Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glycine cleavage T-protein C-terminal barrel
Glycosyl hydrolase family 95 N-terminal domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
TonB-dependent receptor-like beta-barrel
Lipocalin-like domain-containing protein
Penicillin-binding protein transpeptidase
Glycosyltransferase subfamily 4-like N-terminal
Secretion system C-terminal sorting domain-containing protein
Activator of Hsp90 ATPase homologue 1-like C-terminal
Styrene monooxygenase StyA putative substrate binding
RNA polymerase sigma factor 70 region 4 type 2
RND efflux pump membrane fusion protein barrel-sandwich
Moybdenum cofactor oxidoreductase dimerisation
Outer membrane protein beta-barrel domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Resolvase/invertase-type recombinase catalytic
Gfo/Idh/MocA-like oxidoreductase N-terminal
Major facilitator superfamily (MFS) profile
Polymerase/histidinol phosphatase N-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Carboxypeptidase-like regulatory domain-containing protein
Putative auto-transporter adhesin head GIN
Ribonucleotide reductase large subunit C-terminal
Important for interaction with partner proteins
Gfo/Idh/MocA-like oxidoreductase C-terminal
Cationic amino acid transporter C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
NADH:ubiquinone oxidoreductase 30kDa subunit
DNA topoisomerase I catalytic core eukaryotic-type
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
ATP synthase F1 complex delta/epsilon subunit N-terminal
Sodium/calcium exchanger membrane region
Glutathionylspermidine synthase pre-ATP-grasp-like
Bacterial transcription activator effector binding
Signal transduction histidine kinase internal region
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Glucosamine/galactosamine-6-phosphate isomerase
Sialate O-acetylesterase domain-containing protein
Peptide methionine sulphoxide reductase MsrA
tRNA1(Val) (adenine(37)-N6)-methyltransferase
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Biopterin-dependent aromatic amino acid hydroxylase family profile
Phosphatidic acid phosphatase type 2/haloperoxidase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Positions MEP for the nucleophilic attack
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Butirosin biosynthesis protein H N-terminal
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Pectate lyase superfamily protein domain-containing protein
Surface glycan-binding protein B xyloglucan binding
Plays an important role in substrate specificity
DNA mismatch repair proteins mutS family
Glycoside hydrolase 123 C-terminal domain-containing protein
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Quercetin 2,3-dioxygenase C-terminal cupin
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Transposase IS116/IS110/IS902 C-terminal
P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
Bacterial bifunctional deaminase-reductase C-terminal
Type I restriction enzyme R protein N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Large ribosomal subunit protein uL2 C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Two component regulator propeller domain protein
Glycoside hydrolase family 5 domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Polysaccharide biosynthesis protein C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Membrane fusion protein biotin-lipoyl like
Cell division protein FtsQ/DivIB C-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Gamma-glutamylcyclotransferase AIG2-like
Inosine/uridine-preferring nucleoside hydrolase
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
3-keto-disaccharide hydrolase domain-containing protein
Heme-copper oxidase subunit III family profile
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein
Pyruvate phosphate dikinase AMP/ATP-binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Right handed beta helix domain-containing protein
NIF system FeS cluster assembly NifU C-terminal
Acetylserotonin O-methyltransferase dimerisation
Endoribonuclease L-PSP/chorismate mutase-like
Cysteine sulfenic acid (-SOH) intermediate
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Polysaccharide chain length determinant N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Peptidase M1 membrane alanine aminopeptidase
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Inner membrane protein YgaP-like transmembrane
Putative beta-lactamase-inhibitor-like PepSY-like
Putative beta-lactamase-inhibitor-like PepSY-like domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
Polysaccharide biosynthesis protein CapD-like
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
O-(5'-phospho-DNA)-tyrosine intermediate
Transcription elongation factor GreA/GreB C-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein
Pseudouridine synthase I TruA alpha/beta
Electron transfer via tryptophanyl radical
Could be important to modulate the pK values of the two catalytic cysteine residues
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
4'-phosphopantetheinyl transferase N-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Glycosyl transferase family 28 C-terminal
Type I restriction modification DNA specificity
Terminase large subunit-like endonuclease
Ribose-phosphate pyrophosphokinase N-terminal
Trigger factor ribosome-binding bacterial
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Translation elongation factor EFTs/EF1B dimerisation
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Antitoxin Xre/MbcA/ParS-like toxin-binding
