RNA polymerase sigma factor 70 region 4 type 2
Aminoacyl-transfer RNA synthetases class-II family profile
Peptidase S9 prolyl oligopeptidase catalytic
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Alpha-N-acetylglucosaminidase C-terminal
Alpha-N-acetylglucosaminidase N-terminal
Alpha-N-acetylglucosaminidase tim-barrel
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Important for catalytic activity against all substrates
Important for catalytic activity against dermatan sulfate substrate
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
TonB-dependent receptor-like beta-barrel
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Inner membrane protein YgaP-like transmembrane
Large ribosomal subunit protein bL9 C-terminal
Major facilitator superfamily (MFS) profile
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
ATP synthase F1 complex delta/epsilon subunit N-terminal
Release factor glutamine methyltransferase N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Aconitase A/isopropylmalate dehydratase small subunit swivel
Ribosomal RNA adenine methylase transferase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Beta-hexosaminidase bacterial type N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Positions MEP for the nucleophilic attack
Outer membrane protein beta-barrel domain-containing protein
SUF system FeS cluster assembly SufBD N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Acetyl xylan esterase domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Bacterial surface antigen (D15) domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Auto-transporter adhesin head GIN domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Large ribosomal subunit protein uL2 C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Gliding motility-associated lipoprotein GldD
Signal transduction histidine kinase internal region
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Peptidase M1 membrane alanine aminopeptidase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
NIF system FeS cluster assembly NifU N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Glycoamylase-like domain-containing protein
Heme-copper oxidase subunit III family profile
Penicillin-binding protein transpeptidase
Aspartate/homoserine dehydrogenase NAD-binding
Schiff-base intermediate with substrate; via pyruvic acid
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Heparinase II N-terminal domain-containing protein
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Electron transfer via tryptophanyl radical
NlpE C-terminal OB domain-containing protein
Polysaccharide lyase 8 N-terminal alpha-helical
Polysaccharide lyase family 8 C-terminal
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Pectate lyase superfamily protein domain-containing protein
Glycosyltransferase subfamily 4-like N-terminal
Phosphatidate phosphatase APP1 catalytic
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Prokaryotic-type class I peptide chain release factors
Cell envelope-related transcriptional attenuator
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Lipocalin-like domain-containing protein
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Bacterial transcription activator effector binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Pseudouridine synthase I TruA alpha/beta
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Thiol:disulfide interchange protein DsbD N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Polysaccharide chain length determinant N-terminal
Cytochrome c-type biogenesis protein CcmE
Polysaccharide biosynthesis protein C-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Chromosomal replication initiator DnaA C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glycine cleavage T-protein C-terminal barrel
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
DNA topoisomerase I catalytic core eukaryotic-type
Gliding motility associated protein GldN
O-(3'-phospho-DNA)-tyrosine intermediate
Nickel transport complex, NikM subunit, transmembrane
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glycosyl-hydrolase 97 C-terminal oligomerisation
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Carbamoyl-phosphate synthase small subunit N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Neutral/alkaline non-lysosomal ceramidase N-terminal domain-containing protein
3-keto-disaccharide hydrolase domain-containing protein
Integral membrane protein YccS N-terminal
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
ABC-type uncharacterised transport system
Glycoside hydrolase family 2 catalytic domain-containing protein
Carboxypeptidase-like regulatory domain-containing protein
Type IX secretion system protein PorV domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
DNA-directed DNA polymerase family A palm
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Polymerase/histidinol phosphatase N-terminal
tRNA pseudouridylate synthase B C-terminal
Right handed beta helix domain-containing protein
Secretion system C-terminal sorting domain-containing protein
tRNA1(Val) (adenine(37)-N6)-methyltransferase
Alpha glucuronidase N-terminal domain-containing protein
Sulfatase-modifying factor enzyme domain-containing protein
UDP N-acetylglucosamine O-acyltransferase C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Small ribosomal subunit protein uS4 N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Beta-xylosidase C-terminal Concanavalin A-like
