Thiamine pyrophosphate enzyme TPP-binding
DNA mismatch repair proteins mutS family
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
C-type lysozyme inhibitor domain-containing protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Thymidylate synthase/dCMP hydroxymethylase
Outer membrane protein beta-barrel domain-containing protein
NADH:ubiquinone oxidoreductase 30kDa subunit
Outer membrane protein assembly factor BamA
Integrating conjugative element protein PilL, PFGI-1 class
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Bacterial type II secretion system protein E
Could be important to modulate the pK values of the two catalytic cysteine residues
Cytochrome b561 bacterial/Ni-hydrogenase
Outer-membrane lipoprotein carrier protein
Penicillin-binding protein transpeptidase
Gly-cisPro motif, important for rejection of L-amino acids
Putative regulatory protein FmdB Zinc ribbon
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Major facilitator superfamily (MFS) profile
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Solute-binding protein family 3/N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Inverse autotransporter beta-domain domain-containing protein
Biopterin-dependent aromatic amino acid hydroxylase family profile
Large ribosomal subunit protein uL2 C-terminal
Type II secretion system protein GspI C-terminal
Membrane fusion protein biotin-lipoyl like
RND efflux pump membrane fusion protein barrel-sandwich
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Plays an important role in substrate specificity
Flagellar motor switch protein FliN-like C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Cation-transporting P-type ATPase N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Ionotropic glutamate receptor C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Endolytic peptidoglycan transglycosylase RlpA
Proton acceptor; for glutaminase activity
Alpha-D-phosphohexomutase alpha/beta/alpha
S-adenosylmethionine-dependent methyltransferase
Glycosyltransferase subfamily 4-like N-terminal
Type IV secretion system coupling protein TraD DNA-binding
Inosine/uridine-preferring nucleoside hydrolase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Protein with a bacterial immunoglobulin-like domain
Interaction with polymerase core subunit RpoC
Thiamine pyrophosphate enzyme N-terminal TPP-binding
EfeO-type cupredoxin-like domain-containing protein
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Signal recognition particle SRP54 helical bundle
Type VI secretion system IcmF C-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Lysozyme inhibitor LprI N-terminal domain-containing protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Tetrahydrodipicolinate-N-succinyltransferase chain A
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Pyridoxamine 5'-phosphate oxidase putative
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Cytochrome c-type biogenesis protein CcmF C-terminal
Heme-copper oxidase subunit III family profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
DNA replication/recombination mediator RecO N-terminal
Prepilin type IV endopeptidase peptidase
N-acetylmuramoyl-L-alanine amidase domain-containing protein
Glycine cleavage T-protein C-terminal barrel
Polysaccharide chain length determinant N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Type II secretion system protein GspG C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Chromosomal replication initiator DnaA C-terminal
Saccharopine dehydrogenase-like C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Polymerase/histidinol phosphatase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Outer membrane protein OmpA-like transmembrane
Outer membrane protein OmpA-like transmembrane domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Schiff-base intermediate with substrate; via pyruvic acid
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Histidine-specific methyltransferase SAM-dependent
ABC-type transport auxiliary lipoprotein component
Polysaccharide biosynthesis protein CapD-like
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Anthranilate synthase component I N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Mannose-6-phosphate isomerase type II C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
DNA polymerase III subunit delta C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Bacterial transcription activator effector binding
Type I restriction modification DNA specificity
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Type II secretion system protein GspC N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Resolvase/invertase-type recombinase catalytic
Proline utilization A proline dehydrogenase N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Glycosyl transferase family 3 N-terminal
Alpha-glycerophosphate oxidase C-terminal
Proteinase inhibitor I42 chagasin domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
NIF system FeS cluster assembly NifU N-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Translation elongation factor P/YeiP central
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Phosphoadenosine phosphosulphate reductase
ATPases involved in biogenesis of archaeal flagella
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Activator of Hsp90 ATPase homologue 1-like C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Small ribosomal subunit protein uS4 N-terminal
Glycine zipper domain-containing protein
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Important for interaction with partner proteins
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Tryptophan synthase beta chain-like PALP
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Essential for prephenate dehydratase activity
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Helix-hairpin-helix DNA-binding motif class 1
Acyl-CoA dehydrogenase C-terminal bacterial-type
Large ribosomal subunit protein uL15/eL18
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Outer membrane protein assembly factor BamB
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Ribose-phosphate pyrophosphokinase N-terminal
Sodium/calcium exchanger membrane region
Lipopolysaccharide export system protein LptC
NAD(P) transhydrogenase alpha subunit C-terminal
Flagellar hook-length control protein-like C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
DNA-directed DNA polymerase family A palm
UDP N-acetylglucosamine O-acyltransferase C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Important for substrate binding and specificity
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Tellurite resistance methyltransferase TehB-like
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Schiff-base intermediate with acetoacetate
Membrane insertase YidC/Oxa/ALB C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
DNA polymerase III delta subunit C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
L,D-transpeptidase catalytic domain-containing protein
Putative ATP-dependent zinc protease domain-containing protein
Alanyl-transfer RNA synthetases family profile
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Chromosomal replication initiator protein DnaA
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
RNA polymerase sigma factor 70 region 4 type 2
N6 adenine-specific DNA methyltransferase N-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
Pyruvate phosphate dikinase AMP/ATP-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pseudouridine synthase I TruA alpha/beta
RNA 2-O ribose methyltransferase substrate binding
Ribosomal RNA adenine methylase transferase N-terminal
Prokaryotic-type class I peptide chain release factors
Transposase IS204/IS1001/IS1096/IS1165 DDE