SusD/RagB family nutrient-binding outer membrane lipoprotein
Fibronectin type-III domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Thiamin pyrophosphokinase thiamin-binding
Beta-xylosidase C-terminal Concanavalin A-like
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Shikimate dehydrogenase substrate binding N-terminal
Serine aminopeptidase S33 domain-containing protein
6-phosphogluconate dehydrogenase C-terminal
Schiff-base intermediate with acetaldehyde
Glycosyl-hydrolase 97 C-terminal oligomerisation
Putative adhesin domain-containing protein
Anthranilate synthase component I N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Gliding motility-associated C-terminal domain-containing protein
Neutral/alkaline non-lysosomal ceramidase N-terminal domain-containing protein
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Heparinase II N-terminal domain-containing protein
S-adenosyl-L-homocysteine hydrolase NAD binding
Mannose-6-phosphate isomerase type II C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Membrane insertase YidC/Oxa/ALB C-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Neutral/alkaline non-lysosomal ceramidase N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Murein L,D-transpeptidase catalytic domain family protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Carbamoyl-phosphate synthase small subunit N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Type III restriction enzyme C-terminal endonuclease
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
BclB C-terminal domain-containing protein
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Glycerophosphoryl diester phosphodiesterase
Alpha-glycerophosphate oxidase C-terminal
ATP-grasp fold succinyl-CoA synthetase-type
Large ribosomal subunit protein uL15/eL18
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Membrane protein involved in aromatic hydrocarbon degradation
Pyridoxamine 5'-phosphate oxidase putative
CD-NTase-associated protein 12/Pycsar effector protein TIR
Polysaccharide pyruvyl transferase domain-containing protein
Abortive infection protein-like C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Peptidase M43 pregnancy-associated plasma-A
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Endo-alpha-N-acetylgalactosaminidase domain-containing protein
DNA-directed DNA polymerase family A palm
Survival protein SurE-like phosphatase/nucleotidase
Alginate export domain-containing protein
RNA 2-O ribose methyltransferase substrate binding
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Nitrite/Sulfite reductase ferredoxin-like
Urease accessory protein UreH-like transmembrane
HicB-like antitoxin of toxin-antitoxin system
Type IX secretion system protein PorV domain-containing protein
Type 1 periplasmic binding fold superfamily protein
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Ysc84 actin-binding domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Alanyl-transfer RNA synthetases family profile
Beta-hexosaminidase bacterial type N-terminal
Translation elongation factor P/YeiP central
UDP N-acetylglucosamine O-acyltransferase C-terminal
Integral membrane protein YccS N-terminal
Putative auto-transporter adhesin head GIN domain-containing protein
Glycoside hydrolase family 13 N-terminal
Nickel transport complex, NikM subunit, transmembrane
Prokaryotic-type class I peptide chain release factors
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Heavy metal-binding domain-containing protein
Gliding motility protein SprA N-terminal
Transcription elongation factor GreA/GreB N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
ATP-dependent exodnase (Exonuclease V) alpha subunit-helicase superfamily I member
General stress protein FMN-binding split barrel
TerB family tellurite resistance protein
PsbP C-terminal domain-containing protein
Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP
Microcin J25-processing protein McjB C-terminal
Chitobiase/beta-hexosaminidases N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Phosphatidate phosphatase APP1 catalytic
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Large ribosomal subunit protein uL6 alpha-beta
Aminoacyl-tRNA synthetase class I anticodon-binding
Small ribosomal subunit protein uS4 N-terminal
Leucine-binding protein domain-containing protein
Saccharopine dehydrogenase-like C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Thymidylate synthase/dCMP hydroxymethylase
Glycosyl transferase family 3 N-terminal
Carbohydrate-binding domain-containing protein
Histidine-specific methyltransferase SAM-dependent
Lysidine-tRNA(Ile) synthetase C-terminal
DNA replication/recombination mediator RecO N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Ribosomal RNA small subunit methyltransferase E methyltransferase
Proton acceptor; for glutaminase activity
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Bacterial DNA polymerase III alpha subunit NTPase
DNA polymerase helix-hairpin-helix motif
Leucine-rich repeat-containing N-terminal plant-type
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Menaquinone biosynthesis protein MenD middle
Type 2A encapsulin shell protein SrpI-like
ABC-type uncharacterised transport system
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
S-adenosylmethionine-dependent methyltransferase
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Glycosyltransferase family 28 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal