Electron transfer flavoprotein alpha/beta-subunit N-terminal
Tryptophan synthase beta chain-like PALP
Cysteine sulfenic acid (-SOH) intermediate
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
ABC transporter substrate-binding protein
Major facilitator superfamily (MFS) profile
Nitrite/Sulfite reductase ferredoxin-like
Invasion associated locus B family protein
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
TonB-dependent receptor-like beta-barrel
Outer membrane protein beta-barrel domain-containing protein
AraC-type arabinose-binding/dimerisation
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Glycosyltransferase subfamily 4-like N-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
TRAP C4-dicarboxylate transport system permease DctM subunit
Pyridoxamine 5'-phosphate oxidase putative
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
RNA polymerase sigma factor 70 region 4 type 2
N-end rule aminoacyl transferase C-terminal
6-phosphogluconate dehydrogenase C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Transcriptional regulator AbiEi antitoxin N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Gp5/Type VI secretion system Vgr protein OB-fold
NIF system FeS cluster assembly NifU N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Phosphoadenosine phosphosulphate reductase
RNA binding; important for wobble base 34 recognition
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Aromatic amino acid beta-eliminating lyase/threonine aldolase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Peptidase S9 prolyl oligopeptidase catalytic
Phosphatidic acid phosphatase type 2/haloperoxidase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Protocatechuate 3,4-dioxygenase beta subunit N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Bacterial bifunctional deaminase-reductase C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Tetrahydrodipicolinate-N-succinyltransferase chain A
Tripartite tricarboxylate transporter substrate binding protein
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Flagellar Assembly Protein A N-terminal region
Gamma-glutamylcyclotransferase AIG2-like
6-phosphogluconate dehydrogenase NADP-binding
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Solute-binding protein family 3/N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
DNA mismatch repair proteins mutS family
Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
BAAT/Acyl-CoA thioester hydrolase C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Reversibly protonated during proton transport
Membrane fusion protein biotin-lipoyl like
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Solute-binding protein family 3/N-terminal domain-containing protein
O-(5'-phospho-DNA)-tyrosine intermediate
Pyruvate phosphate dikinase AMP/ATP-binding
Carboxypeptidase regulatory-like domain-containing protein
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Large ribosomal subunit protein uL2 C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Sodium/calcium exchanger membrane region
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Type VI secretion system IcmF C-terminal
Positions MEP for the nucleophilic attack
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Required for zinc-mediated homotetramerization and catalytic activity
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Adaptive response protein AidB N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Chromosomal replication initiator DnaA C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Heme-copper oxidase subunit III family profile
RND efflux pump membrane fusion protein barrel-sandwich
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Flagella basal body P-ring formation protein FlgA
Phosphotransferase system enzyme I N-terminal
N,N-dimethylformamidase beta subunit-like C-terminal
Interaction with polymerase core subunit RpoC
ABC-type transport auxiliary lipoprotein component
Large ribosomal subunit protein bL9 C-terminal
Prokaryotic-type class I peptide chain release factors
Flagellar hook-length control protein-like C-terminal
Outer-membrane lipoprotein carrier protein
Outer membrane protein assembly factor BamB
Leucine-binding protein domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Moybdenum cofactor oxidoreductase dimerisation
Glucan biosynthesis periplasmic MdoG C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Interacts with tRNA; defines subfamily-specific binding signature
Mannose-6-phosphate isomerase type II C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Bacterial type II secretion system protein E
Peptide methionine sulphoxide reductase MsrA
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Plays an important role in substrate specificity
Toxin co-regulated pilus biosynthesis protein Q C-terminal
Toxin co-regulated pilus biosynthesis protein Q C-terminal domain-containing protein
Transposase IS204/IS1001/IS1096/IS1165 DDE
Polymerase/histidinol phosphatase N-terminal
D-galactarate/Altronate dehydratase C-terminal
Resolvase/invertase-type recombinase catalytic
