Penicillin-binding protein transpeptidase
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
DNA replication/recombination mediator RecO N-terminal
Putative regulatory protein FmdB Zinc ribbon
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Major facilitator superfamily (MFS) profile
Cytochrome C biogenesis protein transmembrane
Transposase IS204/IS1001/IS1096/IS1165 DDE
RNA polymerase sigma factor 70 region 4 type 2
Resolvase/invertase-type recombinase catalytic
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Glycosyltransferase subfamily 4-like N-terminal
CobB/CobQ-like glutamine amidotransferase
Tryptophan synthase beta chain-like PALP
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Cell envelope-related transcriptional attenuator
Pseudouridine synthase I TruA alpha/beta
Glycine cleavage T-protein C-terminal barrel
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Essential for prephenate dehydratase activity
Heat-inducible transcription repressor HrcA C-terminal
Tetracyclin repressor-like C-terminal group 31
Glucosamine/galactosamine-6-phosphate isomerase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Transglycosylase SLT domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
NADH:ubiquinone oxidoreductase 30kDa subunit
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Molybdopterin cofactor biosynthesis C (MoaC)
Styrene monooxygenase StyA putative substrate binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Glycoside hydrolase family 42 N-terminal
DnaJ homologue subfamily C member 28 conserved
RNA 2-O ribose methyltransferase substrate binding
YbaK/aminoacyl-tRNA synthetase-associated
Aminoacyl-transfer RNA synthetases class-II family profile
Aconitase A/isopropylmalate dehydratase small subunit swivel
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Anthranilate synthase component I N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Microcin J25-processing protein McjB C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Prokaryotic-type class I peptide chain release factors
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Gfo/Idh/MocA-like oxidoreductase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Alpha-D-phosphohexomutase alpha/beta/alpha
Leucine-binding protein domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
SGNH hydrolase-type esterase domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Solute-binding protein family 3/N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Solute-binding protein family 5 domain-containing protein
Formamidopyrimidine-DNA glycosylase catalytic
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Reversibly protonated during proton transport
Plays an important role in substrate specificity
Type VII secretion system protein EssD-like
Membrane insertase YidC/Oxa/ALB C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Cation-transporting P-type ATPase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Transcription regulator AsnC/Lrp ligand binding
Removed in mature form; by autocatalysis
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Cytochrome b/b6 N-terminal region profile
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Prepilin type IV endopeptidase peptidase
Na+/H+ antiporter MnhB subunit-related protein
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Chromosomal replication initiator DnaA C-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Peptide methionine sulphoxide reductase MsrA
O-(3'-phospho-DNA)-tyrosine intermediate
Glycoside hydrolase family 31 N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Protein O-mannosyl-transferase C-terminal four TM
Translation elongation factor P/YeiP central
O-(5'-phospho-DNA)-tyrosine intermediate
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Gram-positive cocci surface proteins LPxTG domain-containing protein
Tetrahydrodipicolinate-N-succinyltransferase chain A
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Bacterial bifunctional deaminase-reductase C-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Helix-hairpin-helix DNA-binding motif class 1
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Large ribosomal subunit protein uL6 alpha-beta
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Phosphomannose isomerase type I catalytic
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
DNA primase/polymerase bifunctional N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
MmyB-like transcription regulator ligand binding
Inosine/uridine-preferring nucleoside hydrolase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Pyrroline-5-carboxylate reductase dimerisation
Phosphatidic acid phosphatase type 2/haloperoxidase
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Thiopeptide-type bacteriocin biosynthesis
Positions MEP for the nucleophilic attack
ABC-type glycine betaine transport system substrate-binding
Large ribosomal subunit protein uL2 C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Nitrite/Sulfite reductase ferredoxin-like
ABC transporter substrate-binding protein
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Fe/B12 periplasmic-binding domain-containing protein
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Gly-cisPro motif, important for rejection of L-amino acids
Bacterial transcription activator effector binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Interaction with polymerase core subunit RpoC
Large ribosomal subunit protein uL15/eL18
6-phosphogluconate dehydrogenase C-terminal
Methylguanine DNA methyltransferase ribonuclease-like
TrbL/VirB6 plasmid conjugal transfer protein
Electron transfer via tryptophanyl radical
Gfo/Idh/MocA-like oxidoreductase C-terminal
Small ribosomal subunit protein uS4 N-terminal
Sodium/calcium exchanger membrane region
Endoribonuclease L-PSP/chorismate mutase-like
ATP synthase F1 complex delta/epsilon subunit N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Methionyl-tRNA synthetase anticodon-binding
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Alanyl-transfer RNA synthetases family profile
PhoD-like phosphatase metallophosphatase
Phosphoribosylformylglycinamidine synthase linker
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Subtilisin inhibitor domain-containing protein
Lactate utilization protein B C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Release factor glutamine methyltransferase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
N-acetylneuraminic acid synthase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Sporulation transcription regulator WhiA N-terminal