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Alpha-glycerophosphate oxidase C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Formamidopyrimidine-DNA glycosylase catalytic
Carboxypeptidase regulatory-like domain-containing protein
Cellulose-binding Sde182 nucleoside hydrolase-like
Bacterial bifunctional deaminase-reductase C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
S-adenosyl-L-homocysteine hydrolase NAD binding
Transcription elongation factor GreA/GreB C-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Alpha-(1,3)-fucosyltransferase FucT N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Sialate O-acetylesterase domain-containing protein
Transcription elongation factor GreA/GreB N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Glycoside hydrolase family 31 N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
TonB-dependent receptor-like beta-barrel domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Tryptophan synthase beta chain-like PALP
DNA mismatch repair proteins mutS family
Peptide methionine sulphoxide reductase MsrA
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glycerophosphoryl diester phosphodiesterase
Glycoside hydrolase family 5 domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Polysaccharide biosynthesis protein CapD-like
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Xylose isomerase domain protein TIM barrel
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
ATP-dependent exodnase (Exonuclease V) alpha subunit-helicase superfamily I member
Cytochrome C biogenesis protein transmembrane
Glycosyl transferase family 3 N-terminal
Membrane fusion protein biotin-lipoyl like
General stress protein FMN-binding split barrel
Alanyl-transfer RNA synthetases family profile
Glycoside hydrolase family 42 N-terminal
RNA binding; important for wobble base 34 recognition
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Thiopeptide-type bacteriocin biosynthesis
Urease accessory protein UreH-like transmembrane
Proton acceptor; for glutaminase activity
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Gly-cisPro motif, important for rejection of L-amino acids
Thymidylate synthase/dCMP hydroxymethylase
Sodium/calcium exchanger membrane region
Reversibly protonated during proton transport
RNA 2-O ribose methyltransferase substrate binding
Asl1-like glycosyl hydrolase catalytic domain-containing protein
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
6-phosphogluconate dehydrogenase C-terminal
Polysaccharide pyruvyl transferase domain-containing protein
Translation elongation factor P/YeiP central
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
S-adenosylmethionine-dependent methyltransferase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)
Cytochrome c-type biogenesis protein CcmF C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Glycosyl hydrolase-like 10 domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP
N-sulphoglucosamine sulphohydrolase C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Shikimate dehydrogenase substrate binding N-terminal
Glucose/sorbosone dehydrogenase-like protein
Membrane insertase YidC/Oxa/ALB C-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
PBCV-specific basic adaptor domain-containing protein
Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Cationic amino acid transporter C-terminal
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Beta-lactamase class A catalytic domain-containing protein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Mannose-6-phosphate isomerase type II C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Lysidine-tRNA(Ile) synthetase C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Phosphodiester glycosidase domain-containing protein
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
DNA replication/recombination mediator RecO N-terminal
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant domain-containing protein
Plays an important role in discriminating NADH against NADPH
Bacterial type II secretion system protein E
Transglutaminase-like domain-containing protein
Cyclophilin-like domain-containing protein
Type I restriction enzyme R protein N-terminal
NIF system FeS cluster assembly NifU C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Neutral/alkaline non-lysosomal ceramidase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Gliding motility-associated C-terminal domain-containing protein
Alpha galactosidase C-terminal beta sandwich
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Pyruvate phosphate dikinase AMP/ATP-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Plays an important role in substrate specificity
Putative oxidoreductase/dehydrogenase Rossmann-like
Homogentisate 1,2-dioxygenase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Alginate lyase domain-containing protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Glycoside hydrolase 123 N-terminal domain-containing protein
RlpA-like protein double-psi beta-barrel
Large ribosomal subunit protein uL15/eL18
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
YMGG-like Gly-zipper domain-containing protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Trigger factor ribosome-binding bacterial
TonB-dependent receptor plug domain-containing protein