Saccharopine dehydrogenase-like C-terminal
Major facilitator superfamily (MFS) profile
RNA 2-O ribose methyltransferase substrate binding
Non-structural maintenance of chromosome element 4 C-terminal
Anaphase-promoting complex subunit 4-like WD40
U3 small nucleolar RNA-associated protein 13 C-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Peptidase M1 membrane alanine aminopeptidase
Translation elongation factor IF5A C-terminal
DNA-directed DNA polymerase family A palm
Small ribosomal subunit protein uS2 C-terminal
TATA box binding protein associated factor (TAF) histone-like fold
Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding
Peptidase S9 prolyl oligopeptidase catalytic
Cysteine persulfide intermediate; for sulfurtransferase activity
Glycyl thioester intermediate; for adenylyltransferase activity
GPI ethanolamine phosphate transferase 2 C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Nucleoporin Nup133/Nup155-like C-terminal
Nucleoporin Nup133/Nup155-like N-terminal
Phosphatidylglycerol/phosphatidylinositol transfer protein
Extracellular mutant protein 11 C-terminal
Exocyst complex subunit Sec15 C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
AMP-activated protein kinase glycogen-binding
Important for beta-aspartyl-AMP intermediate formation
Cation-transporting P-type ATPase N-terminal
Spindle pole body component 110 C-terminal
Histone-binding protein RBBP4 N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glycoside hydrolase family 31 N-terminal
tRNA-splicing endonuclease subunit Sen15
Cell wall protein YJL171C/Tos1 C-terminal
Cell wall protein YJL171C/Tos1 N-terminal
tRNA-splicing endonuclease subunit Sen54 N-terminal
DNA polymerase alpha subunit B N-terminal
DNA polymerase alpha/delta/epsilon subunit B
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
NIF system FeS cluster assembly NifU N-terminal
RNA polymerase II assembly factor Rtp1 C-terminal
Nucleophile; Schiff-base intermediate with DNA; for 5'-dRP lyase activity
TATA element modulatory factor 1 TATA binding
Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated
25S rRNA (uridine-N(3))-methyltransferase BMT5-like
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Inositol polyphosphate-related phosphatase
Glucosamine/galactosamine-6-phosphate isomerase
Spindle pole body-associated protein Vik1/Cik1 microtubule binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Phosphoadenosine phosphosulphate reductase
FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit
GATOR complex protein MIO zinc-ribbon like
Exosome complex component CSL4 C-terminal
Nuclear speckle splicing regulatory protein 1 N-terminal
Exocyst complex component EXOC2/Sec5 N-terminal
Large ribosomal subunit protein uL15/eL18
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
Translation initiation factor beta propellor-like
Ribosomal RNA-processing protein 7 C-terminal
Ribosomal RNA methyltransferase SPB1-like C-terminal
Vacuolar protein 14 C-terminal Fig4-binding
Large ribosomal subunit protein bL17m C-terminal fungi
Large ribosomal subunit protein uL18 C-terminal eukaryotes
ATP synthase F1 complex delta/epsilon subunit N-terminal
Vacuolar import/degradation Vid27 C-terminal
Ribosomal RNA-processing protein 12-like conserved
Elongation factor 1 beta central acidic region eukaryote
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1
Monopolin complex subunit Csm1/Pcs1 C-terminal
Transcription initiation factor IIA gamma subunit C-terminal
Transcription initiation factor IIA gamma subunit N-terminal
Telomere length regulation protein conserved
Endoplasmic reticulum vesicle transporter C-terminal
Endoplasmic reticulum vesicle transporter N-terminal
Superoxide dismutase copper/zinc binding
26S proteasome regulatory subunit RPN2 C-terminal
Large ribosomal subunit protein uL2 C-terminal
Transcription initiation factor TFIID subunit 12
GPI-GlcNAc transferase complex PIG-H component conserved
Proteasome activator complex subunit 4 C-terminal
DNA-directed RNA polymerase RBP11-like dimerisation
Pyridine nucleotide-disulphide oxidoreductase dimerisation
18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal
