1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glyoxalase/fosfomycin resistance/dioxygenase
Polymerase/histidinol phosphatase N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Alpha galactosidase C-terminal beta sandwich
Cell envelope-related transcriptional attenuator
Glycosyltransferase subfamily 4-like N-terminal
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Cellulose-binding Sde182 nucleoside hydrolase-like
Cytochrome C biogenesis protein transmembrane
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
RNA polymerase sigma factor 70 region 4 type 2
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Major facilitator superfamily (MFS) profile
Pyrimidine nucleoside phosphorylase C-terminal
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
Aconitase A/isopropylmalate dehydratase small subunit swivel
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Pseudouridine synthase I TruA alpha/beta
Bacterial type II secretion system protein E
Methionyl-tRNA synthetase anticodon-binding
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Peptidase S9 prolyl oligopeptidase catalytic
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glucosamine/galactosamine-6-phosphate isomerase
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
ATP-dependent DNA helicase RecG C-terminal
Large ribosomal subunit protein uL2 C-terminal
Heme-copper oxidase subunit III family profile
Alpha-N-acetylglucosaminidase C-terminal
Alpha-N-acetylglucosaminidase tim-barrel
ABC transporter substrate-binding protein PnrA-like
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
RNA 2-O ribose methyltransferase substrate binding
Pyruvate dehydrogenase E1 component middle
Transposase IS116/IS110/IS902 C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Transposase IS204/IS1001/IS1096/IS1165 DDE
Activator of Hsp90 ATPase homologue 1-like C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Endoribonuclease L-PSP/chorismate mutase-like
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Right handed beta helix domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
DNA replication/recombination mediator RecO N-terminal
Glycine cleavage T-protein C-terminal barrel
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Cytochrome oxidase subunit II copper A binding
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Schiff-base intermediate with acetaldehyde
ABC-type glycine betaine transport system substrate-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Tryptophan synthase beta chain-like PALP
Glycoside hydrolase family 42 N-terminal
Nitrite/Sulfite reductase ferredoxin-like
O-(3'-phospho-DNA)-tyrosine intermediate
Threonine/serine exporter-like N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Ribose-phosphate pyrophosphokinase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Schiff-base intermediate with D-ribose 5-phosphate
Cytochrome b/b6 N-terminal region profile
Solute-binding protein family 3/N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Sporulation transcription regulator WhiA N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Prokaryotic-type class I peptide chain release factors
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Membrane insertase YidC/Oxa/ALB C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Resolvase/invertase-type recombinase catalytic
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Translation elongation factor P/YeiP central
Alpha-glycerophosphate oxidase C-terminal
Glycerophosphoryl diester phosphodiesterase membrane
Reversibly protonated during proton transport
Penicillin-binding protein transpeptidase
Chromosomal replication initiator DnaA C-terminal
Phosphomannose isomerase type I catalytic
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glycosyl transferase family 28 C-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Glycosyltransferase family 28 N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
6-phosphogluconate dehydrogenase C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; for glutaminase activity
Phosphotransferase system enzyme I N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Transcription regulator AsnC/Lrp ligand binding
Glycosyl transferase family 3 N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Release factor glutamine methyltransferase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Inosine/uridine-preferring nucleoside hydrolase
Could play a key role in the communication between the regulatory and the substrate sites
Large ribosomal subunit protein uL6 alpha-beta
Essential for prephenate dehydratase activity
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Could be important to modulate the pK values of the two catalytic cysteine residues
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Restriction system protein Mrr-like N-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Acyl-CoA dehydrogenase/oxidase C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Alanyl-transfer RNA synthetases family profile
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
YbaK/aminoacyl-tRNA synthetase-associated
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Glucose-methanol-choline oxidoreductase N-terminal
Beta-xylosidase C-terminal Concanavalin A-like
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Putative regulatory protein FmdB Zinc ribbon
Schiff-base intermediate with substrate; via pyruvic acid
Large ribosomal subunit protein uL15/eL18
Type III restriction enzyme C-terminal endonuclease
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Thymidylate synthase/dCMP hydroxymethylase
Cysteine sulfenic acid (-SOH) intermediate
Gly-cisPro motif, important for rejection of L-amino acids
Exonuclease VII large subunit C-terminal
General stress protein FMN-binding split barrel
Meso-diaminopimelate D-dehydrogenase C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Shikimate dehydrogenase substrate binding N-terminal
Gram-positive cocci surface proteins LPxTG domain-containing protein
Heat-inducible transcription repressor HrcA C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Sodium/calcium exchanger membrane region
Important for substrate specificity; cannot use PPi as phosphoryl donor
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Transcriptional regulator LacI/GalR-like sensor
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Polysaccharide chain length determinant N-terminal
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase
Ribosomal RNA adenine methylase transferase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyrroline-5-carboxylate reductase dimerisation
Peptidase M1 membrane alanine aminopeptidase
Glycoside hydrolase GH146 substrate-binding
Resuscitation-promoting factor core lysozyme-like
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Glycoside hydrolase family 31 N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Phosphoribosylformylglycinamidine synthase linker
Small ribosomal subunit protein uS4 N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Mitochondrial apoptosis-inducing factor C-terminal
DNA-directed DNA polymerase family A palm
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Atrophied bacterial Ig domain-containing protein
Trigger factor ribosome-binding bacterial
Carbamoyl-phosphate synthase small subunit N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
L-seryl-tRNA selenium transferase N-terminal
AAA ATPase forming ring-shaped complexes
NIF system FeS cluster assembly NifU N-terminal
Putative Flp pilus-assembly TadG-like N-terminal
Gram-positive cocci surface proteins LPxTG