Ribose-phosphate pyrophosphokinase N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Release factor glutamine methyltransferase N-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
Glycoside hydrolase family 57 N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
RND efflux pump membrane fusion protein barrel-sandwich
Penicillin-binding protein transpeptidase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Signal recognition particle SRP54 helical bundle
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Bacterial type II secretion system protein E
Thiol:disulfide interchange protein DsbD
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Prokaryotic-type class I peptide chain release factors
Alpha-D-phosphohexomutase alpha/beta/alpha
HicB-like antitoxin of toxin-antitoxin system
TonB-dependent receptor-like beta-barrel
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Phosphoadenosine phosphosulphate reductase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Type I restriction modification DNA specificity
Anthranilate synthase component I N-terminal
ATP-dependent DNA helicase RecG C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Small-conductance mechanosensitive channel
High potential iron-sulfur proteins family profile
CRISPR-associated protein Cas6 C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Nucleophile; cysteine thiosulfonate intermediate
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
NADH:ubiquinone oxidoreductase-like 20kDa subunit
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Mannose-6-phosphate isomerase type II C-terminal
DNA-directed DNA polymerase family A palm
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glycine-zipper-containing OmpA-like membrane
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Lipocalin-like domain-containing protein
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Large ribosomal subunit protein uL15/eL18
Tetrahydrodipicolinate-N-succinyltransferase chain A
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Type 4 fimbrial biogenesis protein PilX N-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Sodium/calcium exchanger membrane region
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Interaction with polymerase core subunit RpoC
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Alpha-glycerophosphate oxidase C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Pyruvate phosphate dikinase AMP/ATP-binding
Glycosyl transferase family 3 N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Tryptophan synthase beta chain-like PALP
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein uL2 C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Ribosomal RNA adenine methylase transferase N-terminal
Putative regulatory protein FmdB Zinc ribbon
Tetratricopeptide repeat-containing protein
Polymerase/histidinol phosphatase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Acetylserotonin O-methyltransferase dimerisation
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
peptide-methionine (R)-S-oxide reductase
Acyl-CoA dehydrogenase C-terminal bacterial-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Polysaccharide biosynthesis protein CapD-like
Outer membrane protein beta-barrel domain-containing protein
Transposase IS116/IS110/IS902 C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Tc toxin complex TcA C-terminal TcB-binding
Proton acceptor; for glutaminase activity
Thymidylate synthase/dCMP hydroxymethylase
Lipoprotein-attachment site-containing protein
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Secreted protein with PEP-CTERM sorting signal
Mechanosensitive ion channel inner membrane
Flagellar hook-length control protein-like C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Phosphotransferase system enzyme I N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Glycoside hydrolase family 42 N-terminal
NIF system FeS cluster assembly NifU N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Aminoacyl-tRNA synthetase class I anticodon-binding
Outer-membrane lipoprotein carrier protein
Disulphide bond isomerase DsbC/G N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Carbamoyl-phosphate synthase small subunit N-terminal
DNA polymerase III subunit delta C-terminal
Terminase large subunit gp17-like C-terminal
Peptide methionine sulphoxide reductase MsrA
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Major facilitator superfamily associated
Helix-hairpin-helix DNA-binding motif class 1
O-(5'-phospho-DNA)-tyrosine intermediate
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Large ribosomal subunit protein uL6 alpha-beta
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Type II secretion system protein GspG C-terminal
Transcription factor NikR nickel binding C-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Major facilitator superfamily (MFS) profile
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Cation-transporting P-type ATPase N-terminal
Electron transfer via tryptophanyl radical
Putative beta-lactamase-inhibitor-like PepSY-like
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Lysozyme inhibitor LprI N-terminal domain-containing protein
Flagellar motor switch protein FliN-like C-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Cytochrome c-type biogenesis protein CcmF C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Invasion associated locus B (IalB) protein
DNA mismatch repair proteins mutS family
Translation elongation factor P/YeiP central
S-adenosyl-L-homocysteine hydrolase NAD binding
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Shikimate dehydrogenase substrate binding N-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Ribulose bisphosphate carboxylase small subunit
Exonuclease VII large subunit C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Plays an important role in substrate specificity
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Peptidase propeptide and YPEB domain-containing protein
Could play a key role in the communication between the regulatory and the substrate sites
Could be important to modulate the pK values of the two catalytic cysteine residues
Nitrite/Sulfite reductase ferredoxin-like
Reversibly protonated during proton transport
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Essential for prephenate dehydratase activity
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Survival protein SurE-like phosphatase/nucleotidase
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Positions MEP for the nucleophilic attack
Prepilin type IV endopeptidase peptidase
Glycosyltransferase subfamily 4-like N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
DNA-3-methyladenine glycosylase AlkA N-terminal
Heme-copper oxidase subunit III family profile
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
PEP-CTERM protein-sorting domain-containing protein
Histidine-specific methyltransferase SAM-dependent
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Acyltransferase MbtK/IucB-like conserved
Alanyl-transfer RNA synthetases family profile
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
RNA binding; important for wobble base 34 recognition
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
N-end rule aminoacyl transferase C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Small ribosomal subunit protein uS4 N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Pseudouridine synthase I TruA alpha/beta
Flagellar assembly protein FliH/Type III secretion system HrpE
Important for interaction with partner proteins