26S proteasome non-ATPase regulatory subunit RPN1 C-terminal
G protein-coupled receptor GPR1 C-terminal
Exocyst complex subunit Exo70 C-terminal
Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase N-terminal
Large ribosomal subunit protein uL10-like insertion
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Survival protein SurE-like phosphatase/nucleotidase
V-type proton ATPase subunit S1/VOA1 transmembrane
RNA polymerase III subunit RPC82-related helix-turn-helix
Eukaryotic glycogen debranching enzyme N-terminal
Glycogen debranching enzyme glucanotransferase
Chromosome segregation protein Spc25 C-terminal
DNA replication regulator Sld3 C-terminal
Cell division control protein 73 C-terminal
Autophagy-related protein 2 middle RBG module
Clathrin/coatomer adaptor adaptin-like N-terminal
Tryptophan synthase beta chain-like PALP
DNA mismatch repair proteins mutS family
Large ribosomal subunit protein uL4 C-terminal
Bicarbonate transporter-like transmembrane
CCR4-NOT transcription complex subunit 1
CCR4-NOT transcription complex subunit 1 CAF1-binding
CCR4-NOT transcription complex subunit 1 HEAT repeat
CCR4-NOT transcription complex subunit 1 HEAT repeat 1
CCR4-NOT transcription complex subunit 1 TTP binding
CCR4-Not complex component Not1 C-terminal
Serine/threonine specific protein phosphatases
tRNA(Met) cytidine acetyltransferase TmcA N-terminal
Large ribosomal subunit protein mL46 N-terminal
Nucleolar complex-associated protein 3 N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Anthranilate synthase component I N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Threonine/serine exporter-like N-terminal
Methionyl-tRNA synthetase N-terminal heteromerisation
Methionyl-tRNA synthetase anticodon-binding
Mitochondrial adapter protein MCP1 transmembrane
INO80 complex subunit B-like conserved region
Iron hydrogenase large subunit C-terminal
Spo11/DNA topoisomerase VI subunit A N-terminal
Abscisic acid G-protein coupled receptor-like
Gamma tubulin complex component C-terminal
Gamma tubulin complex component protein N-terminal
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
Ubiquitin carboxyl-terminal hydrolase family 1 cysteine active-site
Vacuolar protein sorting-associated protein 13 DH-like
Vacuolar protein sorting-associated protein 13 VPS13 adaptor binding
Vacuolar protein sorting-associated protein 13 extended chorein
Anaphase-promoting complex subunit 4 long
Activator of Hsp90 ATPase AHSA1-like N-terminal
Prokaryotic-type class I peptide chain release factors
Glycosyltransferase subfamily 4-like N-terminal
Restriction of telomere capping protein 4 C-terminal
DNA replication complex GINS protein SLD5 C-terminal
Vacuolar protein sorting-associated protein 8 central
Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term
Transcriptional repressor Tup1 N-terminal
Manganese/iron superoxide dismutase C-terminal
Large ribosomal subunit protein bL27m C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Glycosyl transferase family 3 N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Phosphatidylserine amidated glycine; alternate
Cysteine sulfenic acid (-SOH) intermediate
N-end rule aminoacyl transferase C-terminal
DNA-directed RNA polymerase subunit 2 hybrid-binding
Conserved oligomeric Golgi complex subunit 4
Ancestral coatomer element 1 Sec16/Sec31
CCR4-Not complex component Not N-terminal
Yeast cell wall synthesis Kre9/Knh1 C-terminal
Yeast cell wall synthesis Kre9/Knh1-like N-terminal
Transcription initiation factor TFIID subunit 1 histone acetyltransferase
Transcription factor tau subunit sfc3/Tfc3 C-terminal
Pseudouridine synthase I TruA alpha/beta
Exocyst complex component Sec3 PIP2-binding N-terminal
SAM-dependent methyltransferase TRM5/TYW2-type
Proton acceptor; for 3-dehydroquinate dehydratase activity
Proton acceptor; for 3-dehydroquinate synthase activity
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity
Shikimate dehydrogenase substrate binding N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
SAM-dependent methyltransferase Erg6/SMT-type
Ribose-phosphate pyrophosphokinase N-terminal
