Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Inosine monophosphate cyclohydrolase-like
Meso-diaminopimelate D-dehydrogenase C-terminal
5-glutamyl coenzyme A thioester intermediate
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Anthranilate synthase component I N-terminal
Bacterial repeat domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Polymerase/histidinol phosphatase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Cell envelope-related transcriptional attenuator
Resolvase/invertase-type recombinase catalytic
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Sodium/calcium exchanger membrane region
Translation elongation factor P/YeiP central
Important for autoinhibition of adenylyltransferase activity
Major facilitator superfamily (MFS) profile
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Pyruvate phosphate dikinase AMP/ATP-binding
AB hydrolase-1 domain-containing protein
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Gram-positive cocci surface proteins LPxTG
Lacto-N-biose phosphorylase-like N-terminal TIM barrel
PrcB C-terminal domain-containing protein
Penicillin-binding protein transpeptidase
Prepilin type IV endopeptidase peptidase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
DNA-directed DNA polymerase family A palm
TRAP C4-dicarboxylate transport system permease DctM subunit
Transposase IS116/IS110/IS902 C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Membrane insertase YidC/Oxa/ALB C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Polysaccharide biosynthesis protein C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Phosphoribosylformylglycinamidine synthase linker
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Prokaryotic-type class I peptide chain release factors
Saccharopine dehydrogenase-like C-terminal
ABC transporter substrate-binding protein PnrA-like
Aminoacyl-transfer RNA synthetases class-II family profile
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
ABC-type uncharacterised transport system
Schiff-base intermediate with substrate; via pyruvic acid
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Plays an important role in substrate specificity
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 4
Stage III sporulation protein AA AAA+ ATPase
Pyrimidine nucleoside phosphorylase C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Shikimate dehydrogenase substrate binding N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
S-adenosylmethionine-dependent methyltransferase
Chromosomal replication initiator DnaA C-terminal
NIF system FeS cluster assembly NifU N-terminal
DNA mismatch repair proteins mutS family
Pesticidal crystal protein Cry22Aa Ig-like domain-containing protein
tRNA pseudouridylate synthase B C-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Polysaccharide biosynthesis protein CapD-like
Glycosyltransferase subfamily 4-like N-terminal
1-phosphatidylinositol phosphodiesterase
Phosphatidylinositol-specific phospholipase C X
Diacylglycerol glucosyltransferase N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Glucosamine/galactosamine-6-phosphate isomerase
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Membrane fusion protein biotin-lipoyl like
Heat-inducible transcription repressor HrcA C-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Probable transposase IS891/IS1136/IS1341
Helix-turn-helix conjugative transposon-like
CobB/CobQ-like glutamine amidotransferase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Endo-alpha-N-acetylgalactosaminidase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glycoside hydrolase family 42 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Important for beta-aspartyl-AMP intermediate formation
Restriction endonuclease AspBHI N-terminal
2,4-diaminopentanoate dehydrogenase C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Could play a key role in the communication between the regulatory and the substrate sites
Sporulation stage II protein D amidase enhancer LytB N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Large ribosomal subunit protein uL15/eL18
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Pyruvate/ketoisovalerate oxidoreductase catalytic
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Pseudouridine synthase I TruA alpha/beta
Essential for prephenate dehydratase activity
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Alanyl-transfer RNA synthetases family profile
Lysidine-tRNA(Ile) synthetase C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Interaction with polymerase core subunit RpoC
RNA 2-O ribose methyltransferase substrate binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Bacterial type II secretion system protein E
Large ribosomal subunit protein bL9 C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Tryptophan synthase beta chain-like PALP
Phosphotransferase system enzyme I N-terminal
Proton acceptor; for glutaminase activity
Reversibly protonated during proton transport
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Threonine/serine exporter-like N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Flavodoxin-like domain-containing protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
N6 adenine-specific DNA methyltransferase N-terminal
Choloylglycine hydrolase/NAAA C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Aminoacyl-tRNA synthetase class I anticodon-binding
HicB-like antitoxin of toxin-antitoxin system
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Thiamin pyrophosphokinase thiamin-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Sporulation initiation factor Spo0A C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal