Enoyl-[acyl-carrier-protein] reductase [NADH]
Plays an important role in discriminating NADH against NADPH
Inosine/uridine-preferring nucleoside hydrolase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Major facilitator superfamily (MFS) profile
Exopolysaccharide production protein YjbE
Phosphoribosylaminoimidazole-succinocarboxamide synthase
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Phosphocysteine intermediate; for EIIB activity
Crossover junction endodeoxyribonuclease RuvC
Plays an important role in substrate specificity
Pyrimidine/purine nucleoside phosphorylase
Glucan biosynthesis periplasmic MdoG C-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Chromosome partition protein MukF C-terminal
Chromosome partition protein MukF middle
Chromosome partition protein MukF winged-helix
D-galactose/methyl-galactoside binding periplasmic protein MglB
RNA polymerase sigma factor 70 region 4 type 2
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Phosphoethanolamine transferase N-terminal
Flagellar motor switch protein FliN-like C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
6-phosphogluconate dehydrogenase C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
4-hydroxy-tetrahydrodipicolinate reductase
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Reversibly protonated during proton transport
Lysidine-tRNA(Ile) synthetase C-terminal
Flagellar basal body rod protein N-terminal
Interaction with polymerase core subunit RpoC
ABC-type glycine betaine transport system substrate-binding
Flagella basal body P-ring formation protein FlgA
Ion-translocating oxidoreductase complex subunit E
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Bacterial type II secretion system protein E
N-acetylmuramic acid 6-phosphate etherase
Holliday junction branch migration complex subunit RuvA
YbaK/aminoacyl-tRNA synthetase-associated
Tellurite resistance methyltransferase TehB-like
Tryptophan synthase beta chain-like PALP
FAD-dependent oxidoreductase 2 FAD binding
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
2-dehydro-3-deoxyphosphooctonate aldolase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Solute-binding protein family 3/N-terminal
ATP-dependent Clp protease adapter protein ClpS
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
O-(3'-phospho-DNA)-tyrosine intermediate
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
RNA methyltransferase SpoU/TrmH type C-terminal
Penicillin-binding protein transpeptidase
Resolvase/invertase-type recombinase catalytic
Anthranilate synthase component I N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Phosphatidic acid phosphatase type 2/haloperoxidase
Alanyl-transfer RNA synthetases family profile
RNA binding; important for wobble base 34 recognition
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
Flagellar hook-basal body complex protein FliE
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Schiff-base intermediate with acetaldehyde
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Probable septum site-determining protein MinC
Flagellar assembly protein FliH/Type III secretion system HrpE
Glutathione-regulated potassium-efflux system protein KefB
Carboxy-S-adenosyl-L-methionine synthase
Cysteine sulfenic acid (-SOH) intermediate
Capsule biosynthesis GfcC-like C-terminal
Capsule biosynthesis GfcC-like N-terminal
Prokaryotic-type class I peptide chain release factors
Large-conductance mechanosensitive channel
Outer membrane protein assembly factor BamE
Transcriptional regulator SgrR N-terminal HTH
Shikimate dehydrogenase substrate binding N-terminal
3-deoxy-manno-octulosonate cytidylyltransferase
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Ionotropic glutamate receptor C-terminal
Flagellar basal-body/hook protein C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Appears to be important in orienting the phosphate for catalysis
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Protein-L-isoaspartate O-methyltransferase
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine 5'-phosphosulfate reductase
Glycosyltransferase subfamily 4-like N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Ribosomal RNA large subunit methyltransferase H
High frequency lysogenization protein HflD homolog
DNA polymerase III delta subunit C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Outer membrane protein assembly factor BamA
Ion-translocating oxidoreductase complex subunit D
Aspartate/homoserine dehydrogenase NAD-binding
Ion-translocating oxidoreductase complex subunit C
Ribosomal RNA large subunit methyltransferase G
3-methyl-2-oxobutanoate hydroxymethyltransferase
Arginine decarboxylase C-terminal helical
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Sodium/calcium exchanger membrane region
Gly-cisPro motif, important for rejection of L-amino acids
Disulphide bond isomerase DsbC/G N-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Carbamoyl-phosphate synthase small subunit N-terminal
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
Proline utilization A proline dehydrogenase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Cytochrome c-type biogenesis protein CcmE
Helical; Signal-anchor for type II membrane protein
HNH/Endo VII superfamily nuclease toxins
Glutamate-1-semialdehyde 2,1-aminomutase
RNA 2-O ribose methyltransferase substrate binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Chromosomal replication initiator protein DnaA
Positions MEP for the nucleophilic attack
UDP-3-O-acyl-N-acetylglucosamine deacetylase
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase
Lipoprotein SmpA/OmlA domain-containing protein
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Peptide methionine sulfoxide reductase MsrA
Flagellar motor switch protein FliN N-terminal
YdgH/BhsA/McbA-like domain-containing protein
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Xanthine-guanine phosphoribosyltransferase
DNA polymerase III subunit delta C-terminal
Outer membrane protein assembly factor BamD
TonB-dependent receptor-like beta-barrel
Membrane-bound lytic murein transglycosylase F
Involved in allosteric activation by GTP
Succinate--CoA ligase [ADP-forming] subunit beta
Nucleoside-specific channel-forming protein Tsx
Bifunctional purine biosynthesis protein PurH
Involved in Mg(2+) ion dislocation from EF-Tu
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
SUF system FeS cluster assembly SufBD N-terminal
Polyribonucleotide nucleotidyltransferase
Choloylglycine hydrolase/NAAA C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
O-(5'-phospho-DNA)-tyrosine intermediate
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Thiol:disulfide interchange protein DsbD
Type II secretion system protein GspG C-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Ribosomal RNA large subunit methyltransferase M
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Probable Sec-independent protein translocase protein TatE
4-hydroxythreonine-4-phosphate dehydrogenase
Potassium-transporting ATPase ATP-binding subunit
N-succinylglutamate 5-semialdehyde dehydrogenase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Hypersensitivity response secretion-like HrpJ
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Cytochrome c-type biogenesis protein CcmF C-terminal
Potassium-transporting ATPase KdpC subunit
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Ribosomal RNA large subunit methyltransferase I
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Ion-translocating oxidoreductase complex subunit A
ATP-dependent protease ATPase subunit HslU
5-glutamyl coenzyme A thioester intermediate
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Moves into active site upon enzyme activation, plays a role in electron transfer
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Type II secretion system protein GspC N-terminal
Polysaccharide chain length determinant N-terminal
4'-phosphopantetheinyl transferase N-terminal
3-isopropylmalate dehydratase small subunit
Outer-membrane lipoprotein carrier protein
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
DNA-directed DNA polymerase family A palm
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase
tRNA1(Val) (adenine(37)-N6)-methyltransferase
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Could play a key role in the communication between the regulatory and the substrate sites
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Pyridoxine/pyridoxamine 5'-phosphate oxidase
Oxygen-dependent coproporphyrinogen-III oxidase
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase
Bacteriophage T7 Gp4 DNA primase/helicase N-terminal
DnaJ homologue subfamily C member 28 conserved
Cytochrome C biogenesis protein transmembrane
DNA-directed RNA polymerase subunit beta
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
p-hydroxybenzoic acid efflux pump subunit AaeA
Ribosomal RNA small subunit methyltransferase F
Iron-sulfur cluster insertion protein ErpA
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Important for beta-aspartyl-AMP intermediate formation
3,4-dihydroxy-2-butanone 4-phosphate synthase
3-phosphoshikimate 1-carboxyvinyltransferase
Leucyl/phenylalanyl-tRNA--protein transferase
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical
Mechanosensitive ion channel inner membrane
Phosphotransferase system enzyme I N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Elongation factor P--(R)-beta-lysine ligase
Heme-copper oxidase subunit III family profile
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
Lysozyme inhibitor LprI N-terminal domain-containing protein
DNA protection during starvation protein
Holliday junction branch migration complex subunit RuvB
Penicillin-binding protein activator LpoB
YcgL domain-containing protein ETA_15380
Cytochrome b561 bacterial/Ni-hydrogenase
Peptidase S8/S53 domain-containing protein
Type I restriction modification DNA specificity
AB hydrolase-1 domain-containing protein
Ribosomal RNA large subunit methyltransferase E
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Transcription antitermination protein NusB
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Required for dimer formation and molybdate binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Ribosomal RNA small subunit methyltransferase B
