Endoribonuclease L-PSP/chorismate mutase-like
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Glycosyltransferase subfamily 4-like N-terminal
Major facilitator superfamily (MFS) profile
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
General stress protein FMN-binding split barrel
Transposase IS116/IS110/IS902 C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Bacterial type II secretion system protein E
Polymerase/histidinol phosphatase N-terminal
Phosphomannose isomerase type I catalytic
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Lipoprotein LpqB beta-propeller domain-containing protein
Transcription regulator AsnC/Lrp ligand binding
Peptidase S9 prolyl oligopeptidase catalytic
SUF system FeS cluster assembly SufBD N-terminal
Glycosyltransferase family 28 N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Aminoacyl-transfer RNA synthetases class-II family profile
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Formamidopyrimidine-DNA glycosylase catalytic
Reversibly protonated during proton transport
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Excalibur calcium-binding domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
ABC-type glycine betaine transport system substrate-binding
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Prokaryotic-type class I peptide chain release factors
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Helix-hairpin-helix DNA-binding motif class 1
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Resolvase/invertase-type recombinase catalytic
Penicillin-binding protein transpeptidase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Ribose-phosphate pyrophosphokinase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Mannose-6-phosphate isomerase type II C-terminal
Glycosyl transferase family 28 C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Phosphotransferase system enzyme I N-terminal
Peptidase S8/S53 domain-containing protein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Glycine cleavage T-protein C-terminal barrel
Glucose-methanol-choline oxidoreductase N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Shikimate dehydrogenase substrate binding N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Gram-positive cocci surface proteins LPxTG domain-containing protein
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Phosphatidic acid phosphatase type 2/haloperoxidase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Large ribosomal subunit protein uL2 C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Alpha-glycerophosphate oxidase C-terminal
Peptidase M1 membrane alanine aminopeptidase
Fibrinogen C-terminal domain-containing protein
Bacterial bifunctional deaminase-reductase C-terminal
L-seryl-tRNA selenium transferase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Ribosomal RNA adenine methylase transferase N-terminal
6-phosphogluconate dehydrogenase C-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Phosphatidate phosphatase APP1 catalytic
Pyrimidine nucleoside phosphorylase C-terminal
NIF system FeS cluster assembly NifU N-terminal
Acyltransferase MbtK/IucB-like conserved
Glycosyl transferase family 3 N-terminal
Ionotropic glutamate receptor C-terminal
Thiopeptide-type bacteriocin biosynthesis
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Polysaccharide biosynthesis protein C-terminal
Pyruvate dehydrogenase E1 component middle
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Schiff-base intermediate with substrate; via pyruvic acid
Molybdopterin cofactor biosynthesis C (MoaC)
Chromosomal replication initiator DnaA C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Peptidase M15B domain-containing protein
Glucose-methanol-choline oxidoreductase C-terminal
Small ribosomal subunit protein uS4 N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Anthranilate synthase component I N-terminal
Plays an important role in substrate specificity
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Schiff-base intermediate with acetaldehyde
Positions MEP for the nucleophilic attack
Putative regulatory protein FmdB Zinc ribbon
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
PhoD-like phosphatase metallophosphatase
Putative Flp pilus-assembly TadG-like N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
ABC transporter substrate-binding protein PnrA-like
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Haemophore haem-binding domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Important for substrate specificity; cannot use PPi as phosphoryl donor
Pyridoxamine 5'-phosphate oxidase putative
Phosphoribosylformylglycinamidine synthase linker
Alanyl-transfer RNA synthetases family profile
RNA 2-O ribose methyltransferase substrate binding
DNA-directed DNA polymerase family A palm
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
DNA topoisomerase I catalytic core eukaryotic-type
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
DNA replication/recombination mediator RecO N-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
SGNH hydrolase-type esterase domain-containing protein
Thymidylate synthase/dCMP hydroxymethylase
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Methionyl-tRNA synthetase anticodon-binding
Release factor glutamine methyltransferase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Threonine/serine exporter-like N-terminal
DNA primase/polymerase bifunctional N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Large ribosomal subunit protein uL15/eL18
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Large ribosomal subunit protein uL6 alpha-beta
Protein O-mannosyl-transferase C-terminal four TM
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Tryptophan synthase beta chain-like PALP
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
TetR transcriptional regulator CgmR-like C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Myo-inositol-1-phosphate synthase GAPDH-like
Aminoacyl-tRNA synthetase class I anticodon-binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Polysaccharide biosynthesis protein CapD-like
Could play a key role in the communication between the regulatory and the substrate sites
Carbamoyl-phosphate synthase small subunit N-terminal
Prepilin type IV endopeptidase peptidase
Cytochrome b/b6 N-terminal region profile
Cytochrome bc1 complex cytochrome c subunit
Prepilin type IV endopeptidase peptidase domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Heat-inducible transcription repressor HrcA C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Putative oxidoreductase/dehydrogenase Rossmann-like
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Sporulation transcription regulator WhiA N-terminal
RNA binding; important for wobble base 34 recognition
Cytochrome C biogenesis protein transmembrane
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
CobB/CobQ-like glutamine amidotransferase
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Phenol hydroxylase C-terminal dimerisation
Translation elongation factor P/YeiP central