Cysteine sulfenic acid (-SOH) intermediate
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Gp5/Type VI secretion system Vgr protein OB-fold
Pyrroline-5-carboxylate reductase catalytic N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
RNA polymerase sigma factor 70 region 4 type 2
Beta-lactamase hydrolase-like protein phosphatase-like
Lipoprotein SmpA/OmlA domain-containing protein
Major facilitator superfamily (MFS) profile
Type VI secretion system IcmF C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Tryptophan synthase beta chain-like PALP
Interaction with polymerase core subunit RpoC
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Glycosyl transferase family 3 N-terminal
YaiO family beta-barrel domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
Pyridoxamine 5'-phosphate oxidase putative
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
ABC-type glycine betaine transport system substrate-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Type III restriction enzyme C-terminal endonuclease
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Phosphoadenosine phosphosulphate reductase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Cation-transporting P-type ATPase N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Alanyl-transfer RNA synthetases family profile
Disulphide bond isomerase DsbC/G N-terminal
Important for interaction with partner proteins
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Penicillin-binding protein transpeptidase
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Guanine nucleotide exchange factor SopE GEF
Yop protein translocation protein D periplasmic
Ribonucleotide reductase large subunit C-terminal
Bulb-type lectin domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Pyrroline-5-carboxylate reductase dimerisation
Gamma-butyrobetaine hydroxylase-like N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Moves into active site upon enzyme activation, plays a role in electron transfer
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Poly-beta-hydroxybutyrate polymerase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
UDP-glucose/GDP-mannose dehydrogenase C-terminal
TonB-dependent receptor-like beta-barrel
Flagellar hook-length control protein-like C-terminal
Flagellar motor switch protein FliN-like C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Sodium/calcium exchanger membrane region
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Chitobiase/beta-hexosaminidases N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Mannose-6-phosphate isomerase type II C-terminal
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
NAD(P) transhydrogenase alpha subunit C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Anthranilate synthase component I N-terminal
Bacterial type II secretion system protein E
Antitoxin Xre/MbcA/ParS-like toxin-binding
Acetylserotonin O-methyltransferase dimerisation
Ribosomal RNA adenine methylase transferase N-terminal
Polymerase/histidinol phosphatase N-terminal
Large ribosomal subunit protein uL15/eL18
NIF system FeS cluster assembly NifU N-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Malonate/sodium symporter MadM subunit N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Outer membrane protein assembly factor BamA
Flagellar assembly protein FliH/Type III secretion system HrpE
Membrane fusion protein biotin-lipoyl like
N-end rule aminoacyl transferase C-terminal
Signal recognition particle SRP54 helical bundle
Transposase IS204/IS1001/IS1096/IS1165 DDE
Peptidase M1 membrane alanine aminopeptidase
Terminase large subunit-like endonuclease
Reversibly protonated during proton transport
NADH:ubiquinone oxidoreductase 30kDa subunit
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Inward rectifier potassium channel C-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Aminoacyl-transfer RNA synthetases class-II family profile
Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
Pilus formation protein N-terminal domain-containing protein
RND efflux pump membrane fusion protein barrel-sandwich
Small ribosomal subunit protein uS4 N-terminal
Peptidase C19 ubiquitin carboxyl-terminal hydrolase
Pyruvate dehydrogenase E1 component middle
Outer membrane lipoprotein-sorting protein
Translation elongation factor P/YeiP central
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Peptidase S9 prolyl oligopeptidase catalytic
Molybdenum cofactor biosynthesis protein F N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Chromosomal replication initiator DnaA C-terminal
RNA 2-O ribose methyltransferase substrate binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
N6 adenine-specific DNA methyltransferase N-terminal
Prepilin type IV endopeptidase peptidase
Activator of Hsp90 ATPase homologue 1-like C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Virulence factor membrane-bound polymerase C-terminal
Glycine zipper 2TM domain-containing protein
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Glucose-methanol-choline oxidoreductase N-terminal
Pseudouridine synthase I TruA alpha/beta
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Putative type VI secretion system Rhs element associated Vgr
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Polysaccharide chain length determinant N-terminal
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Gamma-glutamylcyclotransferase AIG2-like
PHA accumulation regulator DNA-binding N-terminal
Proline utilization A proline dehydrogenase N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Putative Flp pilus-assembly TadG-like N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
DnaJ homologue subfamily C member 28 conserved
Thymidylate synthase/dCMP hydroxymethylase
Cytochrome b561 bacterial/Ni-hydrogenase
SUF system FeS cluster assembly SufBD N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Important for beta-aspartyl-AMP intermediate formation
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Lysozyme inhibitor LprI N-terminal domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
EfeO-type cupredoxin-like domain-containing protein
UDP N-acetylglucosamine O-acyltransferase C-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Alginate export domain-containing protein
Heme-copper oxidase subunit III family profile
Mandelate racemase/muconate lactonizing enzyme C-terminal
D-galactarate/Altronate dehydratase C-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Release factor glutamine methyltransferase N-terminal
Putative glycogen debranching enzyme N-terminal