Integral membrane protein YccS N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Membrane fusion protein biotin-lipoyl like
Type IV secretion system coupling protein TraD DNA-binding
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Prepilin type IV endopeptidase peptidase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Potassium-transporting ATPase potassium-binding subunit
Sulfite reductase [NADPH] hemoprotein beta-component
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Interaction with tRNA; Important for base-flipping
Pseudouridine synthase I TruA alpha/beta
CagE TrbE VirB component of type IV transporter system central
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Deoxyuridine 5'-triphosphate nucleotidohydrolase
Electron transfer via tryptophanyl radical
ABC-type transport auxiliary lipoprotein component
Phenylalanine--tRNA ligase alpha subunit
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Ribosomal RNA large subunit methyltransferase K/L
Outer-membrane lipoprotein Wza C-terminal
tRNA/tmRNA (uracil-C(5))-methyltransferase
Ion-translocating oxidoreductase complex subunit G
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Copper resistance protein ScsC N-terminal
Cell division topological specificity factor
Pyridine nucleotide-disulphide oxidoreductase dimerisation
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Cyclic pyranopterin monophosphate synthase
Flagellar hook-length control protein-like C-terminal
Type VI secretion system IcmF C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Probable transcriptional regulatory protein ETA_14870
Formate-dependent phosphoribosylglycinamide formyltransferase
Dual-specificity RNA methyltransferase RlmN
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD
Essential for prephenate dehydratase activity
Bifunctional polymyxin resistance protein ArnA
Proton acceptor; for decarboxylase activity
Proton donor; for decarboxylase activity
Proton donor; for formyltransferase activity
Important for interaction with partner proteins
Essential for degradation by Lon protease
tRNA N6-adenosine threonylcarbamoyltransferase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Bacterial collagen-like protein middle domain-containing protein
Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-255)
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-108)
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Acyltransferase MbtK/IucB-like conserved
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Prepilin peptidase dependent protein C-like C-terminal
Methylguanine DNA methyltransferase ribonuclease-like
Interacts with tRNA; defines subfamily-specific binding signature
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Aspartate carbamoyltransferase regulatory chain
Peptide methionine sulfoxide reductase MsrB
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Type VI secretion system-associated protein
DNA-directed RNA polymerase subunit beta'
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Penicillin-binding protein activator LpoA
Ribosomal RNA small subunit methyltransferase G
Small ribosomal subunit biogenesis GTPase RsgA
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Type II secretion system protein GspI C-terminal
Protein-methionine-sulfoxide reductase catalytic subunit MsrP
Glycosyl transferase family 3 N-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
N6 adenine-specific DNA methyltransferase N-terminal
4-hydroxy-tetrahydrodipicolinate synthase
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Soluble pyridine nucleotide transhydrogenase
Ubiquinone biosynthesis O-methyltransferase
Alpha-glycerophosphate oxidase C-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Type VII secretion system protein EssD-like
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Pyruvate dehydrogenase E1 component middle
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Terminase large subunit gp17-like C-terminal
Cation-transporting P-type ATPase N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Polypeptide-transport-associated ShlB-type
Type III restriction/modification enzyme methylation subunit
Ribosomal RNA small subunit methyltransferase A
Acyl-CoA dehydrogenase C-terminal bacterial-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Ribosomal RNA small subunit methyltransferase H
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Purine nucleoside phosphorylase DeoD-type
Thymidylate synthase/dCMP hydroxymethylase
Release factor glutamine methyltransferase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Ion-translocating oxidoreductase complex subunit B
Pyruvate phosphate dikinase AMP/ATP-binding
Putative phosphoenolpyruvate synthase regulatory protein
Glucose-methanol-choline oxidoreductase C-terminal
Polymerase/histidinol phosphatase N-terminal
Phosphoribosylformylglycinamidine cyclo-ligase
DNA-directed RNA polymerase subunit omega
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Fimbrial-type adhesion domain-containing protein
Required for zinc-mediated homotetramerization and catalytic activity