Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
RND efflux pump membrane fusion protein barrel-sandwich
Mannose-6-phosphate isomerase type II C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
RNA polymerase sigma factor 70 region 4 type 2
Glycosyl transferase family 3 N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Major facilitator superfamily (MFS) profile
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Acyl-CoA dehydrogenase/oxidase N-terminal
NIF system FeS cluster assembly NifU C-terminal
TonB-dependent receptor-like beta-barrel
Phosphatidylglycerol lysyltransferase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Sodium/calcium exchanger membrane region
NIF system FeS cluster assembly NifU N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Transglycosylase SLT domain-containing protein
Prokaryotic-type class I peptide chain release factors
Acyl-CoA dehydrogenase/oxidase C-terminal
Adaptive response protein AidB N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Siroheme decarboxylase AsnC-like ligand binding
N-end rule aminoacyl transferase C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Alanyl-transfer RNA synthetases family profile
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Release factor glutamine methyltransferase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Flagellar motor switch protein FliN-like C-terminal
PhoD-like phosphatase metallophosphatase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Electron transfer via tryptophanyl radical
Penicillin-binding protein transpeptidase
Glycosyltransferase subfamily 4-like N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Chalcone isomerase domain-containing protein
Quorum-sensing-regulated virulence factor
Gamma-butyrobetaine hydroxylase-like N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Interacts with tRNA; defines subfamily-specific binding signature
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Gamma-glutamylcyclotransferase AIG2-like
Glycoside-hydrolase family GH114 TIM-barrel
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Predicted pPIWI-associating nuclease group 2
Tryptophan synthase beta chain-like PALP
Activator of Hsp90 ATPase homologue 1-like C-terminal
Type II secretion system protein GspI C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Lipoprotein SmpA/OmlA domain-containing protein
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Polypeptide-transport-associated ShlB-type
ShlB/FhaC/HecB family hemolysin secretion/activation protein
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Cytochrome c-type biogenesis protein CcmF C-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
C-type lysozyme inhibitor domain-containing protein
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Putative regulatory protein FmdB Zinc ribbon
Plays an important role in substrate specificity
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Cation-transporting P-type ATPase N-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Shikimate dehydrogenase substrate binding N-terminal
Large ribosomal subunit protein uL6 alpha-beta
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
ABC-type glycine betaine transport system substrate-binding
Cytochrome b561 bacterial/Ni-hydrogenase
Moves into active site upon enzyme activation, plays a role in electron transfer
Membrane fusion protein biotin-lipoyl like
Type VI secretion system IcmF C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Ribose-phosphate pyrophosphokinase N-terminal
Small ribosomal subunit protein uS4 N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Probable periplasmic serine endoprotease DegP-like
Interaction with polymerase core subunit RpoC
Aconitase A/isopropylmalate dehydratase small subunit swivel
Poly-beta-hydroxybutyrate polymerase N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Chromosomal replication initiator DnaA C-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Translation elongation factor P/YeiP central
Divergent polysaccharide deacetylase family protein
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
TonB C-terminal domain-containing protein
Flagellar hook-length control protein-like C-terminal
Prepilin type IV endopeptidase peptidase
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Glycine cleavage T-protein C-terminal barrel
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
Type 4 fimbrial biogenesis protein PilX N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Thiol:disulfide interchange protein DsbD
Type IV methyl-directed restriction enzyme EcoKMcrB subunit DNA-binding
NADH-rubredoxin oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Important for interaction with partner proteins
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Essential for prephenate dehydratase activity
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Acyl-CoA dehydrogenase C-terminal bacterial-type
Peptide methionine sulphoxide reductase MsrA
6-phosphogluconate dehydrogenase C-terminal
DNA polymerase III delta subunit C-terminal
Proline utilization A proline dehydrogenase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Chromosomal replication initiator protein DnaA
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Resolvase/invertase-type recombinase catalytic
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
O-(5'-phospho-DNA)-tyrosine intermediate
Curli production assembly/transport component CsgG
Glucose-methanol-choline oxidoreductase C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Photosynthesis system II assembly factor Ycf48/Hcf136-like
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Inosine/uridine-preferring nucleoside hydrolase
Translocation and assembly module subunit TamA
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein uL15/eL18
Important for autoinhibition of adenylyltransferase activity
Spore coat protein U domain-containing protein
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Urease accessory protein UreH-like transmembrane
Lysozyme inhibitor LprI N-terminal domain-containing protein
Anthranilate synthase component I N-terminal
Alginate export domain-containing protein
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Polymerase/histidinol phosphatase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
DNA polymerase III subunit delta C-terminal
Bacterial type II secretion system protein E
Heme-copper oxidase subunit III family profile
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Peptidase M61 catalytic domain-containing protein
Quercetin 2,3-dioxygenase C-terminal cupin
Pyruvate dehydrogenase E1 component middle
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
Cob(I)alamin adenosyltransferase N-terminal