Cytoplasmic tRNA 2-thiolation protein 1 C-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
10TM putative phosphate transporter extracellular tail
CSC1/OSCA1-like N-terminal transmembrane
Nuclear abundant poly(A) RNA-binding protein Nab2 N-terminal
Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1
Vesicle tethering protein Uso1/P115-like head
Ubiquitin-protein ligase E3A N-terminal zinc-binding
Lethal giant larvae (Lgl)-like C-terminal
Small ribosomal subunit protein uS4 N-terminal
DNA mismatch repair protein HSM3 C-terminal
DNA mismatch repair protein HSM3 N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Nitrogen regulatory protein areA GATA-like
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
RNA polymerase subunit H/Rpb5 C-terminal
3-beta hydroxysteroid dehydrogenase/isomerase
Co-chaperone HscB C-terminal oligomerisation
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Telomeric single stranded DNA binding POT1/Cdc13
Coatomer gamma subunit appendage Ig-like subdomain
Alkali metal cation/H+ antiporter Nha1 C-terminal
RecQ mediated genome instability protein 1 N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase 1 alpha chain
Phosphatidylserine decarboxylase 1 beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Histone acetyl transferase HAT1 N-terminal
Exocyst complex component Sec8 N-terminal
Mitochondrial escape protein 2 C-terminal
SAPK-interacting protein 1 Pleckstrin-homology
Minichromosome loss protein Mcl1 middle region
Origin recognition complex subunit 3 N-terminal
Origin recognition complex subunit 3 winged helix C-terminal
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Post-GPI attachment to proteins factor 3
Pre-rRNA-processing protein Ipi1 N-terminal
C4-type zinc-finger of DNA polymerase delta
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
U3 small nucleolar RNA-associated protein 15 C-terminal
Mitochondrial splicing suppressor 51 zinc-finger
Mitochondrial splicing suppressor 51-like C-terminal
Meiotically up-regulated protein Msb1/Mug8
Retrograde transport protein Dsl1 C-terminal
Retrograde transport protein Dsl1 N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal
Coatomer beta subunit appendage platform
Sodium/calcium exchanger membrane region
Transcription factor IIIC putative zinc-finger
Spindle pole body component Bbp1 C-terminal
Ubiquitin-activating enzyme E1 C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
Pre-mRNA cleavage complex subunit Clp1 C-terminal
RNA 3'-terminal phosphate cyclase insert
Chromosome segregation in meiosis protein 3
Histone chaperone RTT106/FACT complex subunit SPT16-like middle
Nucleolar 27S pre-rRNA processing Urb2/Npa2 C-terminal
Mediator complex subunit Med13 C-terminal
Mediator complex subunit Med13 N-terminal
U3 small nucleolar RNA-associated protein 20 C-terminal
U3 small nucleolar RNA-associated protein 20 N-terminal
Siroheme biosynthesis protein Met8 C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Peptide methionine sulphoxide reductase MsrA
Phosphatidylserine decarboxylase 2 alpha chain
Phosphatidylserine decarboxylase 2 beta chain
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
Sporulation-specific protein 71 N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Transcriptional coactivator p15 (PC4) C-terminal
Transcription factor CBF/NF-Y/archaeal histone
Cleavage stimulation factor subunit 2 hinge
Transcription termination and cleavage factor C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Large ribosomal subunit protein uL30 N-terminal eukaryotes
Cleavage/polyadenylation specificity factor A subunit C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Small nuclear ribonucleoprotein Prp3 C-terminal
Non-structural maintenance of chromosomes element 1 RING C4HC3-type
non-specific serine/threonine protein kinase
Rapamycin-insensitive companion of mTOR N-terminal
Rapamycin-insensitive companion of mTOR middle
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Transcription factor TFIID subunit 8 C-terminal
Interaction with phosphoserine on interacting protein
Thymidylate synthase/dCMP hydroxymethylase
6-phosphogluconate dehydrogenase C-terminal
