Probable transposase IS891/IS1136/IS1341
Major facilitator superfamily (MFS) profile
Glycosyl transferase family 3 N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Aminoacyl-transfer RNA synthetases class-II family profile
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Nicotinate phosphoribosyltransferase C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Tryptophan synthase beta chain-like PALP
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Dinitrogenase iron-molybdenum cofactor biosynthesis
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Aconitase A/isopropylmalate dehydratase small subunit swivel
Mandelate racemase/muconate lactonizing enzyme C-terminal
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
Aspartate/homoserine dehydrogenase NAD-binding
Glycine cleavage T-protein C-terminal barrel
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Bacterial type II secretion system protein E
Peptidase M1 membrane alanine aminopeptidase
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Phosphatidic acid phosphatase type 2/haloperoxidase
Molybdopterin cofactor biosynthesis C (MoaC)
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Phosphoribosylformylglycinamidine synthase linker
S-adenosyl-L-homocysteine hydrolase NAD binding
Electron transfer via tryptophanyl radical
Methionyl-tRNA synthetase anticodon-binding
DNA-directed RNA polymerase RBP11-like dimerisation
CRISPR-associated protein Cas6 C-terminal
Cytochrome c-552/DMSO reductase-like haem-binding
Cysteine sulfenic acid (-SOH) intermediate
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
CobB/CobQ-like glutamine amidotransferase
Inosine/uridine-preferring nucleoside hydrolase
RNA polymerase subunit H/Rpb5 C-terminal
Cytochrome oxidase subunit II copper A binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glycoside hydrolase family 57 N-terminal
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
NADH:ubiquinone oxidoreductase-like 20kDa subunit
DNA-directed RNA polymerase subunit 2 hybrid-binding
Peptidase S9 prolyl oligopeptidase catalytic
Glycoside hydrolase family 31 N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
tRNA nucleotidyltransferase substrate binding
Transcription regulator AsnC/Lrp ligand binding
Removed in mature form; by autocatalysis
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Cytochrome b/b6 N-terminal region profile
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Glycosyltransferase subfamily 4-like N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Small ribosomal subunit protein uS4 N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Large ribosomal subunit protein uL15/eL18
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Large ribosomal subunit protein uL2 C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
RNA 3'-terminal phosphate cyclase insert
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
D-galactarate/Altronate dehydratase C-terminal
Shikimate dehydrogenase substrate binding N-terminal
Iron dependent repressor metal binding and dimerisation
Serine/threonine specific protein phosphatases
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Spo11/DNA topoisomerase VI subunit A N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Nitrite/Sulfite reductase ferredoxin-like
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Bacterial bifunctional deaminase-reductase C-terminal
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Alanyl-transfer RNA synthetases family profile
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Phosphoadenosine phosphosulphate reductase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Anthranilate synthase component I N-terminal
ATPsynthase alpha/beta subunit N-terminal extension
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Large ribosomal subunit protein uL6 alpha-beta
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
SAM-dependent methyltransferase TRM5/TYW2-type
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Glycosyl transferase family 28 C-terminal
Increases nucleophilicity of active site Cys
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Peptide methionine sulphoxide reductase MsrA
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Translation elongation factor IF5A C-terminal
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Important for guanine/8-oxoguanine distinction
Myo-inositol-1-phosphate synthase GAPDH-like
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Small ribosomal subunit protein uS15 N-terminal
Heme-copper oxidase subunit III family profile
Transcription factor NikR nickel binding C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Polymerase/histidinol phosphatase N-terminal
Cation-transporting P-type ATPase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Schiff-base intermediate with D-ribose 5-phosphate
Sugar fermentation stimulation protein C-terminal
Plays an important role in substrate specificity
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Sodium/calcium exchanger membrane region