NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Large ribosomal subunit protein uL2 C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Essential for prephenate dehydratase activity
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Major facilitator superfamily (MFS) profile
Glycoside hydrolase family 5 domain-containing protein
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Transcription regulator AsnC/Lrp ligand binding
Inosine/uridine-preferring nucleoside hydrolase
Chromosomal replication initiator DnaA C-terminal
Tryptophan synthase beta chain-like PALP
Polymerase/histidinol phosphatase N-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Alanyl-transfer RNA synthetases family profile
Polysaccharide chain length determinant N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Peptidase S9 prolyl oligopeptidase catalytic
Glycoside hydrolase family 31 N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Positions MEP for the nucleophilic attack
Exonuclease VII large subunit C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Quinolinate phosphoribosyl transferase C-terminal
Putative regulatory protein FmdB Zinc ribbon
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
LPXTG-motif cell wall anchor domain protein
AMP-activated protein kinase glycogen-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Resolvase/invertase-type recombinase catalytic
Ribosomal RNA adenine methylase transferase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Aspartate/homoserine dehydrogenase NAD-binding
Helix-hairpin-helix DNA-binding motif class 1
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Aldehyde ferredoxin oxidoreductase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Alpha-glycerophosphate oxidase C-terminal
Moybdenum cofactor oxidoreductase dimerisation
Molybdopterin cofactor biosynthesis C (MoaC)
Peptidoglycan recognition protein family
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
ATP-dependent zinc metalloprotease FtsH 3
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Carbamoyl-phosphate synthase small subunit N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Non-canonical purine NTP phosphatase/PRRC1
Small ribosomal subunit protein uS4 N-terminal
RNA polymerase sigma factor 70 region 4 type 2
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Cell wall-active antibiotics response LiaF-like C-terminal
Putative glycogen debranching enzyme N-terminal
Methionyl-tRNA synthetase anticodon-binding
Glycosyl transferase family 3 N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Polysaccharide biosynthesis protein C-terminal
Penicillin-binding protein transpeptidase
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Phosphotransferase system enzyme I N-terminal
Cytochrome C biogenesis protein transmembrane
Sodium/calcium exchanger membrane region
Putative oxidoreductase/dehydrogenase Rossmann-like
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
ATP-dependent zinc metalloprotease FtsH 1
Cytochrome oxidase subunit II copper A binding
RNA binding; important for wobble base 34 recognition
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
RNA 2-O ribose methyltransferase substrate binding
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Large ribosomal subunit protein uL15/eL18
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Translation elongation factor P/YeiP central
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Flagellar motor switch protein FliN-like C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Activator of Hsp90 ATPase homologue 1-like C-terminal
Trigger factor ribosome-binding bacterial
Peptide methionine sulphoxide reductase MsrA
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
YbaK/aminoacyl-tRNA synthetase-associated
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Cation-transporting P-type ATPase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pseudouridine synthase I TruA alpha/beta
DnaJ homologue subfamily C member 28 conserved
Putative Flp pilus-assembly TadG-like N-terminal
Restriction system protein Mrr-like N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Heat-inducible transcription repressor HrcA C-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
DNA-directed DNA polymerase family A palm
Mannose-6-phosphate isomerase type II C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Heme-copper oxidase subunit III family profile
Pyruvate phosphate dikinase AMP/ATP-binding
Glucosamine/galactosamine-6-phosphate isomerase
Anthranilate synthase component I N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Alpha-D-phosphohexomutase alpha/beta/alpha
Lysidine-tRNA(Ile) synthetase C-terminal
Menaquinone biosynthesis protein MenD middle
Cell envelope-related transcriptional attenuator
Shal-type voltage-gated potassium channels N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Phosphoribosylformylglycinamidine synthase linker
Membrane insertase YidC/Oxa/ALB C-terminal
Cytochrome oxidase subunit II transmembrane region profile
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Release factor glutamine methyltransferase N-terminal
Prepilin type IV endopeptidase peptidase
Prokaryotic-type class I peptide chain release factors
NAD(P) transhydrogenase alpha subunit C-terminal
Schiff-base intermediate with substrate; via topaquinone
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Flagellar hook-length control protein-like C-terminal
ATP-dependent zinc metalloprotease FtsH 2
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
NIF system FeS cluster assembly NifU N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Extracellular solute-binding protein family 1
6-phosphogluconate dehydrogenase C-terminal
UDP-glucose/GDP-mannose dehydrogenase N-terminal
UDP-glucose/GDP-mannose dehydrogenase dimerisation
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Myo-inositol-1-phosphate synthase GAPDH-like
Type I restriction modification DNA specificity
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Squalene cyclase C-terminal domain-containing protein
EfeO-type cupredoxin-like domain-containing protein
Terminase large subunit gp17-like C-terminal
Nucleophile or transition state stabilizer
Queuosine 5'-phosphate N-glycosylase/hydrolase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
NfeD-like C-terminal domain-containing protein
DNA primase/polymerase bifunctional N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Bacterial type II secretion system protein E
Gly-cisPro motif, important for rejection of L-amino acids
Sigma 54 modulation/S30EA ribosomal protein C-terminal
ABC-type glycine betaine transport system substrate-binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
DNA replication/recombination mediator RecO N-terminal
Carboxypeptidase regulatory-like domain-containing protein
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
S-adenosyl-L-homocysteine hydrolase NAD binding
DNA mismatch repair proteins mutS family
Mandelate racemase/muconate lactonizing enzyme C-terminal
Type ISP restriction-modification enzyme LLaBIII C-terminal specificity
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Could be important to modulate the pK values of the two catalytic cysteine residues
Large ribosomal subunit protein uL30-like ferredoxin-like fold
CobB/CobQ-like glutamine amidotransferase
Glycoside hydrolase family 57 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Quinolinate phosphoribosyl transferase N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Phosphomannose isomerase type I catalytic
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Acetylserotonin O-methyltransferase dimerisation
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Plays an important role in substrate specificity
Endoribonuclease L-PSP/chorismate mutase-like
Glycine cleavage T-protein C-terminal barrel