D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Major facilitator superfamily (MFS) profile
Histidine phosphotransferase ChpT C-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Thymidylate synthase/dCMP hydroxymethylase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Magnesium-protoporphyrin IX methyltransferase C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Cytochrome c-type biogenesis protein CcmF C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Amidohydrolase 3 domain-containing protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
TonB-dependent receptor-like beta-barrel
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Tryptophan synthase beta chain-like PALP
Phosphoribosylformylglycinamidine synthase linker
Interaction with polymerase core subunit RpoC
Beta-lactamase-related domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
RNA polymerase sigma factor 70 region 4 type 2
RNA 2-O ribose methyltransferase substrate binding
Polysaccharide chain length determinant N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Membrane fusion protein biotin-lipoyl like
DNA-directed RNA polymerase RpoA/D/Rpb3-type
YbaK/aminoacyl-tRNA synthetase-associated
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Putative Flp pilus-assembly TadG-like N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Galactose-1-phosphate uridyl transferase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Ribose-phosphate pyrophosphokinase N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Survival protein SurE-like phosphatase/nucleotidase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Release factor glutamine methyltransferase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Shikimate dehydrogenase substrate binding N-terminal
Thiolase-like protein type 1 additional C-terminal
Peptide methionine sulphoxide reductase MsrA
Signal transduction histidine kinase dimerisation/phosphoacceptor
Penicillin-binding protein transpeptidase
Peptidase S9 prolyl oligopeptidase catalytic
Prepilin type IV endopeptidase peptidase
Magnesium chelatase subunit H N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Heat-inducible transcription repressor HrcA C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
O-(3'-phospho-DNA)-tyrosine intermediate
N-end rule aminoacyl transferase C-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
YpeB-like protein with protease inhibitory function
PhoD-like phosphatase metallophosphatase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Histidine-specific methyltransferase SAM-dependent
3-keto-disaccharide hydrolase domain-containing protein
NADH:ubiquinone oxidoreductase 30kDa subunit
Permuted papain-like amidase YaeF/Yiix C92 family enzyme
RNA binding; important for wobble base 34 recognition
Peptide methionine sulfoxide reductase MsrA
Phosphoadenosine phosphosulphate reductase
PHA accumulation regulator DNA-binding N-terminal
Photosynthetic reaction centre H subunit N-terminal
Heme-copper oxidase subunit III family profile
Sodium/calcium exchanger membrane region
Endoribonuclease L-PSP/chorismate mutase-like
O-(5'-phospho-DNA)-tyrosine intermediate
NADH:flavin oxidoreductase/NADH oxidase N-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Carbohydrate binding protein with CBM9 domain
Alanyl-transfer RNA synthetases family profile
Nucleophile; cysteine thiosulfonate intermediate
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
RND efflux pump membrane fusion protein barrel-sandwich
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Translation elongation factor P/YeiP central
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Saccharopine dehydrogenase-like C-terminal
Essential for prephenate dehydratase activity
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Large ribosomal subunit protein uL15/eL18
DNA replication/recombination mediator RecO N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Chromosomal replication initiator DnaA C-terminal
Cysteine sulfenic acid (-SOH) intermediate
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Manganese/iron superoxide dismutase C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Signal recognition particle SRP54 helical bundle
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Small ribosomal subunit protein uS4 N-terminal
Glycoside hydrolase family 42 N-terminal
Electron transfer via tryptophanyl radical
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Methionyl-tRNA synthetase anticodon-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Important for interaction with partner proteins
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Tetrahydrodipicolinate-N-succinyltransferase chain A
Required for zinc-mediated homotetramerization and catalytic activity
Type II secretion system protein TadB-like N-terminal
Prokaryotic-type class I peptide chain release factors
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Alpha-glycerophosphate oxidase C-terminal
Manganese/iron superoxide dismutase N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Polymerase/histidinol phosphatase N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Exonuclease VII large subunit C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Biopterin-dependent aromatic amino acid hydroxylase family profile
Sodium symporter small subunit predicted
CDP-alcohol phosphatidyltransferase C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Alpha-L-glutamate ligase-related protein ATP-grasp
Cobaltochelatase subunit CobS N-terminal
Putative auto-transporter adhesin head GIN
Chromosomal replication initiator protein DnaA
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Outer membrane beta-barrel porin/alpha-amylase
Terminase large subunit gp17-like C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Carbamoyl-phosphate synthase small subunit N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Pseudouridine synthase I TruA alpha/beta
S-adenosylmethionine-dependent methyltransferase
Glycosyl transferase family 3 N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
DNA mismatch repair proteins mutS family
NAD(P) transhydrogenase alpha subunit C-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Organic solvent tolerance-like N-terminal
Outer membrane protein beta-barrel domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Pyruvate phosphate dikinase AMP/ATP-binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glucose-methanol-choline oxidoreductase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
SUF system FeS cluster assembly SufBD N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA-directed DNA polymerase family A palm
Outer membrane protein assembly factor BamD
Reversibly protonated during proton transport
Poly-beta-hydroxybutyrate polymerase N-terminal
Resolvase/invertase-type recombinase catalytic
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Bacterial type II secretion system protein E