NADH:flavin oxidoreductase/NADH oxidase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Bacterial bifunctional deaminase-reductase C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
D-inositol 3-phosphate glycosyltransferase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
ABC-type glycine betaine transport system substrate-binding
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Formamidopyrimidine-DNA glycosylase catalytic
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
DNA topoisomerase I catalytic core eukaryotic-type
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Major facilitator superfamily (MFS) profile
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Peptidase M1 membrane alanine aminopeptidase
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Tryptophan synthase beta chain-like PALP
DNA-directed RNA polymerase RpoA/D/Rpb3-type
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Glycosyltransferase 2-like prokaryotic type
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Sortase (Surface protein transpeptidase)
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Bacterial type II secretion system protein E
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Protein O-mannosyl-transferase C-terminal four TM
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Peptide methionine sulphoxide reductase MsrA
Alpha galactosidase C-terminal beta sandwich
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Pyridoxamine 5'-phosphate oxidase putative
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
RNA polymerase sigma factor 70 region 4 type 2
S-adenosyl-L-homocysteine hydrolase NAD binding
Cation-transporting P-type ATPase N-terminal
Alpha-glycerophosphate oxidase C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
General stress protein FMN-binding split barrel
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Aminoacyl-transfer RNA synthetases class-II family profile
FAD-dependent oxidoreductase 2 FAD binding
Removed in mature form; by autocatalysis
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glycoside hydrolase family 42 N-terminal
Polymerase/histidinol phosphatase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Bacterial Ig-like domain-containing protein
Mycothiol-dependent maleylpyruvate isomerase metal-binding
O-(3'-phospho-DNA)-tyrosine intermediate
Resolvase/invertase-type recombinase catalytic
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Large ribosomal subunit protein uL15/eL18
Aconitase A/isopropylmalate dehydratase small subunit swivel
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Glucosamine/galactosamine-6-phosphate isomerase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Ribosomal RNA small subunit methyltransferase E methyltransferase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Prokaryotic-type class I peptide chain release factors
Bacterial transcription activator effector binding
Pyrimidine nucleoside phosphorylase C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Heme-copper oxidase subunit III family profile
BMP family ABC transporter substrate-binding protein
DNA-directed DNA polymerase family A palm
Gram-positive cocci surface proteins LPxTG
Gram-positive cocci surface proteins LPxTG domain-containing protein
Myo-inositol-1-phosphate synthase GAPDH-like
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Right handed beta helix domain-containing protein
Putative oxidoreductase/dehydrogenase Rossmann-like
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
NIF system FeS cluster assembly NifU N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Solute-binding protein family 3/N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Cyclophilin-like domain-containing protein
Beta-hexosaminidase bacterial type N-terminal
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase
Chromosomal replication initiator DnaA C-terminal
Cobalamin-independent methionine synthase MetE N-terminal
Excalibur calcium-binding domain-containing protein
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Putative adhesin domain-containing protein
ATP synthase F1 complex delta/epsilon subunit N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Putative glycogen debranching enzyme N-terminal
Ribosome maturation factor RimP N-terminal
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
3-beta hydroxysteroid dehydrogenase/isomerase
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Penicillin-binding protein transpeptidase
Peptidase S9 prolyl oligopeptidase catalytic
Methionyl-tRNA synthetase anticodon-binding
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Threonine/serine exporter-like N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
RNA 2-O ribose methyltransferase substrate binding
Schiff-base intermediate with acetaldehyde
Essential for prephenate dehydratase activity
Electron transfer via tryptophanyl radical
Activator of Hsp90 ATPase homologue 1-like C-terminal
Alanyl-transfer RNA synthetases family profile
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Heat-inducible transcription repressor HrcA C-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
YbaK/aminoacyl-tRNA synthetase-associated
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Phosphotransferase system enzyme I N-terminal
Positions MEP for the nucleophilic attack
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Shikimate dehydrogenase substrate binding N-terminal
6-phosphogluconate dehydrogenase C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Large ribosomal subunit protein uL6 alpha-beta
Glycosyl hydrolase family 30 beta sandwich
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Ribose-phosphate pyrophosphokinase N-terminal
Anthranilate synthase component I N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Large ribosomal subunit protein uL2 C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Flagellar motor switch protein FliN-like C-terminal
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Periplasmic copper-binding protein NosD beta helix
Beta-xylosidase C-terminal Concanavalin A-like
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Carbohydrate-binding domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Mannose-6-phosphate isomerase type II C-terminal
Cell division protein FtsQ/DivIB C-terminal
PknH-like extracellular domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
Transcription regulator AsnC/Lrp ligand binding
Glycoside-hydrolase family GH114 TIM-barrel
Glycoside-hydrolase family GH114 TIM-barrel domain-containing protein
Phosphomannose isomerase type I catalytic
Electron transfer flavoprotein alpha/beta-subunit N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Proton acceptor; for glutaminase activity
Important for substrate specificity; cannot use PPi as phosphoryl donor
Phosphoribosylformylglycinamidine synthase linker
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Glycine cleavage T-protein C-terminal barrel
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
Prepilin type IV endopeptidase peptidase
Interaction with polymerase core subunit RpoC
Flagellar assembly protein FliH/Type III secretion system HrpE
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
ABC transporter substrate-binding protein PnrA-like
Translation elongation factor P/YeiP central
Glyoxalase/fosfomycin resistance/dioxygenase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Pseudouridine synthase I TruA alpha/beta
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Schiff-base intermediate with substrate; via pyruvic acid
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Could play a key role in the communication between the regulatory and the substrate sites
Endoribonuclease L-PSP/chorismate mutase-like
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Cell envelope-related transcriptional attenuator
Sporulation transcription regulator WhiA N-terminal
Glycoside hydrolase family 31 N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Septum formation-related domain-containing protein