Alpha-glycerophosphate oxidase C-terminal
Solute-binding protein family 3/N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Penicillin-binding protein transpeptidase
Type VI secretion system IcmF C-terminal
Outer membrane protein beta-barrel domain-containing protein
RND efflux pump membrane fusion protein barrel-sandwich
Translation elongation factor P/YeiP central
Large ribosomal subunit protein uL6 alpha-beta
Membrane insertase YidC/Oxa/ALB C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Acyl-CoA dehydrogenase C-terminal bacterial-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Major facilitator superfamily (MFS) profile
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Cytochrome c-type biogenesis protein CcmF C-terminal
Glycine cleavage T-protein C-terminal barrel
Saccharopine dehydrogenase-like C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Outer membrane protein assembly factor BamA
Ribosomal RNA adenine methylase transferase N-terminal
Transposase IS116/IS110/IS902 C-terminal
Pseudouridine synthase I TruA alpha/beta
Ionotropic glutamate receptor C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Transposase IS204/IS1001/IS1096/IS1165 DDE
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Inverse autotransporter beta-domain domain-containing protein
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Biopterin-dependent aromatic amino acid hydroxylase family profile
Pyrimidine nucleoside phosphorylase C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
O-(5'-phospho-DNA)-tyrosine intermediate
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Schiff-base intermediate with acetoacetate
Glucosamine/galactosamine-6-phosphate isomerase
Membrane fusion protein biotin-lipoyl like
Helix-hairpin-helix DNA-binding motif class 1
Putative regulatory protein FmdB Zinc ribbon
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Polymerase/histidinol phosphatase N-terminal
Murein L,D-transpeptidase catalytic domain family protein
Putative oxidoreductase/dehydrogenase Rossmann-like
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
UDP N-acetylglucosamine O-acyltransferase C-terminal
DNA replication/recombination mediator RecO N-terminal
Anthranilate synthase component I N-terminal
Interaction with polymerase core subunit RpoC
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Pyruvate phosphate dikinase AMP/ATP-binding
Shikimate dehydrogenase substrate binding N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Prokaryotic-type class I peptide chain release factors
DNA-directed DNA polymerase family A palm
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
DNA polymerase III subunit delta C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Heme-copper oxidase subunit III family profile
Ribose-phosphate pyrophosphokinase N-terminal
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
DNA mismatch repair proteins mutS family
Lysidine-tRNA(Ile) synthetase C-terminal
Lytic transglycosylase MltA domain-containing protein
Choloylglycine hydrolase/NAAA C-terminal
Superoxide dismutase copper/zinc binding
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Polysaccharide biosynthesis protein CapD-like
Adaptive response protein AidB N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Type II secretion system protein GspG C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Large ribosomal subunit protein uL15/eL18
Essential for prephenate dehydratase activity
NADH:ubiquinone oxidoreductase-like 20kDa subunit
3-beta hydroxysteroid dehydrogenase/isomerase
DNA polymerase III delta subunit C-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Cysteine sulfenic acid (-SOH) intermediate
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
2-oxoacid dehydrogenase acyltransferase catalytic
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Sodium/calcium exchanger membrane region
Outer-membrane lipoprotein carrier protein
Outer membrane protein assembly factor BamD
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Gly-cisPro motif, important for rejection of L-amino acids
Important for beta-aspartyl-AMP intermediate formation
Glycine zipper domain-containing protein
Chromosomal replication initiator protein DnaA
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
RNA 2-O ribose methyltransferase substrate binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Bacterial type II secretion system protein E
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Small ribosomal subunit protein uS4 N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Proline utilization A proline dehydrogenase N-terminal
Thiol:disulfide interchange protein DsbD
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Important for substrate binding and specificity
Arginine decarboxylase C-terminal helical
Phosphatidic acid phosphatase type 2/haloperoxidase
Gfo/Idh/MocA-like oxidoreductase N-terminal
Survival protein SurE-like phosphatase/nucleotidase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Phosphoribosylformylglycinamidine synthase linker
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Could be important to modulate the pK values of the two catalytic cysteine residues
Signal recognition particle SRP54 helical bundle
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
L,D-transpeptidase catalytic domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Glycosyltransferase subfamily 4-like N-terminal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
ABC-type transport auxiliary lipoprotein component
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Cell division protein FtsQ/DivIB C-terminal
Translocation and assembly module subunit TamA
Alanyl-transfer RNA synthetases family profile
Type II secretion system protein GspC N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glycosyl transferase family 3 N-terminal
NIF system FeS cluster assembly NifU N-terminal
PHA accumulation regulator DNA-binding N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
ATP synthase F1 complex delta/epsilon subunit N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Carbamoyl-phosphate synthase small subunit N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Putative conjugal transfer nickase/helicase TraI C-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Release factor glutamine methyltransferase N-terminal
Plays an important role in substrate specificity
Tryptophan synthase beta chain-like PALP
SUF system FeS cluster assembly SufBD N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Lipocalin-like domain-containing protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Type II secretion system protein GspI C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Proton acceptor; for glutaminase activity
Cytochrome b561 bacterial/Ni-hydrogenase
NADH:ubiquinone oxidoreductase 30kDa subunit
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
Gfo/Idh/MocA-like oxidoreductase C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Histidine-specific methyltransferase SAM-dependent
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Large ribosomal subunit protein uL2 C-terminal
Endolytic peptidoglycan transglycosylase RlpA
Important for interaction with partner proteins