Histone deacetylase complex subunit SAP30 Sin3 binding
Large ribosomal subunit protein uL6 alpha-beta
Origin recognition complex subunit 5 C-terminal
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Thiamin pyrophosphokinase thiamin-binding
Programmed cell death protein 2 C-terminal
Peroxisome membrane anchor protein Pex14p N-terminal
Glycylpeptide N-tetradecanoyltransferase C-terminal
Glycylpeptide N-tetradecanoyltransferase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Small ribosomal subunit protein uS17 N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Signal recognition particle SRP72 subunit RNA-binding
Large ribosomal subunit protein uL23 N-terminal
1,3-beta-glucan synthase component FKS1-like
DNA replication checkpoint mediator MRC1
Transcription factor IIIC subunit Tfc1/Sfc1 triple barrel
Pre-rRNA-processing protein RIX1 N-terminal
Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain
Telomerase activating protein Est1-like N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Nuclear condensin complex subunit 3 C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
DSC E3 ubiquitin ligase complex subunit 3 C-terminal
DSC E3 ubiquitin ligase complex subunit 3 ubiquitin-like
Cleavage/polyadenylation specificity factor A subunit N-terminal
Phosphatidylinositol-specific phospholipase C X
S-adenosyl-L-homocysteine hydrolase NAD binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Hap4 transcription factor heteromerisation
GPI ethanolamine phosphate transferase 1 C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Rad21/Rec8-like protein C-terminal eukaryotic
RNA polymerase II-associated protein 1 C-terminal
RNA polymerase II-associated protein 1 N-terminal
Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central
Schiff-base intermediate with D-ribose 5-phosphate
Spindle body associated protein C-terminal
Phosphatidate phosphatase APP1 catalytic
Yeast SAGA-associated factor 11 N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Ubiquitin-like modifier-activating enzyme Atg7 N-terminal
Alpha-glycerophosphate oxidase C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
CTD kinase subunit gamma Ctk3 C-terminal
Telomere-associated protein Rif1 N-terminal
Damage-control phosphatase ARMT1-like metal-binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
Transcriptional regulatory protein RXT2 N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
FACT complex subunit Spt16 N-terminal lobe
Small ribosomal subunit protein uS15 N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Glutaminyl-tRNA synthetase class Ib non-specific RNA-binding
ER membrane protein complex subunit 1 C-terminal
IMS import disulfide relay-system CHCH-CHCH-like Cx9C
Apoptosis-antagonizing transcription factor C-terminal
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
DNA endonuclease activator Ctp1 C-terminal
Transcription initiation factor TFIID component TAF4 C-terminal
DNA polymerase epsilon catalytic subunit A C-terminal
Transcription factor TFIIIC triple barrel
Alanyl-transfer RNA synthetases family profile
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Origin recognition complex subunit 4 C-terminal
Fe-S cluster assembly protein Dre2 N-terminal
Glycosyl transferase family 28 C-terminal
Phosphomannose isomerase type I C-terminal
Phosphomannose isomerase type I catalytic
Phosphomannose isomerase type I helical insertion
DNA polymerase alpha catalytic subunit N-terminal
Zinc finger DNA-directed DNA polymerase family B alpha
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Manganese/iron superoxide dismutase N-terminal
Mating factor alpha precursor N-terminal
Small ribosomal subunit protein mS35 mitochondrial conserved
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Nucleolar pre-ribosomal-associated protein 1 C-terminal
Nucleolar pre-ribosomal-associated protein 1 N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Bridge-like lipid transfer protein family member 1 N-terminal
Ribosomal RNA-processing protein 14 N-terminal
Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
UDP-N-acetylglucosamine transferase subunit ALG14
DNA-directed RNA polymerase I subunit RPA2