
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Pyruvate dehydrogenase E1 component middle
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
PHA accumulation regulator DNA-binding N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Peptide methionine sulphoxide reductase MsrA
S-adenosyl-L-homocysteine hydrolase NAD binding
Regulator of nucleoside diphosphate kinase N-terminal
Type VI secretion system IcmF C-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Alanyl-transfer RNA synthetases family profile