Dipeptidylpeptidase IV N-terminal domain-containing protein
PHA accumulation regulator DNA-binding N-terminal
Bacteriophage tail tape measure C-terminal
Bacteriophage tail tape measure N-terminal
Glycine cleavage T-protein C-terminal barrel
Pyruvate dehydrogenase E1 component middle
Essential for prephenate dehydratase activity
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Ionotropic glutamate receptor C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Large ribosomal subunit protein uL15/eL18
Nucleophile; cysteine thiosulfonate intermediate
Moves into active site upon enzyme activation, plays a role in electron transfer
Penicillin-binding protein transpeptidase
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Proline utilization A proline dehydrogenase N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
DNA-directed DNA polymerase family A palm
UDP-glucose/GDP-mannose dehydrogenase C-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Chromosomal replication initiator protein DnaA
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Aspartate/homoserine dehydrogenase NAD-binding
Polysaccharide chain length determinant N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Translation elongation factor P/YeiP central
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Bacterial surface antigen (D15) domain-containing protein
Release factor glutamine methyltransferase N-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
Important for interaction with partner proteins
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Lipoprotein YgdI/YgdR-like SH3-like domain-containing protein
ATP synthase F1 complex delta/epsilon subunit N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
S-adenosyl-L-homocysteine hydrolase NAD binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
RNA 2-O ribose methyltransferase substrate binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Proton acceptor; for glutaminase activity
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Putative Flp pilus-assembly TadG-like N-terminal
AB hydrolase-1 domain-containing protein
Outer membrane protein assembly factor BamC
Integral membrane protein YccS N-terminal
Prepilin type IV endopeptidase peptidase
Flagellar motor switch protein FliN-like C-terminal
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Beta-lactamase-related domain-containing protein
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Survival protein SurE-like phosphatase/nucleotidase
Methylaspartate ammonia-lyase C-terminal
Methylaspartate ammonia-lyase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Disulphide bond isomerase DsbC/G N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Exonuclease VII large subunit C-terminal
Peptide methionine sulfoxide reductase MsrA
Lipoprotein SmpA/OmlA domain-containing protein
ABC-type transport auxiliary lipoprotein component domain-containing protein
Superoxide dismutase copper/zinc binding
Pseudouridine synthase I TruA alpha/beta
Glucosamine/galactosamine-6-phosphate isomerase
Activator of Hsp90 ATPase homologue 1-like C-terminal
HicB-like antitoxin of toxin-antitoxin system
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Glycosyl transferase family 3 N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Shikimate dehydrogenase substrate binding N-terminal
Alanyl-transfer RNA synthetases family profile
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Signal recognition particle SRP54 helical bundle
Cytochrome C biogenesis protein transmembrane
NADH:ubiquinone oxidoreductase 30kDa subunit
DNA replication/recombination mediator RecO N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Putative regulatory protein FmdB Zinc ribbon
O-(3'-phospho-DNA)-tyrosine intermediate
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Small ribosomal subunit protein uS4 N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Helix-hairpin-helix DNA-binding motif class 1
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glycine zipper 2TM domain-containing protein
Lysozyme inhibitor LprI N-terminal domain-containing protein
Twin-arginine translocation pathway signal
Autotransporter domain-containing protein
tRNA pseudouridylate synthase B C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Alpha-glycerophosphate oxidase C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Molybdopterin cofactor biosynthesis C (MoaC)
Guanylate kinase/L-type calcium channel beta subunit
Ribosomal RNA adenine methylase transferase N-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
NADH-rubredoxin oxidoreductase C-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
SsuA/THI5-like domain-containing protein
Cobalamin-independent methionine synthase MetE N-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Anthranilate synthase component I N-terminal
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Poly-beta-hydroxybutyrate polymerase N-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Ysc84 actin-binding domain-containing protein
Thymidylate synthase/dCMP hydroxymethylase
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central