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Saccharopine dehydrogenase-like C-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
Mandelate racemase/muconate lactonizing enzyme C-terminal
Alpha-glycerophosphate oxidase C-terminal
4'-phosphopantetheinyl transferase N-terminal
Alginate biosynthesis protein AlgX C-terminal carbohydrate-binding module
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Yop protein translocation protein D periplasmic
Thymidylate synthase/dCMP hydroxymethylase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Gp5/Type VI secretion system Vgr protein OB-fold
Bacterial transcription activator effector binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
RNA 2-O ribose methyltransferase substrate binding
Glycine zipper 2TM domain-containing protein
Bacterial bifunctional deaminase-reductase C-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Murein L,D-transpeptidase catalytic domain family protein
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Outer membrane protein assembly factor BamD
Helix-hairpin-helix DNA-binding motif class 1
Mechanosensitive ion channel inner membrane
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Water stress and hypersensitive response
Water stress and hypersensitive response domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Molybdopterin cofactor biosynthesis C (MoaC)
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Important for substrate binding and specificity
Arginine decarboxylase C-terminal helical
Pseudouridine synthase I TruA alpha/beta
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Molybdenum cofactor biosynthesis protein F N-terminal
Glycosyl hydrolases related to GH101 family, GHL1-GHL3
DNA replication/recombination mediator RecO N-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Polysaccharide chain length determinant N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Capsule biosynthesis GfcC-like C-terminal
Capsule biosynthesis GfcC-like N-terminal
Bacterial collagen-like protein middle domain-containing protein
HicB-like antitoxin of toxin-antitoxin system
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Phosphocysteine intermediate; for EIIB activity
Transcription elongation factor GreA/GreB N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Seems to be a necessary countercharge to the potassium cations
Survival protein SurE-like phosphatase/nucleotidase
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
AB hydrolase-1 domain-containing protein
Proton acceptor; for decarboxylase activity
Proton donor; for decarboxylase activity
Proton donor; for formyltransferase activity
Transposase IS204/IS1001/IS1096/IS1165 DDE
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Outer membrane protein assembly factor BamB
Type II secretion system protein GspG C-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Lipoprotein YgdI/YgdR-like SH3-like domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Major facilitator superfamily (MFS) profile domain-containing protein
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Lytic transglycosylase superhelical linker
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Membrane insertase YidC/Oxa/ALB C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Carboxypeptidase regulatory-like domain-containing protein
Inner membrane protein YgaP-like transmembrane
Fimbrial-type adhesion domain-containing protein
NAD(P) transhydrogenase alpha subunit C-terminal
Organic solvent tolerance-like N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Peptidase S9 prolyl oligopeptidase catalytic
Peptide methionine sulfoxide reductase MsrA
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
EfeO-type cupredoxin-like domain-containing protein
DNA topoisomerase I catalytic core eukaryotic-type
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Polyribonucleotide nucleotidyltransferase
S-adenosylmethionine-dependent methyltransferase
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS domain-containing protein
Malonate/sodium symporter MadM subunit N-terminal
DNA-3-methyladenine glycosylase AlkA N-terminal
Solute-binding protein family 5 domain-containing protein
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Involved in tetramerization or stability of the tetramer
Glycoside hydrolase family 42 N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Guanylate kinase/L-type calcium channel beta subunit
DNA-directed DNA polymerase family A palm
Ribosomal RNA adenine methylase transferase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Outer membrane protein assembly factor BamA
Erythronate-4-phosphate dehydrogenase dimerisation
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Required for dimer formation and molybdate binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
O-(3'-phospho-DNA)-tyrosine intermediate
Type II secretion system protein GspC N-terminal
Hypersensitivity response secretion-like HrpJ
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glucosamine/galactosamine-6-phosphate isomerase
YbaK/aminoacyl-tRNA synthetase-associated
For 3-hydroxyacyl-CoA dehydrogenase activity
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Peptidase C-terminal archaeal/bacterial domain-containing protein
DNA mismatch repair proteins mutS family
Outer membrane protein beta-barrel domain-containing protein
Disulphide bond isomerase DsbC/G N-terminal
Large ribosomal subunit protein uL2 C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
L,D-transpeptidase catalytic domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Biotin-protein ligase N-terminal domain-containing protein
Plays an important role in discriminating NADH against NADPH
Lipopolysaccharide export system protein LptA
Integral membrane protein YccS N-terminal
Putative Flp pilus-assembly TadG-like N-terminal
ABC-type uncharacterised transport system
Outer-membrane lipoprotein Wza C-terminal
RNA 3'-terminal phosphate cyclase insert
UDP N-acetylglucosamine O-acyltransferase C-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Sugar fermentation stimulation protein C-terminal
YMGG-like Gly-zipper domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Membrane-bound lytic murein transglycosylase A
Polysaccharide biosynthesis protein CapD-like
Positions MEP for the nucleophilic attack
Ribosomal RNA small subunit methyltransferase E PUA-like
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Outer-membrane lipoprotein carrier protein
NADH:ubiquinone oxidoreductase 30kDa subunit
Exonuclease VII large subunit C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Reversibly protonated during proton transport
Nucleoside-specific outer membrane channel protein Tsx
Putative beta-barrel assembly-enhancing protease
Flagella basal body P-ring formation protein FlgA