Electron transfer flavoprotein alpha subunit C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Glucosamine/galactosamine-6-phosphate isomerase
Large ribosomal subunit protein uL2 C-terminal
Type II secretion system protein GspG C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Electron transfer via tryptophanyl radical
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Resolvase/invertase-type recombinase catalytic
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Helix-hairpin-helix DNA-binding motif class 1
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Transcription factor LuxR-like autoinducer-binding
Ysc84 actin-binding domain-containing protein
Exonuclease VII large subunit C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Integral membrane protein YccS N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
DNA-3-methyladenine glycosylase AlkA N-terminal
Glycine cleavage T-protein C-terminal barrel
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pyrimidine nucleoside phosphorylase C-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Surface antigen domain-containing protein
Water stress and hypersensitive response
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
DNA mismatch repair proteins mutS family
O-(3'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL6 alpha-beta
Quercetin 2,3-dioxygenase C-terminal cupin
Outer membrane protein beta-barrel domain-containing protein
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Glycosyltransferase 2-like prokaryotic type
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
ATP synthase F1 complex delta/epsilon subunit N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Glycoside hydrolase family 13 N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Type VI secretion lipoprotein, VC_A0113 family
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Insecticide toxin TcdB middle/N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Adaptive response protein AidB N-terminal
Transposase IS116/IS110/IS902 C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Sodium symporter small subunit predicted
Seems to be a necessary countercharge to the potassium cations
Prokaryotic-type class I peptide chain release factors
Sulfatase-modifying factor enzyme domain-containing protein
Proton acceptor; for glutaminase activity
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
L-seryl-tRNA selenium transferase N-terminal
Hypersensitivity response secretion-like HrpJ
Type III secretion system effector delivery regulator TyeA
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Molybdopterin cofactor biosynthesis C (MoaC)
Involved in tetramerization or stability of the tetramer
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 central catalytic
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
HicB-like antitoxin of toxin-antitoxin system
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Phospholipase D-like domain-containing protein
Shikimate dehydrogenase substrate binding N-terminal
Polysaccharide biosynthesis protein CapD-like
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Outer membrane protein assembly factor BamB
Arsenite oxidase subunit AioA/Iodate reductase subunit IdrA 3Fe-4S cluster
Superoxide dismutase copper/zinc binding
O-(5'-phospho-DNA)-tyrosine intermediate
Flagellar hook-basal body complex protein FliE
Outer membrane protein assembly factor BamD
Tetrahydrodipicolinate-N-succinyltransferase chain A
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
O-(phosphoribosyl dephospho-coenzyme A)serine
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Nucleophile; cysteine thiosulfonate intermediate
D-(-)-3-hydroxybutyrate oligomer hydrolase
C-type lysozyme inhibitor domain-containing protein
Alpha-glycerophosphate oxidase C-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Positions MEP for the nucleophilic attack
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
RNA binding; important for wobble base 34 recognition
Saccharopine dehydrogenase-like C-terminal
TonB-dependent hemoglobin/transferrin/lactoferrin family receptor
Plays an important role in substrate specificity
Pyruvate phosphate dikinase AMP/ATP-binding
Plays an important role in discriminating NADH against NADPH
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Putative regulatory protein FmdB Zinc ribbon
Chromosomal replication initiator protein DnaA
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-91)
Lysidine-tRNA(Ile) synthetase C-terminal
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
5-glutamyl coenzyme A thioester intermediate
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Type 2A encapsulin shell protein SrpI-like
6-phosphogluconate dehydrogenase C-terminal
Spore coat protein U domain-containing protein
DNA polymerase III subunit delta C-terminal
DNA-directed DNA polymerase family A palm
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Rap1a immunity protein domain-containing protein
Required for dimer formation and molybdate binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Aspartate/homoserine dehydrogenase NAD-binding
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Guanylate kinase/L-type calcium channel beta subunit
Secreted effector protein SptP N-terminal
Bacterial collagen-like protein middle domain-containing protein
Peptide methionine sulphoxide reductase MsrA
Biopterin-dependent aromatic amino acid hydroxylase family profile
Vanillate O-demethylase oxygenase-like C-terminal catalytic
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Schiff-base intermediate with acetoacetate
Alpha-D-phosphohexomutase alpha/beta/alpha
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Outer-membrane lipoprotein carrier protein
Phosphocysteine intermediate; for EIIB activity
Microcin J25-processing protein McjB C-terminal
Tc toxin complex TcA C-terminal TcB-binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
High potential iron-sulfur proteins family profile
Endoribonuclease L-PSP/chorismate mutase-like
Toxin co-regulated pilus biosynthesis protein Q C-terminal
Essential for prephenate dehydratase activity
Glycoside hydrolase family 42 N-terminal domain-containing protein
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Bacteriophage tail tape measure C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Could be important to modulate the pK values of the two catalytic cysteine residues
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Survival protein SurE-like phosphatase/nucleotidase
Glucose-methanol-choline oxidoreductase C-terminal