TonB-dependent receptor-like beta-barrel
Inward rectifier potassium channel C-terminal
Putative auto-transporter adhesin head GIN
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Beta-lactamase-inhibitor-like, PepSY-like
Glycerophosphoryl diester phosphodiesterase family protein
Xaa-Pro dipeptidyl-peptidase C-terminal domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
NADH:flavin oxidoreductase/NADH oxidase N-terminal
ABC-type uncharacterised transport system
DNA mismatch repair proteins mutS family
Phosphatidic acid phosphatase type 2/haloperoxidase
Alpha-D-phosphohexomutase alpha/beta/alpha
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Polysaccharide biosynthesis protein C-terminal
Signal transduction histidine kinase internal region
Major facilitator superfamily (MFS) profile
Glycosyltransferase subfamily 4-like N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Aminoacyl-transfer RNA synthetases class-II family profile
Chromosomal replication initiator DnaA C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Outer membrane protein beta-barrel domain-containing protein
Polysaccharide biosynthesis protein CapD-like
Peptidase S9 prolyl oligopeptidase catalytic
Activator of Hsp90 ATPase homologue 1-like C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
S-adenosyl-L-homocysteine hydrolase NAD binding
Tryptophan synthase beta chain-like PALP
Positions MEP for the nucleophilic attack
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Bacterial bifunctional deaminase-reductase C-terminal
Collagen triple helix repeat-containing protein
Large ribosomal subunit protein uL2 C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glycoside hydrolase family 31 N-terminal
Type II restriction enzyme and methyltransferase RM.Eco57I-like
RNA binding; important for wobble base 34 recognition
Pseudouridine synthase I TruA alpha/beta
BNR repeat-like domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Trigger factor ribosome-binding bacterial
Pyruvate phosphate dikinase AMP/ATP-binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Phosphoadenosine phosphosulphate reductase
Alpha-glycerophosphate oxidase C-terminal
Outer membrane protein beta-barrel family protein
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Shikimate dehydrogenase substrate binding N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glycosyl transferase family 3 N-terminal
Glycosyl-hydrolase 97 C-terminal oligomerisation
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Thymidylate synthase/dCMP hydroxymethylase
Phosphomannose isomerase type I catalytic
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Peptidase M43 pregnancy-associated plasma-A
Lipocalin-like domain-containing protein
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
RNA 2-O ribose methyltransferase substrate binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Polysaccharide chain length determinant N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Large ribosomal subunit protein bL12 C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
NIF system FeS cluster assembly NifU N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Putative beta-lactamase-inhibitor-like PepSY-like
Transition state stabilizer; via amide nitrogen
DNA replication/recombination mediator RecO N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Tetratricopeptide repeat-containing protein
Type I restriction enzyme R protein N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Conserved virulence factor B-like winged helix
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Type IX secretion system protein PorV domain-containing protein
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Plays an important role in discriminating NADH against NADPH
Tetrahydrodipicolinate-N-succinyltransferase chain A
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Cationic amino acid transporter C-terminal
BAAT / Acyl-CoA thioester hydrolase C terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Polymerase/histidinol phosphatase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Alginate export domain-containing protein
Large ribosomal subunit protein bL9 C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Large ribosomal subunit protein bL12 oligomerization
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Anthranilate synthase component I N-terminal
Prokaryotic-type class I peptide chain release factors
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
CarboxypepD_reg-like domain-containing protein
Release factor glutamine methyltransferase N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Peptidase M1 membrane alanine aminopeptidase
Cell wall-active antibiotics response LiaF-like C-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Helix-hairpin-helix DNA-binding motif class 1
Alanyl-transfer RNA synthetases family profile
Chemotaxis methyl-accepting receptor Tar-related ligand-binding
N-sulphoglucosamine sulphohydrolase C-terminal
Membrane fusion protein biotin-lipoyl like
Lysidine-tRNA(Ile) synthetase C-terminal
TerB family tellurite resistance protein
Gly-cisPro motif, important for rejection of L-amino acids
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Glycoside hydrolase GH146 substrate-binding
Secretion system C-terminal sorting domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
Glucosamine/galactosamine-6-phosphate isomerase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Histidine-specific methyltransferase SAM-dependent
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Alpha galactosidase C-terminal beta sandwich
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
3-keto-disaccharide hydrolase domain-containing protein
Plays an important role in substrate specificity
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Gp5/Type VI secretion system Vgr protein OB-fold
Sphingolipid delta4-desaturase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Insecticide toxin TcdB middle/C-terminal
Insecticide toxin TcdB middle/N-terminal
DNA-binding beta-propeller fold protein YncE
O-(5'-phospho-DNA)-tyrosine intermediate
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Type 2A encapsulin shell protein SrpI-like
Schiff-base intermediate with substrate; via pyruvic acid
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Homogentisate 1,2-dioxygenase N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Type III restriction enzyme C-terminal endonuclease
Organic solvent tolerance-like N-terminal
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Membrane insertase YidC/Oxa/ALB C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
RHS repeat-associated core domain-containing protein
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Urease accessory protein UreH-like transmembrane
Large ribosomal subunit protein uL6 alpha-beta
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Electron transfer via tryptophanyl radical
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Thiopeptide-type bacteriocin biosynthesis
Lysozyme inhibitor LprI N-terminal domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Tc toxin complex TcA C-terminal TcB-binding
Cytochrome c-type biogenesis protein CcmF C-terminal
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Penicillin-binding protein transpeptidase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
ABC-type branched-chain amino acid transport system, substrate-binding protein
Aminoacyl-tRNA synthetase class I anticodon-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Proton acceptor; for glutaminase activity
Heme-copper oxidase subunit III family profile
Pyrroline-5-carboxylate reductase catalytic N-terminal
non-reducing end alpha-L-arabinofuranosidase
DNA-directed DNA polymerase family A palm
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Alpha-2-macroglobulin family N-terminal region
UDP N-acetylglucosamine O-acyltransferase C-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Exonuclease VII large subunit C-terminal
DNA topoisomerase I catalytic core eukaryotic-type
Integral membrane protein YccS N-terminal
Glycoside hydrolase 123 N-terminal domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glycosyl hydrolase family 30 beta sandwich
Small ribosomal subunit protein uS4 N-terminal
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glycine cleavage T-protein C-terminal barrel
Outer membrane protein assembly factor BamA
Survival protein SurE-like phosphatase/nucleotidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Outer membrane lipoprotein-sorting protein
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Type VII secretion system protein EssD-like
Ribosomal RNA adenine methylase transferase N-terminal
Saccharopine dehydrogenase-like C-terminal
Reversibly protonated during proton transport
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Regulation of enolase protein 1, concanavalin A-like superfamily
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Aspartate/homoserine dehydrogenase NAD-binding
Anti-bacteriophage protein A/HamA C-terminal
Pyrroline-5-carboxylate reductase dimerisation
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Formamidopyrimidine-DNA glycosylase catalytic
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Alpha-N-acetylglucosaminidase C-terminal
Alpha-N-acetylglucosaminidase N-terminal
Alpha-N-acetylglucosaminidase tim-barrel
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Cation-transporting P-type ATPase N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Nuclease-associated modular DNA-binding 1
Outer membrane insertion C-terminal signal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Late embryogenesis abundant protein LEA-2 subgroup
Beta-hexosaminidase bacterial type N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Translation elongation factor P/YeiP central
Signal transduction histidine kinase dimerisation/phosphoacceptor