ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Major facilitator superfamily (MFS) profile
Anthranilate synthase component I N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Pyridoxamine 5'-phosphate oxidase putative
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Outer membrane protein assembly factor BamB
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Glycoside-hydrolase family GH114 TIM-barrel
Glycoside-hydrolase family GH114 TIM-barrel domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Glucosamine/galactosamine-6-phosphate isomerase
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Sugar ABC transporter substrate-binding protein
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Polymerase/histidinol phosphatase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
O-(5'-phospho-DNA)-tyrosine intermediate
Cytochrome C biogenesis protein transmembrane
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Important for substrate specificity; cannot use PPi as phosphoryl donor
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Leucine-binding protein domain-containing protein
Glycosyl transferase family 3 N-terminal
Essential for prephenate dehydratase activity
DNA-directed DNA polymerase family A palm
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Mandelate racemase/muconate lactonizing enzyme C-terminal
ABC transporter substrate-binding protein PnrA-like
ABC transporter substrate-binding protein PnrA-like domain-containing protein
Heat-inducible transcription repressor HrcA C-terminal
Fibronectin type-III domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Ricin B lectin domain-containing protein
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Schiff-base intermediate with D-ribose 5-phosphate
DNA primase/polymerase bifunctional N-terminal
Tryptophan synthase beta chain-like PALP
S-adenosyl-L-homocysteine hydrolase NAD binding
Glycoside hydrolase family 42 N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Solute-binding protein family 3/N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Alanyl-transfer RNA synthetases family profile
Pectate lyase superfamily protein domain-containing protein
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Glycerophosphoryl diester phosphodiesterase membrane
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glycoside hydrolase family 3 N-terminal domain-containing protein
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
ATP synthase F1 complex delta/epsilon subunit N-terminal
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Putative exodeoxyribonuclease 8 PDDEXK-like
NIF system FeS cluster assembly NifU N-terminal
Glycoside hydrolase GH146 substrate-binding
Could play a key role in the communication between the regulatory and the substrate sites
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Aminoacyl-transfer RNA synthetases class-II family profile
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Threonine/serine exporter-like N-terminal
Threonine/serine exporter-like N-terminal domain-containing protein
Cytochrome b/b6 N-terminal region profile
Peptidase M1 membrane alanine aminopeptidase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
General stress protein FMN-binding split barrel
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Bacterial bifunctional deaminase-reductase C-terminal
Phenol hydroxylase C-terminal dimerisation
Cell envelope-related transcriptional attenuator
Phosphotransferase system enzyme I N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
ABC transporter substrate-binding protein
Translation elongation factor P/YeiP central
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Formamidopyrimidine-DNA glycosylase catalytic
Membrane insertase YidC/Oxa/ALB C-terminal
Gram-positive cocci surface proteins LPxTG domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Phosphatidic acid phosphatase type 2/haloperoxidase
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Ionotropic glutamate receptor C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Lipopolysaccharide assembly protein A domain-containing protein
Electron transfer via tryptophanyl radical
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Putative Flp pilus-assembly TadG-like N-terminal
Penicillin-binding protein transpeptidase
C-type lysozyme inhibitor domain-containing protein
N-acetylneuraminic acid synthase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Reversibly protonated during proton transport
Atrophied bacterial Ig domain-containing protein
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Shikimate dehydrogenase substrate binding N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Pyruvate dehydrogenase E1 component middle
CobB/CobQ-like glutamine amidotransferase
Prokaryotic-type class I peptide chain release factors
DNA topoisomerase I catalytic core eukaryotic-type
Type I restriction modification DNA specificity
Ribosomal RNA adenine methylase transferase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
RNA 2-O ribose methyltransferase substrate binding
Moybdenum cofactor oxidoreductase dimerisation
Interaction with polymerase core subunit RpoC
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Chromosomal replication initiator DnaA C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Cytochrome oxidase subunit II copper A binding
ABC-type glycine betaine transport system substrate-binding
ABC-type glycine betaine transport system substrate-binding domain-containing protein
Phosphomannose isomerase type I catalytic
DNA replication/recombination mediator RecO N-terminal
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Methionyl-tRNA synthetase anticodon-binding
Polysaccharide biosynthesis protein CapD-like
Mannose-6-phosphate isomerase type II C-terminal
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Sporulation transcription regulator WhiA N-terminal
Heme-copper oxidase subunit III family profile
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Ribose-phosphate pyrophosphokinase N-terminal
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Solute-binding protein family 3/N-terminal domain-containing protein
Signal recognition particle SRP54 helical bundle
Cytochrome b561 bacterial/Ni-hydrogenase
Phosphatidate phosphatase APP1 catalytic
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Peptide methionine sulphoxide reductase MsrA
Lantibiotic biosynthesis protein dehydration
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Small ribosomal subunit protein uS4 N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Bacterial Ig-like domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Schiff-base intermediate with substrate; via topaquinone
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
tRNA pseudouridylate synthase B C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Cation-transporting P-type ATPase N-terminal
Plays an important role in substrate specificity
Right handed beta helix domain-containing protein
Inosine/uridine-preferring nucleoside hydrolase
Putative regulatory protein FmdB Zinc ribbon
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Moves into active site upon enzyme activation, plays a role in electron transfer
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Peptidase M14 carboxypeptidase A domain-containing protein
BetI-type transcriptional repressor C-terminal
Bacterial type II secretion system protein E
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Pyrimidine nucleoside phosphorylase C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Cytochrome bc1 complex cytochrome c subunit
Restriction system protein Mrr-like N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Release factor glutamine methyltransferase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal